Microwave characterization of aqueous amino acid solutions using the multifrequency WGM resonator technique
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Alexey I. Gubin
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Alexander A. Lavrinovich
Abstract
Amino acids play essential role for humans. We studied the dielectric properties of the basic aliphatic amino acids and polar positive amino acids in solutions of different concentrations. The high-Q single microwave whispering gallery-mode (WGM) quartz dielectric resonator based technique, enhanced to a number of measurement frequencies, was applied. The technique allows liquid investigation of micro- to nano- liter volumes filled in microfluidic channel on six discrete frequencies in the 30–40 GHz range. The dependencies of the complex permittivity on the molar mass show almost linear behavior for aliphatic amino acids at different concentrations. The study results are in good agreement with the calculated data obtained by Cole-Cole equation.
Funding source: Deutsche Forschungsgemeinschaft
Award Identifier / Grant number: VI 456/4
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Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
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Research funding: The authors would like to thank the German Research Foundation (DFG), project VI 456/4, for their financial support.
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Conflict of interest statement: The authors declare no conflicts of interest regarding this article.
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Articles in the same Issue
- Frontmatter
- Highlight: Structure and Function of the Peroxisomal Translocon
- Highlight: structure and function of the peroxisomal translocon
- Super-resolution microscopy and studies of peroxisomes
- Good things come to those who bait: the peroxisomal docking complex
- Determining the targeting specificity of the selective peroxisomal targeting factor Pex9
- Phosphorylation of the receptor protein Pex5p modulates import of proteins into peroxisomes
- Membrane binding and pore forming insertion of PEX5 into horizontal lipid bilayer
- Dynamics of the translocation pore of the human peroxisomal protein import machinery
- Distinct conformational and energetic features define the specific recognition of (di)aromatic peptide motifs by PEX14
- Asymmetric horseshoe-like assembly of peroxisomal yeast oxalyl-CoA synthetase
- Comparison of human PEX knockout cell lines suggests a dual role of PEX1 in peroxisome biogenesis
- Research Articles/Short Communications
- Proteolysis
- Investigation of the P1′ and P2′ sites of IQF substrates and their selectivity toward 20S proteasome subunits
- Novel Techniques
- Microwave characterization of aqueous amino acid solutions using the multifrequency WGM resonator technique
- Corrigendum
- Corrigendum to: determination of free heme in stored red blood cells with an apo-horseradish peroxidase-based assay
