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Doping with Growth Hormone
-
Martin Bidlingmaier
,
Z. Wu
Veröffentlicht/Copyright:
11. Oktober 2016
Abstract
Triggered by the Olympic games in Sydney last year, many articles in the press suggested that recombinant human growth hormone (hGH) is one of the most popular performance enhancing drugs used by athletes. However, any hard facts on hGH abuse were provided by Australian customs officers - and not by laboratory assessment. The lack of an official test for hGH doping together with the widespread rumours on its tremendous beneficial effects seem to make this compound attractive for athletes. From a scientific point of view, there are two major questions about this issue: First, as there is no controlled study demonstrating a profound effect of hGH administration on workload capacity in healthy adults, why do athletes use hGH? Second, how could the application of a substance naturally occurring in the human body be detected? Both aspects are discussed in this article.
Keywords: human growth hormone; insulin-like growth factor - I; sports; athletes; immunoassay; monoclonal antibodies
Published Online: 2016-10-11
Published in Print: 2001-9-1
© 2016 by Walter de Gruyter Berlin/Boston
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Artikel in diesem Heft
- Titelei
- Table of Contents
- Doping with Growth Hormone
- Intrauterine Diabetic Environment Confers Risks for Type 2 Diabetes Mellitus and Obesity in the Offspring, in Addition to Genetic Susceptibility
- Variable Presentation of X-linked Adrenal Hypoplasia Congenita
- Sustained Benefits of Growth Hormone on Body Composition, Fat Utilization, Physical Strength and Agility, and Growth in Prader-Willi Syndrome are Dose-Dependent
- Insufficient Adrenarche in Patients with Combined Pituitary Hormone Deficiency Caused by a PROP A Gene Defect
- Syndrome of Congenital Adrenocortical Unresponsiveness to ACTH. Report of Six Patients
- Maternal and Fetal Serum Insulin-like Growth Factor-I (IGF-I), IGF Binding Protein-3 (IGFBP-3), Leptin Levels and Early Postnatal Growth in Infants Born Asymmetrically Small for Gestational Age
- Relationships Between Levels of Leptin and Hematological Parameters in Healthy Term Infants
- Recombinant Growth Hormone Treatment in Short Patients with Thalassemia Major: Results after 24 and 36 Months
- Assessment of the Current Status of Iodine Prophylaxis in Bosnia and Herzegovina Federation
- Profiles of Obese Children Presenting for Metabolic Evaluation
- Effect of Growth Hormone Treatment on Hypoglycemia in a Patient with both Hepatic Glycogen Synthase and Isolated Growth Hormone Deficiencies
- Gliclazide-Induced Hepatitis, Hemiplegia and Dysphasia in a Suicide Attempt
- Neonatal Goiter Caused by Expectorant Usage
- Idiopathic Hypothalamic Dysfunction with Precocious Puberty and Adipsic Hypernatremia First Presenting in Adolescence
- Neonatal Hyperthyroidism m Infants of Mothers Previously Thyroidectomized due to Graves’ Disease
- Primary Hyperparathyroidism in an Infant with Three Parathyroid Glands and Pulmonary Calcinosis
- Asymmetric Crying Facies and Congenital Hypothyroidism: Report of Two Patients
- Obituary. Professor Dr. Andrea Prader (1919–2001)
- Meetings Calendar
- Author Index
Schlagwörter für diesen Artikel
human growth hormone;
insulin-like growth factor - I;
sports;
athletes;
immunoassay;
monoclonal antibodies
Artikel in diesem Heft
- Titelei
- Table of Contents
- Doping with Growth Hormone
- Intrauterine Diabetic Environment Confers Risks for Type 2 Diabetes Mellitus and Obesity in the Offspring, in Addition to Genetic Susceptibility
- Variable Presentation of X-linked Adrenal Hypoplasia Congenita
- Sustained Benefits of Growth Hormone on Body Composition, Fat Utilization, Physical Strength and Agility, and Growth in Prader-Willi Syndrome are Dose-Dependent
- Insufficient Adrenarche in Patients with Combined Pituitary Hormone Deficiency Caused by a PROP A Gene Defect
- Syndrome of Congenital Adrenocortical Unresponsiveness to ACTH. Report of Six Patients
- Maternal and Fetal Serum Insulin-like Growth Factor-I (IGF-I), IGF Binding Protein-3 (IGFBP-3), Leptin Levels and Early Postnatal Growth in Infants Born Asymmetrically Small for Gestational Age
- Relationships Between Levels of Leptin and Hematological Parameters in Healthy Term Infants
- Recombinant Growth Hormone Treatment in Short Patients with Thalassemia Major: Results after 24 and 36 Months
- Assessment of the Current Status of Iodine Prophylaxis in Bosnia and Herzegovina Federation
- Profiles of Obese Children Presenting for Metabolic Evaluation
- Effect of Growth Hormone Treatment on Hypoglycemia in a Patient with both Hepatic Glycogen Synthase and Isolated Growth Hormone Deficiencies
- Gliclazide-Induced Hepatitis, Hemiplegia and Dysphasia in a Suicide Attempt
- Neonatal Goiter Caused by Expectorant Usage
- Idiopathic Hypothalamic Dysfunction with Precocious Puberty and Adipsic Hypernatremia First Presenting in Adolescence
- Neonatal Hyperthyroidism m Infants of Mothers Previously Thyroidectomized due to Graves’ Disease
- Primary Hyperparathyroidism in an Infant with Three Parathyroid Glands and Pulmonary Calcinosis
- Asymmetric Crying Facies and Congenital Hypothyroidism: Report of Two Patients
- Obituary. Professor Dr. Andrea Prader (1919–2001)
- Meetings Calendar
- Author Index
