Medication therapy management (MTM): an innovative approach to improve medication adherence in diabetics
-
Athira Bindu Murali
, Belsy Boban
, Aswathy Karoor Shanmughan , Karthikeyan Marimuthu, Aravind Ramakrishnan Sreelatha
and Augustine Xavier
Abstract
Background:
Medication therapy management (MTM) is a pharmacist-led professional service, one of the main aims of which is to improve patient medication adherence. Ensuring adequate adherence to the prescribed therapeutic regimen is one of the major challenges in attaining the desired therapeutic goals in diabetics. The objective of this study was to implement MTM in diabetic patients and to identify its effectiveness in improving patient medication adherence.
Methods:
A prospective interventional study was carried out within a 1-year period in KIMS-Al-Shifa Hospital, which is a tertiary care referral hospital in Malabar region of Kerala, including inpatients with type 2 diabetes mellitus in the general medicine department of the hospital. The MTM programme was applied in selected patients, including personal medication record, medication-related action plan and detailed counselling. Adherence was measured using the Modified Morisky Medication Adherence Scale-4 both before and after the programme.
Results:
A total of 104 patients were included in the study. The adherence of patients to anti-diabetic therapy was very low, which showed significant improvement after applying intervention (p-value<0.05 in a paired t-test). Initially, only 37.5% had high adherence which was increased to 59.5% after intervention. Age and educational status were identified to have a significant impact on patient medication adherence (p-value<0.05 in a χ2-test).
Conclusions:
Medication adherence is a key component of self-management for patients with diabetes. A pharmacist-led MTM programme if appropriately designed and implemented will have a potential positive impact on medication adherence in diabetic patients.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
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- Original Articles
- Association study of DRD2 A2/A1, DRD3 Ser9Gly, DβH −1021C>T, OPRM1 A118G and GRIK1 rs2832407C>A polymorphisms with alcohol dependence
- Medication therapy management (MTM): an innovative approach to improve medication adherence in diabetics
- Pharmacogenetic approach to losartan in Marfan patients: a starting point to improve dosing regimen?
- Altered pharmacokinetics of rosiglitazone in a mouse model of non-alcoholic fatty liver disease
- The impact of CYP4F2, ABCB1, and GGCX polymorphisms on bleeding episodes associated with acenocoumarol in Russian patients with atrial fibrillation