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Oxytocin versus dinoprostone vaginal insert for induction of labor after previous cesarean section: a retrospective comparative study

  • Leire Rodríguez Gómez EMAIL logo , Jorge Burgos , Patricia Cobos , Juan Carlos Melchor , Carmen Osuna , Maria del Mar Centeno , Rosa Larrieta , Luis Fernández-Llebrez and Txantón Martínez-Astorquiza
Published/Copyright: May 24, 2011
Journal of Perinatal Medicine
From the journal Volume 39 Issue 4

Abstract

Objective: To compare the efficacy and safety of two methods for induction of labor after previous cesarean section.

Methods: To compare 247 women with a previous cesarean section who were induced with a dinoprostone vaginal insert and 279 women with a previous cesarean section induced with oxytocin, between 2001 and 2008. We evaluated vaginal delivery rate, maternal morbidity and newborn morbidity and mortality.

Results: The overall rate of vaginal delivery was 65.2%. We did not find significant differences between induction with dinoprostone vaginal insert and oxytocin in the rate of cesarean section performed (35.6% vs. 34.1%, P=0.71). There were nine cases of uterine rupture (rate of 1.7%), of which four occurred with dinoprostone vaginal insert and five when using oxytocin (P=0.89). We found no significant differences in neonatal outcomes.

Conclusions: Both tested methods appear to be equally safe and effective for induction of labor in women with a previous cesarean section.


Corresponding author: Leire Rodríguez Gómez Servicio de Obstetricia y Ginecología Hospital Universitario de Cruces Plaza de Cruces SN 48903 Baracaldo Vizcaya Spain Tel.: +946006000

Received: 2010-9-27
Revised: 2010-11-13
Accepted: 2010-12-29
Published Online: 2011-05-24
Published Online: 2011-05-24
Published in Print: 2011-07-01

©2011 by Walter de Gruyter Berlin Boston

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