The effect of a scheduled regimen of acetaminophen and ibuprofen on opioid use following cesarean delivery
-
Dijana Poljak
and
Joseph Chappelle
Abstract
Objective
The primary objective was to evaluate if the administration of ibuprofen and acetaminophen at regularly scheduled intervals impacts pain scores and total opioid consumption, when compared to administration based on patient demand.
Methods
A retrospective chart review was performed comparing scheduled vs. as-needed acetaminophen and ibuprofen regimens, with 100 women included in each arm. Demographics and delivery characteristics were collected in addition to pain scores and total ibuprofen, acetaminophen and oxycodone use at 24, 48 and 72 h postoperatively.
Results
The scheduled dosing group was found to have a statistically significant decrease in pain scores at all time intervals. Acetaminophen and ibuprofen usage were also noted to be higher in this group while narcotic use was reduced by 64%.
Conclusion
Scheduled dosing of non-narcotic pain medications can substantially decrease opioid usage after cesarean delivery and improve post-operative pain.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
Conflict of interest: The authors have no conflicts of interest to disclose.
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©2020 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Frontmatter
- Review
- Variations in long-term outcome reporting among offspring followed up after lifestyle interventions in pregnancy: a systematic review
- Corner of Academy
- Modifiable risk factors for spontaneous preterm birth in nulliparous women: a prospective study
- Additional benefits of three-dimensional ultrasound for prenatal assessment of twins
- Original Articles – Obstetrics
- Microbial burden and inflammasome activation in amniotic fluid of patients with preterm prelabor rupture of membranes
- Amniotic fluid concentrations of soluble endoglin and endothelial cell-specific molecule-1 in pregnancies complicated with neural tube defects
- Maternal characteristics and pregnancy outcomes of women with chronic hypertension: a population-based study
- Behavior of fetal longitudinal myocardial fibers assessed by speckle tracking to obtain strain and strain rate values for low-risk pregnancies
- The effect of a scheduled regimen of acetaminophen and ibuprofen on opioid use following cesarean delivery
- Original Articles – Fetus
- Comparison of cord blood lactate measurement by gas analyzer and portable electrochemical devices
- Perinatal mortality: epidemiological profile, causes and avoidable factors at a reference public maternity hospital in the State of Santa Catarina, Brazil, 2011–2015
- Original Articles – Newborns
- Maternal smoking and cannabis use during pregnancy and infant outcomes
- The utility of cranial ultrasound as a screening tool for neonatal ECMO
- Effects of human milk fortifier properties on intrinsic probiotic bacteria
- Letter to the Editor
- Superb microvascular imaging with Doppler luminance using an 18-MHz probe to visualize fetal intra-abdominal blood vessels and organ microvasculature
Articles in the same Issue
- Frontmatter
- Review
- Variations in long-term outcome reporting among offspring followed up after lifestyle interventions in pregnancy: a systematic review
- Corner of Academy
- Modifiable risk factors for spontaneous preterm birth in nulliparous women: a prospective study
- Additional benefits of three-dimensional ultrasound for prenatal assessment of twins
- Original Articles – Obstetrics
- Microbial burden and inflammasome activation in amniotic fluid of patients with preterm prelabor rupture of membranes
- Amniotic fluid concentrations of soluble endoglin and endothelial cell-specific molecule-1 in pregnancies complicated with neural tube defects
- Maternal characteristics and pregnancy outcomes of women with chronic hypertension: a population-based study
- Behavior of fetal longitudinal myocardial fibers assessed by speckle tracking to obtain strain and strain rate values for low-risk pregnancies
- The effect of a scheduled regimen of acetaminophen and ibuprofen on opioid use following cesarean delivery
- Original Articles – Fetus
- Comparison of cord blood lactate measurement by gas analyzer and portable electrochemical devices
- Perinatal mortality: epidemiological profile, causes and avoidable factors at a reference public maternity hospital in the State of Santa Catarina, Brazil, 2011–2015
- Original Articles – Newborns
- Maternal smoking and cannabis use during pregnancy and infant outcomes
- The utility of cranial ultrasound as a screening tool for neonatal ECMO
- Effects of human milk fortifier properties on intrinsic probiotic bacteria
- Letter to the Editor
- Superb microvascular imaging with Doppler luminance using an 18-MHz probe to visualize fetal intra-abdominal blood vessels and organ microvasculature
