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Poor sleep quality is associated with perinatal depression. A systematic review of last decade scientific literature and meta-analysis

  • Ernesto González-Mesa ORCID logo EMAIL logo , Celia Cuenca-Marín , María Suarez-Arana , Beatriz Tripiana-Serrano , Nadia Ibrahim-Díez , Ana Gonzalez-Cazorla and Marta Blasco-Alonso
Published/Copyright: August 6, 2019
Journal of Perinatal Medicine
From the journal Journal of Perinatal Medicine Volume 47 Issue 7

Abstract

Background

Although pregnancy is frequently associated with mental states of happiness, hope and well-being, some physical and psychological changes can contribute to increased sleep disturbances and worsened sleep quality. Sleep quality has been linked to negative emotions, anxiety and depression. The main objective of this paper was to systematically review the impact of sleep during pregnancy on maternal mood, studying the association between objective and subjective measures of sleep quality and perinatal depression.

Methods

We performed a systematic review according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, which included studies published between January 2008 and April 2019, and met the following criteria: (i) studies on pregnant women assessing the effects of sleep quality variables on perinatal mood disorders, (ii) studies published in English and (iii) full paper published in a peer-reviewed scientific journal with full-text format available.

Results

A total of 36 studies published in the last decade met the inclusion criteria for qualitative review and eight of them were suitable for meta-analysis. Both confirmed the negative effects of poor sleep on perinatal mood. However, qualitative analysis showed that unrepresentative samples and low participation rates falling below 80% biased some of the studies. The standard random-effects meta-analysis showed a pooled size effect [ln odds ratio (OR) 1.49 (95% confidence interval [CI] 1.19, 1.79)] for perinatal depression in cases of poor prenatal sleep quality, although heterogeneity was moderate to high [Q 16.05, P ≤ 0.025, H2 2.45 (95% CI 1.01, 13.70)].

Conclusion

Poor sleep quality was associated with perinatal mood disturbances. The assessment of sleep quality along the pregnancy could be advisable with a view to offering preventative or therapeutic interventions when necessary.

Keywords: mood disorder; perinatal depression; sleep disturbance; sleep quality
Corresponding author: Prof. Ernesto González-Mesa, MD, PHD, Surgical Specialties, Biochemistry and Immunology Department, Malaga University School of Medicine, 32, Boulevard Louis Pasteur, 29071 Málaga, Spain; and Obstetrics and Gynecology at Malaga University Hospital, Málaga, Spain

Acknowledgments

We would like to acknowledge the support of Malaga University School of Medicine and Andalusian Public Health System library staff.

  1. Author contributions: All authors participated in the design of search strategy and in the review of the included articles. EGM wrote the Methods and Discussion and submitted the article. All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Employment or leadership: None declared.

  4. Honorarium: None declared.

  5. Competing interests: The funding organisation(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.

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Received: 2019-06-12
Accepted: 2019-07-17
Published Online: 2019-08-06
Published in Print: 2019-09-25

©2019 Walter de Gruyter GmbH, Berlin/Boston

Articles in the same Issue

  1. Frontmatter
  2. Corner of Academy
  3. Hemodynamic factors associated with fetal cardiac remodeling in late fetal growth restriction: a prospective study
  4. Original Articles – Obstetrics
  5. Poor sleep quality is associated with perinatal depression. A systematic review of last decade scientific literature and meta-analysis
  6. The predictive value of serum cancer antigen 125 (CA125) levels on pregnancy outcome in threatened miscarriages
  7. Pregnancy outcomes after thyroid cancer
  8. Maternal and perinatal outcomes in external cephalic version: prognostic factors for the success of the technique
  9. Association of dietary intake below recommendations and micronutrient deficiencies during pregnancy and low birthweight
  10. The sFlt-1/PlGF ratio values within the <38, 38–85 and >85 brackets as compared to perinatal outcomes
  11. Effect of bisphenol-A (BPA) on placental biomarkers for inflammation, neurodevelopment and oxidative stress
  12. Standard and adjusted criteria for the use of the misoprostol vaginal insert for labor induction: a comparative cohort study
  13. New reference values for biometrical measurements and sonographic estimated fetal weight in twin gestations and comparison to previous normograms
  14. Simultaneous analysis of bisphenol A fractions in maternal and fetal compartments in early second trimester of pregnancy
  15. Original Articles – Fetus
  16. Antenatal ultrasound compared to MRI evaluation of fetal myelomeningocele: a prenatal and postnatal evaluation
  17. The value of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) parameters in analysis with fetal malnutrition neonates
  18. Carboxyhemoglobin in umbilical cord blood and maternal smoking
  19. Original Article – Newborn
  20. Macronutrient analysis of preterm human milk using mid-infrared spectrophotometry
https://doi.org/10.1515/jpm-2019-0214
Keywords for this article
mood disorder; perinatal depression; sleep disturbance; sleep quality

Articles in the same Issue

  1. Frontmatter
  2. Corner of Academy
  3. Hemodynamic factors associated with fetal cardiac remodeling in late fetal growth restriction: a prospective study
  4. Original Articles – Obstetrics
  5. Poor sleep quality is associated with perinatal depression. A systematic review of last decade scientific literature and meta-analysis
  6. The predictive value of serum cancer antigen 125 (CA125) levels on pregnancy outcome in threatened miscarriages
  7. Pregnancy outcomes after thyroid cancer
  8. Maternal and perinatal outcomes in external cephalic version: prognostic factors for the success of the technique
  9. Association of dietary intake below recommendations and micronutrient deficiencies during pregnancy and low birthweight
  10. The sFlt-1/PlGF ratio values within the <38, 38–85 and >85 brackets as compared to perinatal outcomes
  11. Effect of bisphenol-A (BPA) on placental biomarkers for inflammation, neurodevelopment and oxidative stress
  12. Standard and adjusted criteria for the use of the misoprostol vaginal insert for labor induction: a comparative cohort study
  13. New reference values for biometrical measurements and sonographic estimated fetal weight in twin gestations and comparison to previous normograms
  14. Simultaneous analysis of bisphenol A fractions in maternal and fetal compartments in early second trimester of pregnancy
  15. Original Articles – Fetus
  16. Antenatal ultrasound compared to MRI evaluation of fetal myelomeningocele: a prenatal and postnatal evaluation
  17. The value of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) parameters in analysis with fetal malnutrition neonates
  18. Carboxyhemoglobin in umbilical cord blood and maternal smoking
  19. Original Article – Newborn
  20. Macronutrient analysis of preterm human milk using mid-infrared spectrophotometry
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