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How to build the fastest receptor on earth

  • Jelena Baranovic and Andrew J.R. Plested ORCID logo EMAIL logo
Published/Copyright: August 31, 2015

Abstract

In 2014, a slew of structures of glutamate receptors were published, based on crystallography and electron microscopy. Here we review these insights, integrate them with existing knowledge about receptor function and try to understand how the structures relate to the key property of the AMPA receptor – its speed.


Corresponding author: Andrew J.R. Plested, Leibniz Institut für Molekulare Pharmakologie (FMP), Robert-Rössle-Str. 10, D-13125 Berlin, Germany; and NeuroCure, Charité-Universitätsmedizin, Charitéplatz 1, D-10117, Berlin, Germany, e-mail: .

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Received: 2015-5-23
Accepted: 2015-8-27
Published Online: 2015-8-31
Published in Print: 2016-3-1

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