Abstract
The prevalence of overweight and obesity in women of reproductive age has increased over the past 30 years. Infertility affects 1 in 7 couples, and female obesity is associated with anovulation. The mechanisms by which excessive fat delays time to pregnancy (TTP) appear rooted in ovulatory problems and direct effects on oocytes, causing poorer embryo development, as well as in effects on the endometrium. Weight loss in women has been shown to improve conception, but not necessarily live birth rates following fertility treatment, and further research in this area is needed. The obesity epidemic has been accompanied by a potential rise in male infertility, which has been attributed to hormonal disturbances and compromised semen parameters.
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©2015 by De Gruyter
Articles in the same Issue
- Frontmatter
- Editorial Preface
- Preface to special issue on Peripheral and Central Control of Human Reproduction: Endocrine Aspects – Part 1
- Topic A: Impact of Obesity/Adiposity and Adipokines on Reproduction, Fertility and Pregnancy
- Review Articles
- Obesity and fertility
- Adipokines in human reproduction
- Roles of leptin, adiponectin and resistin in the transcriptional regulation of steroidogenic genes contributing to decreased Leydig cells function in obesity
- The roles of leptin and adiponectin at the fetal-maternal interface in humans
- Endocrine and metabolic adaptations to pregnancy; impact of obesity
Articles in the same Issue
- Frontmatter
- Editorial Preface
- Preface to special issue on Peripheral and Central Control of Human Reproduction: Endocrine Aspects – Part 1
- Topic A: Impact of Obesity/Adiposity and Adipokines on Reproduction, Fertility and Pregnancy
- Review Articles
- Obesity and fertility
- Adipokines in human reproduction
- Roles of leptin, adiponectin and resistin in the transcriptional regulation of steroidogenic genes contributing to decreased Leydig cells function in obesity
- The roles of leptin and adiponectin at the fetal-maternal interface in humans
- Endocrine and metabolic adaptations to pregnancy; impact of obesity