Abstract
Nearly a decade after the National Academy of Medicine released the “Improving Diagnosis in Health Care” report, diagnostic errors remain common, often leading to physical, psychological, emotional, and financial harm. Despite a robust body of research on potential solutions and next steps, the translation of these efforts to patient care has been limited. Improvement initiatives are still narrowly focused on selective themes such as diagnostic stewardship, preventing overdiagnosis, and enhancing clinical reasoning without comprehensively addressing vulnerable systems and processes surrounding diagnosis. To close this implementation gap, the US Centers for Disease Control and Prevention (CDC) released the Core Elements of Hospital Diagnostic Excellence programs on September 17, 2024. This initiative aligns with the World Health Organization’s (WHO) 2024 World Patient Safety Day focus on improving diagnosis. These Core Elements provide guidance for the formation of hospital programs to improve diagnosis and aim to integrate various disparate efforts in hospitals. By creating a shared mental model of diagnostic excellence, the Core Elements of Diagnostic Excellence supports actions to break down silos, guide hospitals toward multidisciplinary diagnostic excellence teams, and provide a foundation for building diagnostic excellence programs in hospitals.
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Research ethics: Not applicable.
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Informed consent: Not applicable.
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Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
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Use of Large Language Models, AI and Machine Learning Tools: Not declared.
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Conflict of interest: (All outside the submitted work). All authors contributed to the development of the Core Elements. Dr. Morgan is funded by the Veterans Administration (VA) Health Services Research (HSR), the Agency for Healthcare Research and Quality, and the Centers for Disease Control and Prevention. Dr. Singh is funded by the Houston Veterans Administration (VA) Health Services Research and Development (HSR&D) Center for Innovations in Quality, Effectiveness, and Safety (CIN13–413), the VA National Center for Patient Safety, and the Agency for Healthcare Research and Quality (R01HS028595 and R18HS029347). Dr. Bradford is supported by grant no. 1R01HS029318-01A1 from the Agency for Healthcare Research and Quality. Drs. Srinivasan, McDonald, and Kutty – none reported.
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Research funding: None declared.
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Data availability: Not applicable.
References
1. Committee on Diagnostic Error in Health Care, Board on Health Care Services, Institute of Medicine, The National Academies of Sciences, Engineering, and Medicine. Improving diagnosis in health care, Balogh, EP, Miller, BT, Ball, JR, editors. National Academies Press (US); 2015. http://www.ncbi.nlm.nih.gov/books/NBK338596/ [Accessed 14 Aug 2024].Search in Google Scholar
2. Khan, S, Cholankeril, R, Sloane, J, Offner, A, Sittig, DF, Bradford, A, et al.. Current state of diagnostic safety: implications for research, practice, and policy. Rockville, MD: Agency for Healthcare Research and Quality; 2024.Search in Google Scholar
3. CDC. Core elements of hospital diagnostic excellence (DxEx). Patient safety; 2024. https://www.cdc.gov/patient-safety/hcp/hospital-dx-excellence/index.html [Accessed 15 Oct 2024].Search in Google Scholar
4. World patient safety day, 17 September 2024: “improving diagnosis for patient safety.” https://www.who.int/news-room/events/detail/2024/09/17/default-calendar/world-patient-safety-day-17-september-2024-improving-diagnosis-for-patient-safety [Accessed 15 Oct 2024].Search in Google Scholar
5. Centers for Disease Control and Prevention. The core elements of hospital antibiotic stewardship programs; 2019. Published online 2019. https://www.cdc.gov/antibiotic-use/core-elements/hospital.html [Accessed 17 May 2022].Search in Google Scholar
6. Hospital sepsis program Core Elements | sepsis | CDC. 2024. https://www.cdc.gov/sepsis/core-elements.html [Accessed 5 Feb 2024].Search in Google Scholar
7. Antibiotic stewardship. https://www.jointcommission.orghttps://www.jointcommission.org/resources/patient-safety-topics/infection-prevention-and-control/antibiotic-stewardship/ [Accessed 15 Oct 2024].Search in Google Scholar
8. Fabre, V, Davis, A, Diekema, DJ, Granwehr, B, Hayden, MK, Lowe, CF, et al.. Principles of diagnostic stewardship: a practical guide from the society for healthcare epidemiology of America diagnostic stewardship task force. Infect Control Hosp Epidemiol 2023;44:178–85. https://doi.org/10.1017/ice.2023.5.Search in Google Scholar PubMed
9. Brodersen, J, Schwartz, LM, Heneghan, C, O’Sullivan, JW, Aronson, JK, Woloshin, S. Overdiagnosis: what it is and what it isn’t. BMJ Evid Based Med 2018;23:1–3. https://doi.org/10.1136/ebmed-2017-110886.Search in Google Scholar PubMed
10. Giardina, TD, Shahid, U, Mushtaq, U, Upadhyay, DK, Marinez, A, Singh, H. Creating a learning health system for improving diagnostic safety: pragmatic insights from US health care organizations. J Gen Intern Med 2022;37:3965–72. https://doi.org/10.1007/s11606-022-07554-w.Search in Google Scholar PubMed PubMed Central
11. Morgan, DJ, Malani, PN, Diekema, DJ. Diagnostic stewardship to prevent diagnostic error. JAMA 2023;1255–6. https://doi.org/10.1001/jama.2023.1678.Search in Google Scholar PubMed
12. Recognizing excellence in diagnosis. Leapfrog. 2021. https://www.leapfroggroup.org/influencing/recognizing-excellence-diagnosis [Accessed 15 Oct 2024].Search in Google Scholar
© 2024 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Frontmatter
- Editorial
- Pioneering diagnosis in Asia: advancing clinical reasoning expertise through the lens of 3M
- Short Communication
- The foundations of the diagnostic error movement: a tribute to Eta Berner, PhD
- Reviews
- Interventions to improve timely cancer diagnosis: an integrative review
- Technical aspects and clinical applications of synthetic MRI: a scoping review
- Mini Review
- Challenges and barriers for the adoption of personalized medicine in Europe: the case of Oncotype DX Breast Recurrence Score® test
- Opinion Papers
- Beyond thinking fast and slow: a Bayesian intuitionist model of clinical reasoning in real-world practice
- Diagnostic scope: the AI can’t see what the mind doesn’t know
- Guidelines and Recommendations
- CDC’s Core Elements to promote diagnostic excellence
- Original Articles
- Trends of diagnostic adverse events in hospital deaths: longitudinal analyses of four retrospective record review studies
- The effect of a provisional diagnosis on intern diagnostic reasoning: a mixed methods study
- On context specificity and management reasoning: moving beyond diagnosis
- Diagnostic errors in patients admitted directly from new outpatient visits
- Breaking the guidelines: how financial unawareness fuels guideline deviations and inefficient DVT diagnostics
- Harbingers of sepsis misdiagnosis among pediatric emergency department patients
- Factors affecting diagnostic difficulties in aseptic meningitis: a retrospective observational study
- Prenatal diagnostic errors in hemoglobin Bart’s hydrops fetalis caused by rare genetic interactions of α-thalassemia
- Screening fasting glucose before the OGTT: near-patient glucometer- or laboratory-based measurement?
- Three-way comparison of different ESR measurement methods and analytical performance assessment of TEST1 automated ESR analyzer
- Short Communications
- Medical language matters: impact of clinical summary composition on a generative artificial intelligence’s diagnostic accuracy
- Impact of meta-memory techniques in generating effective differential diagnoses in a pediatric core clerkship
Articles in the same Issue
- Frontmatter
- Editorial
- Pioneering diagnosis in Asia: advancing clinical reasoning expertise through the lens of 3M
- Short Communication
- The foundations of the diagnostic error movement: a tribute to Eta Berner, PhD
- Reviews
- Interventions to improve timely cancer diagnosis: an integrative review
- Technical aspects and clinical applications of synthetic MRI: a scoping review
- Mini Review
- Challenges and barriers for the adoption of personalized medicine in Europe: the case of Oncotype DX Breast Recurrence Score® test
- Opinion Papers
- Beyond thinking fast and slow: a Bayesian intuitionist model of clinical reasoning in real-world practice
- Diagnostic scope: the AI can’t see what the mind doesn’t know
- Guidelines and Recommendations
- CDC’s Core Elements to promote diagnostic excellence
- Original Articles
- Trends of diagnostic adverse events in hospital deaths: longitudinal analyses of four retrospective record review studies
- The effect of a provisional diagnosis on intern diagnostic reasoning: a mixed methods study
- On context specificity and management reasoning: moving beyond diagnosis
- Diagnostic errors in patients admitted directly from new outpatient visits
- Breaking the guidelines: how financial unawareness fuels guideline deviations and inefficient DVT diagnostics
- Harbingers of sepsis misdiagnosis among pediatric emergency department patients
- Factors affecting diagnostic difficulties in aseptic meningitis: a retrospective observational study
- Prenatal diagnostic errors in hemoglobin Bart’s hydrops fetalis caused by rare genetic interactions of α-thalassemia
- Screening fasting glucose before the OGTT: near-patient glucometer- or laboratory-based measurement?
- Three-way comparison of different ESR measurement methods and analytical performance assessment of TEST1 automated ESR analyzer
- Short Communications
- Medical language matters: impact of clinical summary composition on a generative artificial intelligence’s diagnostic accuracy
- Impact of meta-memory techniques in generating effective differential diagnoses in a pediatric core clerkship