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Malic acid: fermentative production and applications

  • Mukesh Yadav ORCID logo EMAIL logo , Nirmala Sehrawat , Sunil Kumar , Anil Kumar Sharma , Manoj Singh and Amit Kumar
Published/Copyright: September 19, 2022
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Abstract

Microbial metabolites have gained lot of industrial interest. These are currently employed in various industries including pharmaceuticals, chemical, textiles, food etc. Organic acids are among the important microbial products. Production of microbial organic acids present numerous advantages like agro-industrial waste may be utilized as substrate, low production cost, natural in origin and production is environment friendly. Malic acid is an organic acid (C4 dicarboxylic acid) that can be produced by microbes. It is also useful in industrial sectors as food, chemicals, and pharmaceuticals etc. Production/extraction of malic acid has been reported from fruits, egg shells, microbes, via chemical synthesis, bio-transformation and from renewable sources. Microbial production of malic acid seems very promising due to various advantages and the approach is environment-friendly. In recent years, researchers have focused on fermentative microbial production of malic acid and possibility of using agro-industrial waste as raw substrates. In current article, malic acid production along with applications has been discussed with recent advances in the area.


Corresponding author: Mukesh Yadav, Department of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, India, E-mail:

Acknowledgment

Authors (MY, NS, AKS, MS) acknowledge the help and support by Head, Department of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, India.

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Conflict of interest statement: The authors declare no conflicts of interest regarding this article.

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Received: 2022-07-27
Accepted: 2022-08-21
Published Online: 2022-09-19

© 2022 Walter de Gruyter GmbH, Berlin/Boston

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