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Atrial fibrillation: is there a role for cardiac troponin?

  • Alireza Sepehri Shamloo ORCID logo EMAIL logo , Arash Arya , Angeliki Darma , Sotirios Nedios , Michael Döring , Andreas Bollmann , Nikolaos Dagres and Gerhard Hindricks
Published/Copyright: January 9, 2020
Diagnosis
From the journal Diagnosis Volume 8 Issue 3

Abstract

Atrial fibrillation (AF) is the most common sustained arrhythmia, and its prevalence rate is expected to be doubled over the next decades. Despite the wide use of biomarkers in the management of different cardiac diseases such as myocardial infarction and heart failure, utilization of biomarkers in AF management is not routinely recommended by current guidelines. There is also growing evidence that higher levels of cardiac-specific troponin, as an intracellular protein involved in cardiomyocyte contraction, may be associated with the risk of incident and recurrent AF and its complications. In the present paper, we review the association between troponin and AF and propose clinical suggestions for use of troponin in the management of AF patients.

Keywords: atrial fibrillation; biomarker; risk score; troponin
Corresponding author: Alireza Sepehri Shamloo, MD, Department of Electrophysiology, Heart Center Leipzig at University of Leipzig, Strümpellstrasse 39, 04289 Leipzig, Germany, Phone: +49 341 8651413, Fax: +49 341 8651460

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: AB, ND, and GH report research grants from Abbott and Boston Scientific to the institution without personal financial benefits. Other authors do not declare any conflict of interest.

  3. Employment or leadership: None declared.

  4. Honorarium: None declared.

  5. Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.

  6. Conflict of interest statement: AB, ND, and GH report research grants from Abbott and Boston Scientific to the institution without personal financial benefits. Other authors do not declare any conflict of interest.

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Received: 2019-10-11
Accepted: 2019-12-06
Published Online: 2020-01-09
Published in Print: 2021-08-26

©2020 Walter de Gruyter GmbH, Berlin/Boston

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  2. Editorial
  3. Chest pain management and biomarkers: the lack of trust in cardiac troponins measurement
  4. Reviews
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  6. Atrial fibrillation: is there a role for cardiac troponin?
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  10. Guidelines and Recommendations
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https://doi.org/10.1515/dx-2019-0072
Keywords for this article
atrial fibrillation; biomarker; risk score; troponin

Articles in the same Issue

  1. Frontmatter
  2. Editorial
  3. Chest pain management and biomarkers: the lack of trust in cardiac troponins measurement
  4. Reviews
  5. Bringing the clinical laboratory into the strategy to advance diagnostic excellence
  6. Atrial fibrillation: is there a role for cardiac troponin?
  7. Opinion Papers
  8. Towards better metainterpretation: improving the clinician’s interpretation of the radiology report
  9. The challenges of diagnosing diabetes in childhood
  10. Guidelines and Recommendations
  11. Measuring patient experience of diagnostic care and acceptability of testing
  12. Original Articles
  13. Clinical assessment of the Roche SARS-CoV-2 rapid antigen test
  14. Delayed treatment of bacteremia during the COVID-19 pandemic
  15. Strengths and weaknesses in the diagnostic process of endometriosis from the patients’ perspective: a focus group study
  16. Identifying trigger concepts to screen emergency department visits for diagnostic errors
  17. Handshake antimicrobial stewardship as a model to recognize and prevent diagnostic errors
  18. Uncertain diagnoses in a children’s hospital: patient characteristics and outcomes
  19. The effects of rudeness, experience, and perspective-taking on challenging premature closure after pediatric ICU physicians receive hand-off with the wrong diagnosis: a randomized controlled simulation trial
  20. Resident-faculty overnight discrepancy rates as a function of number of consecutive nights during a week of night float
  21. CONUT: a tool to assess nutritional status. First application in a primary care population
  22. Is there a real need for sputum culture for community-acquired pneumonia diagnostics? Results from a retrospective study in Russia
  23. Differentiating solid breast masses: comparison of the diagnostic efficacy of shear wave elastography and magnetic resonance imaging
  24. Short Communication
  25. Chest pain management: use of troponins in internal medicine wards
  26. Case Report
  27. Learning from tragedy – The Jessica Barnett story: challenges in the diagnosis of long QT syndrome
  28. Letters to the Editor
  29. Usability of non-medicinal swabs for SARS-CoV-2 detection to circumvent supply shortages
  30. Medical decision making during the COVID-19 epidemic: an opportunity to think how we think
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