Home Optimized Modular Design and Experiment for Staggered Herringbone Chaotic Micromixer
Article
Licensed
Unlicensed Requires Authentication

Optimized Modular Design and Experiment for Staggered Herringbone Chaotic Micromixer

  • Xueye Chen EMAIL logo and Xiaolei Wang
Published/Copyright: March 12, 2015
Become an author with De Gruyter Brill
Submit Manuscript Author Information
International Journal of Chemical Reactor Engineering
From the journal International Journal of Chemical Reactor Engineering Volume 13 Issue 3

Abstract

The staggered herringbone chaotic micromixer has been designed based on the use of modular method and orthogonal experiment. With the modular method, the geometry of the micromixer was divided into straight channels and mixing units alternately. The mixing units were designed with orthogonal experiment. The aspect ratio of the herringbone to the microchannel (r1), the ratio of the width of herringbone to the spacing of between adjacent two herringbones (r2) and the width of the herringbone (r3) were investigated. The optimal outputs were r1 = 1:3, r2 = 1:1, and r3 = 50 µm. The micromixer was fabricated with two steps lithography method based on the presented optimal parameters, and the material of the micromixer was polydimethylsiloxane (PDMS). The optimized design method is proven to be an effective way for rapid design of the staggered herringbone chaotic micromixer.

Keywords: micromixer; design of experiments; optimal design; lithography

Funding statement: Funding: This work was supported by National Natural Science Foundation of China (51405214), Liaoning Province Doctor Startup Fund (20141131), Fund of Liaoning Province Education Administration (L2014241), and the Fund in Liaoning University of Technology (X201301).

References

1. MatsunagaT, LeeHJ, NishinoK. An approach for accurate simulation of liquid mixing in a T-shaped micromixer . Lab Chip2013;13:1515–21.10.1039/c3lc41009aSearch in Google Scholar PubMed

2. ViktorovV, NimafarM. A novel generation of 3D SAR-based passive micromixer: efficient mixing and low pressure drop at a low Reynolds number . J Micromech Microeng2013;23:5523–31.10.1088/0960-1317/23/5/055023Search in Google Scholar

3. BeardDA. Taylor dispersion of a solute in a microfluidic channel . J Appl Phys2001;89:4667–9.10.1063/1.1357462Search in Google Scholar

4. SongHJ, WangY, PantK. Cross-stream diffusion under pressure-driven flow in microchannels with arbitrary aspect ratios: a phase diagram study using a three-dimensional analytical model . Microfluid Nanofluid2012;12:265–77.10.1007/s10404-011-0870-xSearch in Google Scholar PubMed PubMed Central

5. StroockAD, DertingerSK, AjdariA, MezicI, StoneHA, WhitesidesGM. Chaotic mixer for microchannels . Science2002;295:647–51.10.1126/science.1066238Search in Google Scholar PubMed

6. WilliamsMS, LongmuirKJ, YagerP. A practical guide to the staggered herringbone mixer . Lab Chip2008;8:1121–9.10.1039/b802562bSearch in Google Scholar PubMed PubMed Central

7. WangLL, YangJT, LyuPC. An overlapping crisscross micromixer . Chem Eng Sci2007;62:711–20.10.1016/j.ces.2006.09.048Search in Google Scholar

8. SinghMK, KangTG, MeijerHE, AndersonPD. The mapping method as a toolbox to analyze, design, and optimize micromixers . Microfluid Nanofluidics2008;12:313–25.10.1007/s10404-007-0251-7Search in Google Scholar

9. KangTG, SinghMK, KwonTH, AndersonPD. Chaotic mixing using periodic and aperiodic sequences of mixing protocols in a micromixer . Microfluid Nanofluid2008;12:589–99.10.1007/s10404-007-0206-zSearch in Google Scholar

10. LiX, van der SteenG, van DedemGWK, van derWielenLAA, van GulikWM, HeijnenJJ, OttensM, KrommenhoekEE, GardeniersJGE, BergA. Application of direct fluid flow oscillations to improve mixing in microbioreactors . AIChE J2009;55:2725–36.10.1002/aic.11880Search in Google Scholar

11. Pilá ParkC, Awatará MauryaR, Haná LeeJ. Efficient photosensitized oxygenations in phase contact enhanced microreactors . Lab Chip2011;11:1941–5.10.1039/c1lc20071bSearch in Google Scholar PubMed

12. Tran-MinhN, KarlsenF, DongTA. Simple and low cost micromixer for laminar blood mixing: design, optimization, and analysis/biomedical informatics and technology. Berlin: Springer, 2014:91–104.Search in Google Scholar

13. SubramaniamK, ChakrabortyS. A semi-analytical model for species transport in combined electroosmotic and pressure driven microflows with surface adsorption-desorption reactions . Microfluid Nanofluid2011;10:821–9.10.1007/s10404-010-0713-1Search in Google Scholar

14. Cortes-QuirozCA, ZangenehM, GotoA. On multi-objective optimization of geometry of staggered herringbone micromixer . Microfluid Nanofluid2009;7:29–43.10.1007/s10404-008-0355-8Search in Google Scholar

15. Cortes-QuirozCA, AzarbadeganA, ZangenehM, GotoA. Analysis and multi-criteria design optimization of geometric characteristics of grooved micromixer . Chem Eng J2010;160:852–64.10.1016/j.cej.2010.02.029Search in Google Scholar

16. ChenXY, LiuC, XuZ, LiuJS, DuLQ. Macro-micro modeling design in system-level and experiment for a micromixer . Anal Methods2012;4:2334–40.10.1039/c2ay25263eSearch in Google Scholar

17. EricksonD, LiDQ. Influence of surface heterogeneity on electrokinetically driven microfluidic mixing . Langmuir2002;18:1883–92.10.1021/la015646zSearch in Google Scholar

Published Online: 2015-3-12
Published in Print: 2015-9-1

©2015 by De Gruyter

Articles in the same Issue

  1. Frontmatter
  2. Reviews
  3. Fischer–Tropsch Synthesis in Slurry Bubble Column Reactors: Experimental Investigations and Modeling – A Review
  4. Computational Fluid Dynamics-Based Hydrodynamics Studies in Packed Bed Columns: Current Status and Future Directions
  5. Research Articles
  6. Optimized Modular Design and Experiment for Staggered Herringbone Chaotic Micromixer
  7. Effects of the Types and Addition Amounts of Sludge on the True Rheological Properties of Petroleum Coke Slurry Flowing in Pipelines
  8. Stabilization of Fast Pyrolysis Oil Derived from Wood through Esterification
  9. CO2 Sorption by Hydrotalcite-Like Compounds in Dry and Wet Conditions
  10. Experimental Tests with Rice Straw on a Conical Square-Based Spouted Bed Reactor
  11. Kinetics for an Optimized Biosynthesis of Silver Nanoparticles Using Alfalfa Extracts
  12. Assessing the Feasibility of Optical Probe in Phase Holdup Measurements and Flow Regime Identification
  13. Modeling Study of Crude Oil Enhanced Removal in a Two-Liquid Phase Partitioning Bioreactor
  14. Application of Deep Eutectic Solvent (DES) as a Reaction Media for the Esterification of Acrylic Acid with n-Butanol
  15. Transesterification of Degummed Jatropha curcas Oil Using Tri-potassium Phosphate as Base Catalyst
  16. Process Intensification for Production of Ethyl Lactate from Fermentation-Derived Magnesium Lactate: A Preliminary Design
  17. A Study on the Production of Isophthalic Acid from M-xylene under the Catalysis of Cobalt and H3PW12O40/Carbon Modified by HNO3 Solution
  18. Statistical Medium Optimization for the Increased Production of Recombinant Phytase in the Fed-Batch Cultivation of Pichia pastoris
  19. Catalytic Degradation of Pyrrole in Aqueous Solution by Cu/SBA-15
https://doi.org/10.1515/ijcre-2014-0123
Keywords for this article
micromixer; design of experiments; optimal design; lithography

Articles in the same Issue

  1. Frontmatter
  2. Reviews
  3. Fischer–Tropsch Synthesis in Slurry Bubble Column Reactors: Experimental Investigations and Modeling – A Review
  4. Computational Fluid Dynamics-Based Hydrodynamics Studies in Packed Bed Columns: Current Status and Future Directions
  5. Research Articles
  6. Optimized Modular Design and Experiment for Staggered Herringbone Chaotic Micromixer
  7. Effects of the Types and Addition Amounts of Sludge on the True Rheological Properties of Petroleum Coke Slurry Flowing in Pipelines
  8. Stabilization of Fast Pyrolysis Oil Derived from Wood through Esterification
  9. CO2 Sorption by Hydrotalcite-Like Compounds in Dry and Wet Conditions
  10. Experimental Tests with Rice Straw on a Conical Square-Based Spouted Bed Reactor
  11. Kinetics for an Optimized Biosynthesis of Silver Nanoparticles Using Alfalfa Extracts
  12. Assessing the Feasibility of Optical Probe in Phase Holdup Measurements and Flow Regime Identification
  13. Modeling Study of Crude Oil Enhanced Removal in a Two-Liquid Phase Partitioning Bioreactor
  14. Application of Deep Eutectic Solvent (DES) as a Reaction Media for the Esterification of Acrylic Acid with n-Butanol
  15. Transesterification of Degummed Jatropha curcas Oil Using Tri-potassium Phosphate as Base Catalyst
  16. Process Intensification for Production of Ethyl Lactate from Fermentation-Derived Magnesium Lactate: A Preliminary Design
  17. A Study on the Production of Isophthalic Acid from M-xylene under the Catalysis of Cobalt and H3PW12O40/Carbon Modified by HNO3 Solution
  18. Statistical Medium Optimization for the Increased Production of Recombinant Phytase in the Fed-Batch Cultivation of Pichia pastoris
  19. Catalytic Degradation of Pyrrole in Aqueous Solution by Cu/SBA-15
Sign up now to receive a 20% welcome discount
Institutional Access
How does access work?
Have an idea on how to improve our website?
Please write us.
© 2025 De Gruyter Brill
Downloaded on 20.9.2025 from https://www.degruyterbrill.com/document/doi/10.1515/ijcre-2014-0123/html?lang=en
Scroll to top button