Fabrication and properties of poly(L-lactide)/hydroxyapatite/chitosan fiber ternary composite scaffolds for bone tissue engineering
-
Jianhao Zhao
,
Chunhong Luo
Abstract
A ternary composite scaffold of poly(L-lactide)/hydroxyapatite/chitosan fibers was fabricated for bone tissue engineering. Scanning electron microscopy analysis showed that hydroxyapatite particles and chitosan fibers in microscale uniformly distributing in poly(L-lactide) matrix not only increased the mechanical property but also prevented the crack and platelet formation on the pore surface of poly(L-lactide) matrix at cooling. The X-ray diffraction peak intensity of poly(L-lactide) component decrease may be due to the presence of hydroxyapatite particles and chitosan fibers as the crystal nuclei that led to the crystallinity decrease of poly(L-lactide). The in vitro degradation test showed that the degradation of poly(L-lactide) was resisted by enhancing the chitosan fiber content. The bone mesenchymal stem cell culture indicated that the composite scaffolds promoted the attachment and proliferation of cells, which would likely attach to and stretch along the chitosan fibers. Therefore, this ternary composite scaffold will be a promising matrix material for bone tissue engineering.
©2012 by Walter de Gruyter Berlin Boston
Articles in the same Issue
- Masthead
- Masthead
- Masthead
- Original Articles
- Evaluation of factors and kinetics study of polyacrylamide redox polymerization using statistical design modeling
- Gel filtration chromatography analysis and modeling the process of pullulan depolymerization
- Polystyrene–organoclay nanocomposites produced by in situ activators regenerated by electron transfer for atom transfer radical polymerization
- Viscoelasticity in thermoforming
- Melt extrudate swell behavior of polypropylene composites filled with hollow glass beads
- Viscosity and domain morphology in binary immiscible blends of poly(trimethylene terephthalate) and polyamide6,10
- Effect of poly (methyl methacrylate)-grafted-talc content on mechanical properties and thermal degradation of poly (vinyl chloride) composites
- Fabrication and properties of poly(L-lactide)/hydroxyapatite/chitosan fiber ternary composite scaffolds for bone tissue engineering
- Green composites based on recycled polyamide-6/recycled polypropylene kenaf composites: mechanical, thermal and morphological properties
- Effect of gamma radiation and bulk monomer on jute fabrics polyethylene/polyvinyl chloride composites
- Investigation of fracture toughness parameters of epoxy nanocomposites for different crack angles
- Influence of X-ray opaque BaSO4 nanoparticles on the mechanical, thermal and rheological properties of polyoxymethylene nanocomposites
Articles in the same Issue
- Masthead
- Masthead
- Masthead
- Original Articles
- Evaluation of factors and kinetics study of polyacrylamide redox polymerization using statistical design modeling
- Gel filtration chromatography analysis and modeling the process of pullulan depolymerization
- Polystyrene–organoclay nanocomposites produced by in situ activators regenerated by electron transfer for atom transfer radical polymerization
- Viscoelasticity in thermoforming
- Melt extrudate swell behavior of polypropylene composites filled with hollow glass beads
- Viscosity and domain morphology in binary immiscible blends of poly(trimethylene terephthalate) and polyamide6,10
- Effect of poly (methyl methacrylate)-grafted-talc content on mechanical properties and thermal degradation of poly (vinyl chloride) composites
- Fabrication and properties of poly(L-lactide)/hydroxyapatite/chitosan fiber ternary composite scaffolds for bone tissue engineering
- Green composites based on recycled polyamide-6/recycled polypropylene kenaf composites: mechanical, thermal and morphological properties
- Effect of gamma radiation and bulk monomer on jute fabrics polyethylene/polyvinyl chloride composites
- Investigation of fracture toughness parameters of epoxy nanocomposites for different crack angles
- Influence of X-ray opaque BaSO4 nanoparticles on the mechanical, thermal and rheological properties of polyoxymethylene nanocomposites
