Maternal preeclampsia is associated with an increased risk of retinopathy of prematurity
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Hilal Özkan
,
Nilgun Koksal
Abstract
Objective: To determine the effect of maternal preeclampsia on development and severity of retinopathy of prematurity (ROP) in preterm infants.
Methods: This prospective study consisted of two groups: the study group, which is composed of preterm infants (≤32 weeks) born to a mother with preeclampsia, and the comparison group, which is composed of preterm infants (≤32 gestational age) born to normotensive mothers. We used the International Classification of Retinopathy of Prematurity Revisited for classifying ROP. The first eye examination was performed at postnatal age of 4 weeks.
Results: A total of 385 infants were included in the study. ROP was diagnosed in 109 infants (28%). The incidence of ROP in infants born to preeclamptic mothers (40.5%) was significantly higher compared with those born to normotensive mothers (22.4%) (P<0.05). The number of infants with stage 1, 2, and 3 ROP was significantly higher in infants born to preeclamptic mothers compared with the control group (P<0.05). In multiple logistic regression model, preeclampsia was found to predict ROP (odds ratio 1.78, 95% confidence interval 0.66–1.90).
Conclusion: Maternal preeclampsia was found to be associated with increased ROP development risk in premature infants. ROP was also more severe in infants born to pre-eclamptic mothers. The role of maternal preeclampsia in the occurrence and severity of ROP remains to be elucidated.
©2011 by Walter de Gruyter Berlin Boston
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- Congress calendar
- Congress Calendar
Articles in the same Issue
- Review article
- Neonatal outcomes of assisted and naturally conceived twins: systematic review and meta-analysis
- Original articles – Obstetrics
- Postpartum hemorrhage in low risk population
- Perinatal mortality in preterm births: an analysis of causes, presence of substandard care and avoiding mortality in three Dutch regions
- Clinical significance of serum sRAGE and esRAGE in women with normal pregnancy and preeclampsia
- Biopsychosocial predictors of preterm delivery
- Maternal preeclampsia is associated with an increased risk of retinopathy of prematurity
- Original articles – Fetus
- Natriuretic peptide levels in intrauterine growth-restricted fetuses with absent and reversed end-diastolic flow of the umbilical artery in relation to ductus venosus flow velocities
- Inter- and intra-observer variation of fetal volume measurements with three-dimensional ultrasound in the first trimester of pregnancy
- Outcome of severe intrapartum acidemia diagnosed with fetal scalp blood sampling
- Comparison of global and regional right and left ventricular longitudinal peak systolic strain, strain rate and velocity in healthy fetuses using a novel feature tracking technique
- Contribution of twin-to-twin transfusion syndrome to preterm birth among monochorionic biamniotic and bichorionic biamniotic twin pregnancies
- Original articles – Newborn
- Historical notes on immaturity. Part 1: Measures of viability
- Historical notes on immaturity. Part 2: Surviving against the odds
- Head circumference catch-up growth among preterm very low birth weight infants: effect on neurodevelopmental outcome
- Energy metabolism in umbilical endothelial cells from preterm and term neonates
- Decision-making at the border of viability by means of values clarification: a case study to achieve distinct communication by ordinary language approach
- Neonatal morbidity in term neonates is related to gestational age at birth and level of care
- Letters to the Editor
- Effect of steroids on angiogenic factors in pregnant women with HELLP syndrome
- Acute neonatal respiratory morbidity after prior cesarean
- Congress calendar
- Congress Calendar
