Two Time Steps Predictive Control Application to a Bioprocess Simulator
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Semin Altuntaş
Semin Altuntaş is currently a senior expert of the Ministry of Environment and Urbanization. She holds a B.Sc., M.Sc. and Ph.D. from the Chemical Engineering Department of Ankara University, Turkey. She has written a number of articles on simulation and process control.
and
Hale Hapoglu
Hale Hapoglu is a professor in the Chemical Engineering Department, Ankara University, Turkey. She holds the B.Sc. and M.Sc. from the same department and a Ph.D. from the Chemical Engineering Department of Wales University, U.K. She has written over hundred articles on modelling, simulation and process control.
Abstract
The control of batch bioreactors to maintain the pH at a constant set point is quite different from the continuous system applications, because acid and base simultaneous addition has a strong effect on the closed-loop performance which may never reach the desired value. While it is most desirable to use approximate models based on the chemistry of the system, this may not always be possible for batch bioprocesses. The present paper discusses the usage of a simulator with appropriate input and output data obtained from the real batch bioprocess without control. The real process pH behaviour was simulated by using 7 M citric acid flow rate changes in the face of constant base addition. Two time steps predictive control was applied to the bioprocess simulator by coordinating 0.5 M citric acid and 0.5 M sodium bicarbonate flow rates. The best control weighting factor magnitude was determined. The control was achieved successfully for regulator problem.
About the authors
Semin Altuntaş is currently a senior expert of the Ministry of Environment and Urbanization. She holds a B.Sc., M.Sc. and Ph.D. from the Chemical Engineering Department of Ankara University, Turkey. She has written a number of articles on simulation and process control.
Hale Hapoglu is a professor in the Chemical Engineering Department, Ankara University, Turkey. She holds the B.Sc. and M.Sc. from the same department and a Ph.D. from the Chemical Engineering Department of Wales University, U.K. She has written over hundred articles on modelling, simulation and process control.
Acknowledgments
Financial support from Ankara University Scientific Research Projects Coordination Unit is gratefully acknowledged.
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Articles in the same Issue
- Special Section for Selected Papers from the First International Food Operations & Processing Simulation Workshop – FoodOPS2016
- Special Issue “Selected Papers from the First International Food Operations & Processing Simulation Workshop – FoodOPS2016 (September 26–28, 2016, Larnaca, Cyprus)”
- Simulation Model of a Production Facility of Agaricus bisporus Mycelium for Decision-Making Support
- Modeling and Simulation of Nitrogen Injection in Olive Oil
- CFD Simulation of a Co-rotating Twin-screw Extruder: Validation of a Rheological Model for a Starch-Based Dough for Snack Food
- Two Time Steps Predictive Control Application to a Bioprocess Simulator
- Modeling Thin Layer Drying Kinetics, Moisture Diffusivity and Activation Energy of Hazelnuts during Microwave-Convective Drying
- Design and Testing of an Augmented Reality Solution to Enhance Operator Safety in the Food Industry
- Research Articles
- Effect of Osmotic Pre-treatment and Temperature Storage Conditions on Water Activity and Colour of Dried Apple
- Study on Mechanical Properties for Shearing Breakage of Oat Kernel
- Development and Characterization of a Novel Ecofriendly Biodegradable Whey Protein Concentrate Film with nano-SiO2
- Effect of Drying on the Bioactive Compounds and Antioxidant Activity of Rubus lambertianus
