Euprolactinemic galactorrhea secondary to domperidone treatment
-
Arzu Meltem Demir
,
Zarife Kuloglu
Abstract
Milk leakage from the breast, which is known as galactorrhea, can be caused by a number of pharmacological, physical, and tumoral factors. Galactorrhea is a well-known side effect of domperidone, and is usually associated with hyperprolactinemia. However, euprolactinemic galactorrhea secondary to domperidone is very rarely seen and has yet to be reported in children before. Here, we report an adolescent with euprolactinemic galactorrhea caused by domperidone.
References
1. Katznelson L, Klibanski A. Hyperprolactinemia: physiology and clinical approach. In: Krisht AF, Tindall GT, editors. Pituitary disorders: comprehensive management. Baltimore: Lippincott Williams & Wilkins, 1999;189–98.Search in Google Scholar
2. Maton PN. Profile and assessment of GERD pharmacotherapy. Cleve Clin J Med 2003;70(Suppl 5):51–70.10.3949/ccjm.70.Suppl_5.S51Search in Google Scholar
3. Campbell-Yeo ML, Allen AC, Joseph KS, Ledwidge JM, Caddell K, et al. Effect of domperidone on the composition of preterm human breast milk. Pediatrics 2010;125:107–14.10.1542/peds.2008-3441Search in Google Scholar
4. De S, Taylor CM. Domperidone toxicity in an infant on maintenance haemodialysis. Pediatr Nephrol 2007;22;161–2.10.1007/s00467-006-0263-7Search in Google Scholar
5. Cann PA, Read NW, Holdsworth CD. Galactorrhoea as side effect of domperidone. Br Med J (Clin Res Ed) 1983;286:1395–6.10.1136/bmj.286.6375.1395Search in Google Scholar
6. Izquierdo Prieto OM, Moreno Alía E, Rosillo González A. Galactorrhea induced by lansoprazole. Aten Primaria 2004;34:325–6.10.1016/S0212-6567(04)79506-2Search in Google Scholar
7. Pratheesh PJ, Praharaj SK, Srivastava A. Euprolactinemic gynecomastia and galactorrhea with risperidone-fluvoxamine combination. Psychopharmacol Bull 2011;44:70–3.Search in Google Scholar
8. Mahasuar R, Majhi P, Ravan JR. Euprolactinemic galactorrhea associated with use of imipramine and escitalopram in a postmenopausal woman. Gen Hosp Psychiatry 2010;32:341.10.1016/j.genhosppsych.2009.07.006Search in Google Scholar PubMed
9. Kwak WJ, Patel A, Haq F, Siddiqui F, Younis M, et al. Antipsychotic-induced euprolactinemic galactorrhea in an adolescent girl: a case report. Prim Care Companion CNS Disord 2012;14.10.4088/PCC.11l01239Search in Google Scholar PubMed PubMed Central
10. Ataya KM, Subramanian MG, Lawson DM, Gala RR. Euprolactinemic galactorrhea. Response of bioassayable prolactin to thyrotropin-releasing hormone. J Reprod Med 1996;41:156–60.Search in Google Scholar
©2015 by De Gruyter
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- Original articles
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- Sulfonylurea in the treatment of neonatal diabetes mellitus children with heterogeneous genetic backgrounds
- Monitoring gonadotropin-releasing hormone analogue (GnRHa) treatment in girls with central precocious puberty: a comparison of four methods
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