Perinatal outcome in gestational diabetes according to different diagnostic criteria
-
Lina Salman
,
Anat Pardo
Abstract
Objectives
To evaluate whether gestational diabetes mellitus (GDM) diagnosed by different criteria impacts perinatal outcome.
Methods
This was a retrospective study of deliveries with a diagnosis of GDM (2014–2016). Perinatal outcomes were compared between patients with: (1) GDM diagnosed according to a single abnormal value on the 100-g oral glucose tolerance test (OGTT); (2) two or more abnormal OGTT values; and (3) a 50-g glucose challenge test (GCT) value ≥200 mg/dL.
Results
A total of 1163 women met the inclusion criteria, of whom 441 (37.9%) were diagnosed according to a single abnormal OGTT value, 627 (53.9%) had two or more abnormal OGTT values and 95 (8.17%) had a GCT value ≥200 mg/dL. Diet-only treatment was significantly higher in the single abnormal value group (70.3% vs. 65.1% vs. 50.5%) and rates of medical treatment were significantly higher in the GCT ≥ 200 mg/dL group (P < 0.05). Women in the GCT ≥ 200 mg/dL group had higher rates of neonatal intensive care unit (NICU) admission (10.5% vs. 2.7% vs. 2.8%, P < 0.001) and neonatal hypoglycemia (5.3% vs. 0.5% vs. 0.8%, P < 0.001). On multivariate logistic regression, GCT ≥ 200 mg/dL was no longer associated with higher rates of NICU admission and neonatal hypoglycemia (P > 0.05).
Conclusion
No difference was noted in the perinatal outcome amongst the different methods used for diagnosing GDM.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
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Articles in the same Issue
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- Expression of genes involved in inflammation and growth – does sampling site in human full-term placenta matter?
- Impact of cell-free fetal DNA on invasive prenatal diagnostic tests in a real-world public setting
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- Letters to the Editor
- Methodological issues on the clinical importance of the 75-g glucose tolerance test (GTT) in the prediction of large for gestational age (LGA) fetuses in non-diabetic pregnancies
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Articles in the same Issue
- Frontmatter
- Editorial
- Preterm premature rupture of membranes (PPROM)
- Original Articles – Obstetrics
- The value of amniotic fluid analysis in patients with suspected clinical chorioamnionitis
- Patients with acute cervical insufficiency without intra-amniotic infection/inflammation treated with cerclage have a good prognosis
- Maternal serum endocan concentrations are elevated in patients with preterm premature rupture of membranes
- The earlier the gestational age, the greater the intensity of the intra-amniotic inflammatory response in women with preterm premature rupture of membranes and amniotic fluid infection by Ureaplasma species
- Assessment of maternal GBS colonization and early-onset neonatal disease rate for term deliveries: a decade perspective
- Clinical importance of the 75-g glucose tolerance test (GTT) in the prediction of large for gestational age (LGA) fetuses in non-diabetic pregnancies
- Expression of genes involved in inflammation and growth – does sampling site in human full-term placenta matter?
- Impact of cell-free fetal DNA on invasive prenatal diagnostic tests in a real-world public setting
- Perinatal outcome in gestational diabetes according to different diagnostic criteria
- Original Articles – Fetus
- Change in fetal behavior in response to vibroacoustic stimulation
- Diagnostic accuracy of isolated clubfoot in twin compared to singleton gestations
- Original Article – Newborn
- Usefulness of transcutaneous bilirubin assessment measured in non-photo-exposed skin to guide the length of phototherapy: an observational study
- Letters to the Editor
- Methodological issues on the clinical importance of the 75-g glucose tolerance test (GTT) in the prediction of large for gestational age (LGA) fetuses in non-diabetic pregnancies
- Reply to the Letter to the Editor: methodological issues on the clinical importance of the 75-g glucose tolerance test (GTT) in the prediction of large-for-gestational-age (LGA) fetuses in non-diabetic pregnancies
