Can genotype determine the sports phenotype? A paradigm shift in sports medicine
-
Amit Ghosh
and
Preetam B. Mahajan
Abstract
In last two decades, there has been an evolution in sports medicine. Several researchers have worked on different domains of sports medicine, like strength, endurance, sports injury, and psychology. Besides this, several groups have explored the changes at cellular and molecular levels during exercise, which has led to the development of the new domain in sports science known as genetic medicine. Genetic medicine deals with the genotypic basis of sports phenotype. In this article, we try to provide an up-to-date review on genetic determinants of sports performance, which will be like a journey from the nostalgic past towards the traditional present and the romantic future of sports medicine. Endurance and power performance are two important domains of athletes. They vary in individuals, even among trained athletes. Researches indicate that the genetic makeup of sportsmen play a vital role in their performance. Several genetic factors are reported to be responsible for endurance, power, susceptibility to injury, and even psychology of the individual. Besides this, proper training, nutrition, and environment are also important in shaping their potential. The aim of this discussion is to understand the influence of the environment and the genetic makeup on the performance of the athletes. There is sufficient evidence to suggest that genotype determines the sports phenotype in an athlete. Choosing the right sports activity based on genetic endowment is the key for achieving excellence in sports.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
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©2016 by De Gruyter
Articles in the same Issue
- Frontmatter
- Reviews
- Assessment of paediatric pain: a critical review
- Can genotype determine the sports phenotype? A paradigm shift in sports medicine
- Oxidative Stress
- Neuroprotective effect of Decalepis hamiltonii on cyclophosphamide-induced oxidative stress in the mouse brain
- Hydroxycitric acid ameliorates high-fructose-induced redox imbalance and activation of stress sensitive kinases in male Wistar rats
- Metabolism
- Glucose absorption in the intestine of albino rats
- Inflammation
- Antinociceptive and anti-inflammatory potentials of kolaviron: mechanisms of action
- Efficacy of oral vs. intratympanic corticosteroids in sudden sensorineural hearing loss
- Evaluation of antinociceptive and anti-inflammatory properties of methanolic crude extract of Lophopetalum javanicum (bark)
- Anti-nociceptive and anti-inflammatory effects of Withania somnifera root in fructose fed male rats
- Phytotherapy
- Biflavonoid fraction from Garcinia kola seed ameliorates hormonal imbalance and testicular oxidative damage by anti-tuberculosis drugs in Wistar rats
- Protective effect of Scutellaria species on AAPH-induced oxidative damage in human erythrocyte
- Miscellaneous
- Role of monocyte chemoattractant protein-1, stromal derived factor-1 and retinoic acid in pathophysiology of neuropathic pain in rats
- Hormonal and organ-specific dysfunction induced by the interaction between titanium dioxide nanoparticles and salicylic acid in male mice
- Case Report
- Blood pressure variability and baroreflex sensitivity of a healthy male during cold pressor test that induced development of neurocardiogenic syncope
Articles in the same Issue
- Frontmatter
- Reviews
- Assessment of paediatric pain: a critical review
- Can genotype determine the sports phenotype? A paradigm shift in sports medicine
- Oxidative Stress
- Neuroprotective effect of Decalepis hamiltonii on cyclophosphamide-induced oxidative stress in the mouse brain
- Hydroxycitric acid ameliorates high-fructose-induced redox imbalance and activation of stress sensitive kinases in male Wistar rats
- Metabolism
- Glucose absorption in the intestine of albino rats
- Inflammation
- Antinociceptive and anti-inflammatory potentials of kolaviron: mechanisms of action
- Efficacy of oral vs. intratympanic corticosteroids in sudden sensorineural hearing loss
- Evaluation of antinociceptive and anti-inflammatory properties of methanolic crude extract of Lophopetalum javanicum (bark)
- Anti-nociceptive and anti-inflammatory effects of Withania somnifera root in fructose fed male rats
- Phytotherapy
- Biflavonoid fraction from Garcinia kola seed ameliorates hormonal imbalance and testicular oxidative damage by anti-tuberculosis drugs in Wistar rats
- Protective effect of Scutellaria species on AAPH-induced oxidative damage in human erythrocyte
- Miscellaneous
- Role of monocyte chemoattractant protein-1, stromal derived factor-1 and retinoic acid in pathophysiology of neuropathic pain in rats
- Hormonal and organ-specific dysfunction induced by the interaction between titanium dioxide nanoparticles and salicylic acid in male mice
- Case Report
- Blood pressure variability and baroreflex sensitivity of a healthy male during cold pressor test that induced development of neurocardiogenic syncope
