Ectopic adrenal tissue associated with borderline mucinous cystadenoma of ovary: a case report with review of the literature
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Kah Teik Chew
, Muhammad Azrai Abu
, Yulianty Arifuddin
, Nor Azlin Mohamed Ismail , Noor Ain Mohd Nasir , Fazarina Mohammed and Abdul Ghani Nur Azurah
Abstract
Ectopic adrenal tissue in the ovary is a rare entity. We reported a case of ectopic adrenal tissue in borderline mucinous cystadenoma of the left ovary. A 22 year-old student presented with progressive abdomen distension associated with discomfort for 3 months. Imaging investigation was suggestive of mucinous left ovarian cyst. Left salpingo-oophorectomy was performed and the histopathology revealed borderline mucinous cystadenoma with an incidental finding of ectopic adrenal tissue. This is an interesting case because of its rarity and potential risk of neoplasm changes.
Author statement
Research funding: Authors state no funding involved.
Conflict of interest: The authors declare no conflict of interest. All authors are responsible for the content and writing of this paper.
Informed consent: Informed consent was obtained from the patient for publication of this case report.
Ethical approval: Ethical approval was not applicable.
References
[1] Schechter DC. Aberrant adrenal tissue. Ann Surg. 1968;167:421–6.10.1097/00000658-196803000-00017Search in Google Scholar
[2] Mendez R, Tellado MG, Somoza I, Liras J, Sanchez-Abuin A, Pais E, et al. Ectopic adrenal tissue in the spermatic cord in pediatric patients: surgical implications. Int Braz J Urol. 2006;32:202–7.10.1590/S1677-55382006000200013Search in Google Scholar
[3] Barwick T, Malhotra A, Webb J, Savage M, Reznek R. Embryology of the adrenal glands and its relevance to diagnostic imaging. Clin Radiol. 2005;60:953–9.10.1016/j.crad.2005.04.006Search in Google Scholar
[4] Anderson J, Ross AM. Ectopic adrenal tissue in adults. Postgrad Med J. 1980;56:806–8.10.1136/pgmj.56.661.806Search in Google Scholar
[5] Graham L. Celiac accessory adrenal glands. Cancer. 1953;6:149–52.10.1002/1097-0142(195301)6:1<149::AID-CNCR2820060115>3.0.CO;2-8Search in Google Scholar
[6] Sasano H, Sato S, Yajima A, Akarna J, Nagura H. Adrenal rest tumor of the broad ligament: case report with immunohistochemical study of steroidogenic enzymes. Pathol Int. 1997;47:493–6.10.1111/j.1440-1827.1997.tb04529.xSearch in Google Scholar
[7] Khandakar B, Dey S, Ray PS, Sarkar R, Bhattacharyya P. Ectopic paratubal adrenal cell rest associated with mucinous cystadenoma of ovary. J Clin Diagn Res. 2015;ED139.10.7860/JCDR/2015/15411.6638Search in Google Scholar
[8] Yasar L, Ekin M, Kaya C, Ozkan Y. A rare case of ectopic adrenal tissue in the left ovary in a patient with a granulosa-cell tumor of the right ovary. J Gynecol Surg. 2012;28:220–2.10.1089/gyn.2011.0055Search in Google Scholar
[9] Usta U, Türkmen E, Aydın NE. Adrenal ectopia within the wall of an ovarian serous cystadenoma. Balkan Med J. 2006;23:95–98.Search in Google Scholar
[10] Kasajima A, Nakamura Y, Adachi Y, Takahashi Y, Fujishima F, Chiba Y, et al. Oncocytic adrenocortical neoplasm arising from adrenal rest in the broad ligament of the uterus. Pathol Int. 2014;64:183–8.10.1111/pin.12154Search in Google Scholar
[11] Şahin Ç, Taylan E, Akdemir A, Zekioglu O, Seyidova P, Ergenoglu AM. Ovarian serous cystadenoma with ectopic adrenal tissue in a 65-year-old patient: a case report. Int J Surg Case Rep. 2017;33:89–91.10.1016/j.ijscr.2017.02.045Search in Google Scholar
[12] Savaş Ç, Çandır Ö, Bezir M, Çakmak M. Ectopic adrenocortical nodules along the spermatic cord of children. Int Urol Nephrol. 2001;32:681–5.10.1023/A:1014429119226Search in Google Scholar
[13] Shappell HW, Riopel MA, Sehdev AE, Ronnett BM, Kurman RJ. Diagnostic criteria and behavior of ovarian seromucinous (endocervical-type mucinous and mixed cell-type) tumors: atypical proliferative (borderline) tumors, intraepithelial, microinvasive, and invasive carcinomas. Am J Surg Pathol. 2002;26:1529–41.10.1097/00000478-200212000-00001Search in Google Scholar PubMed
[14] du Bois Ad, Ewald-Riegler N, Du Bois O, Harter P. Borderline tumors of the ovary-a systematic review. Geburtshilfe und Frauenheilkunde. 2009;69:807–33.10.1055/s-0029-1186007Search in Google Scholar
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- Review Articles
- Tumor-linked HER2 expression: association with obesity and lipid-related microenvironment
- The functional significance of 14-3-3 proteins in cancer: focus on lung cancer
- Original Articles
- The effect of thyroid dysfunction on nesfatin-1 and adiponectin levels in rats
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- Do exercises improve back pain in pregnancy?
- Case Report
- Ectopic adrenal tissue associated with borderline mucinous cystadenoma of ovary: a case report with review of the literature