Macro-CK type 2 in metastatic prostate cancer
-
Abass Eidizadeh
,
Nicolas von Ahsen
Abstract
The isoenzyme creatine kinase muscle/brain (CK-MB) still plays an important role for the differential diagnosis of CK elevations and the clarification of their origin from heart or skeletal muscle. Therefore, it is necessary to know the diagnostic pitfalls in interpreting CK-MB results. We demonstrate a case of macro-CK type 2 in a 75-year-old patient with metastatic castration-resistant prostate cancer and its identification by isoenzyme electrophoresis, which can be typical for cancer diseases.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
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©2019 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
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- Original Articles
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- Letter to the Editor
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- Case Reports
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- Macro-CK type 2 in metastatic prostate cancer
Articles in the same Issue
- Frontmatter
- Editorial
- The Model List of Essential In Vitro Diagnostics: nuisance or opportunity?
- Reviews
- Skeletal myopathies as a non-cardiac cause of elevations of cardiac troponin concentrations
- Histo-genomics: digital pathology at the forefront of precision medicine
- Opinion Papers
- Patients as diagnostic collaborators: sharing visit notes to promote accuracy and safety
- Understanding the “philosophy” of laboratory hemostasis
- Original Articles
- Serious misdiagnosis-related harms in malpractice claims: The “Big Three” – vascular events, infections, and cancers
- Electronic health records, communication, and data sharing: challenges and opportunities for improving the diagnostic process
- Mortality and morbidity rounds (MMR) in pathology: relative contribution of cognitive bias vs. systems failures to diagnostic error
- Experienced physician descriptions of intuition in clinical reasoning: a typology
- A randomized experimental study to assess the effect of language on medical students’ anxiety due to uncertainty
- Development and application of a PCR-HRM molecular diagnostic method of SNPs linked with TNF inhibitor efficacy
- Acute rejection in kidney transplantation and the evaluation of associated polymorphisms (SNPs): the importance of sample size
- Letter to the Editor
- Physically damaged second victims by diagnostic delay in pulmonary tuberculosis of hospitalized patients. Cognitive errors with urgent need for prevention
- The physical examination, including point of care technology, is an important part of the diagnostic process and should be included in educational interventions to improve clinical reasoning
- Case Reports
- Case reports of diagnostic error: liposarcoma mistaken for hematoma in an obese female with concurrent ipsilateral thrombosis on rivaroxaban
- Macro-CK type 2 in metastatic prostate cancer
