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Symptomatic and lethal congenital primary cardiac rhabdomyoma

  • Mercedes Olaya-C ORCID logo EMAIL logo , Jorge Andres Franco and Oscar Alberto Messa
Published/Copyright: November 21, 2019
Case Reports in Perinatal Medicine
From the journal Case Reports in Perinatal Medicine Volume 9 Issue 1

Abstract

Background

Congenital tumors, including mesenchymal rhabdomyoma, are highly infrequent. The combination of a congenital tumor and rhabdomyoma is rarer yet, even more so when primary origin is in the heart.

Case presentation

We present a case of fetal hydrops fetalis, wherein the post-mortem exam revealed a cardiac tumor more than twice the size of the heart itself; histological study confirmed primary rhabdomyoma involving the left ventricle.

Conclusion

It is essential to keep in mind that fetal tumors should always be differentiated from malformations; in fetuses tissue immaturity must be taken into account for categorization; despite benign labeling, they can be lethal.

Keywords: Cardiac tumor; congenital tumor; rhabdomyoma; stillbirth

Acknowledgments

We thank the parents who authorized pathology studies and reports. We also extend our thanks to Steven W. Bayless for the English language text correction.

  1. Ethical approval: The research related to human use has complied with all the relevant national regulations, institutional policies and has been conducted in accordance with the tenets of the Helsinki Declaration, and it has been approved by the authors’ Institutional Review Board or equivalent committee.

  2. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  3. Research funding: None declared.

  4. Employment or leadership: None declared.

  5. Honorarium: None declared.

  6. Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.

  7. Informed consent: Informed consent was obtained from all individuals included in this study.

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Received: 2019-04-06
Accepted: 2019-08-31
Published Online: 2019-11-21

© 2020 Walter de Gruyter GmbH, Berlin/Boston

Articles in the same Issue

  1. Case Reports – Obstetrics
  2. Fetal pulmonary choristoma: report of first case and literature review
  3. Ultrasound prenatal diagnosis of a de novo 14q distal duplication associated with foetal anomalies: a case report
  4. Prenatal diagnosis of Kleefstra syndrome
  5. Cardiac implant and the risk of infective endocarditis in pregnancy
  6. Iatrogenic fetal goiter. Conservative management and spontaneous resolution
  7. Management in cases of large uterine myomas in pregnancy
  8. Significantly enlarged varix in the free-loop of the umbilical cord during the second trimester
  9. A case report of co-infection with rhinovirus and SARS-CoV-2 in pregnancy
  10. Monoamniotic twins pregnancy complicated by a fetal congenital heart defect – a challenge for perinatal decisions
  11. Favorable outcome after nine minutes of shoulder dystocia preceded by a tight nuchal cord
  12. Circumvallate placenta and abnormal cord insertion as risk factors for intrauterine growth restriction and preterm birth: a case report
  13. A rare case of intra-uterine blood transfusion for fetal anemia caused by a giant placental chorioangioma
  14. Septated fetal bladder in a case of 2q13 deletion
  15. A case of prenatal diagnosis of single umbilical artery due to thrombosis diagnosed by the ultrasound finding of “wink-sign”
  16. Ultrasound diagnosis of myelomeningocele: the role of 3D ultrasonography in determining surficial status of the pathological lesion
  17. Pragmatic approach and variations in the management of pregnant women with type 1 diabetes mellitus on insulin pump: a case series
  18. A great pre-eclampsia masquerader. Hemophagocytic lymphohistiocytosis (HLH) presenting in pregnancy
  19. Survival of both twins in a pregnancy complicated by pre-viable cord prolapse at 21 weeks of gestation
  20. A case report of a pregnant woman diagnosed with intrahepatic cholangiocarcinoma (ICC) complicated by opioid tolerance
  21. Prenatal and postnatal imaging of an intrapericardial teratoma
  22. Case report of a ruptured uterine sacculation in the 19th week of pregnancy
  23. Is thromboelastography reliable in postpartum coagulopathies? Two case reports and a literature review
  24. Prenatal diagnosis of megacystis-microcolon-intestinal hypoperistalsis syndrome
  25. Fetal head entrapment within the lower uterine segment
  26. Case Reports – Fetus
  27. A case of diprosopus: a rare form of twinning radiology-pathology correlation
  28. Case Reports – Newborn
  29. Transmission of SARS-CoV-2 to premature twins from an asymptomatic mother
  30. Spinal dysraphism, club feet, and dextrocardia with situs inversus totalis in a neonate: a rare association and review
  31. Giant congenital vascular malformation: diagnostic approach and clinical course
  32. Transient neonatal myasthenia gravis following maternal myasthenia gravis presenting in pregnancy after treatment with Alemtuzumab
  33. Congenital pulmonary lymphangiectasia in an extremely low birth weight: a case report
  34. Congenital kaposiform hemangioendothelioma: don’t let the appearances fool you
  35. Agnathia-otocephaly complex: a case report and a literature review on recurrence risk
  36. Perinatal severe hypophosphatasia: a case report
  37. Recurrent neonatal group B streptococcus cellulitis and adenitis syndrome with late-onset sepsis
  38. Neonatal hypertension caused by left-to-right shunt flow through a patent ductus arteriosus in a premature infant
  39. Maternal Babesia infection associated with neonatal extramedullary hematopoiesis and acute myeloid leukemia in late infancy
  40. Congenital high airway obstruction syndrome complicated with foregut malformation and high airway fistula to the alimentary tract – a case series with four distinct types
  41. Aplasia cutis congenita as a consequence of fetal reduction in a triplet pregnancy
  42. Anhydramnios, but prenatally normal kidneys: renal tubular dysgenesis – patient with mutations in the renin-angiotensin system gene AGTR1
  43. Symptomatic and lethal congenital primary cardiac rhabdomyoma
https://doi.org/10.1515/crpm-2019-0024
Keywords for this article
Cardiac tumor; congenital tumor; rhabdomyoma; stillbirth

Articles in the same Issue

  1. Case Reports – Obstetrics
  2. Fetal pulmonary choristoma: report of first case and literature review
  3. Ultrasound prenatal diagnosis of a de novo 14q distal duplication associated with foetal anomalies: a case report
  4. Prenatal diagnosis of Kleefstra syndrome
  5. Cardiac implant and the risk of infective endocarditis in pregnancy
  6. Iatrogenic fetal goiter. Conservative management and spontaneous resolution
  7. Management in cases of large uterine myomas in pregnancy
  8. Significantly enlarged varix in the free-loop of the umbilical cord during the second trimester
  9. A case report of co-infection with rhinovirus and SARS-CoV-2 in pregnancy
  10. Monoamniotic twins pregnancy complicated by a fetal congenital heart defect – a challenge for perinatal decisions
  11. Favorable outcome after nine minutes of shoulder dystocia preceded by a tight nuchal cord
  12. Circumvallate placenta and abnormal cord insertion as risk factors for intrauterine growth restriction and preterm birth: a case report
  13. A rare case of intra-uterine blood transfusion for fetal anemia caused by a giant placental chorioangioma
  14. Septated fetal bladder in a case of 2q13 deletion
  15. A case of prenatal diagnosis of single umbilical artery due to thrombosis diagnosed by the ultrasound finding of “wink-sign”
  16. Ultrasound diagnosis of myelomeningocele: the role of 3D ultrasonography in determining surficial status of the pathological lesion
  17. Pragmatic approach and variations in the management of pregnant women with type 1 diabetes mellitus on insulin pump: a case series
  18. A great pre-eclampsia masquerader. Hemophagocytic lymphohistiocytosis (HLH) presenting in pregnancy
  19. Survival of both twins in a pregnancy complicated by pre-viable cord prolapse at 21 weeks of gestation
  20. A case report of a pregnant woman diagnosed with intrahepatic cholangiocarcinoma (ICC) complicated by opioid tolerance
  21. Prenatal and postnatal imaging of an intrapericardial teratoma
  22. Case report of a ruptured uterine sacculation in the 19th week of pregnancy
  23. Is thromboelastography reliable in postpartum coagulopathies? Two case reports and a literature review
  24. Prenatal diagnosis of megacystis-microcolon-intestinal hypoperistalsis syndrome
  25. Fetal head entrapment within the lower uterine segment
  26. Case Reports – Fetus
  27. A case of diprosopus: a rare form of twinning radiology-pathology correlation
  28. Case Reports – Newborn
  29. Transmission of SARS-CoV-2 to premature twins from an asymptomatic mother
  30. Spinal dysraphism, club feet, and dextrocardia with situs inversus totalis in a neonate: a rare association and review
  31. Giant congenital vascular malformation: diagnostic approach and clinical course
  32. Transient neonatal myasthenia gravis following maternal myasthenia gravis presenting in pregnancy after treatment with Alemtuzumab
  33. Congenital pulmonary lymphangiectasia in an extremely low birth weight: a case report
  34. Congenital kaposiform hemangioendothelioma: don’t let the appearances fool you
  35. Agnathia-otocephaly complex: a case report and a literature review on recurrence risk
  36. Perinatal severe hypophosphatasia: a case report
  37. Recurrent neonatal group B streptococcus cellulitis and adenitis syndrome with late-onset sepsis
  38. Neonatal hypertension caused by left-to-right shunt flow through a patent ductus arteriosus in a premature infant
  39. Maternal Babesia infection associated with neonatal extramedullary hematopoiesis and acute myeloid leukemia in late infancy
  40. Congenital high airway obstruction syndrome complicated with foregut malformation and high airway fistula to the alimentary tract – a case series with four distinct types
  41. Aplasia cutis congenita as a consequence of fetal reduction in a triplet pregnancy
  42. Anhydramnios, but prenatally normal kidneys: renal tubular dysgenesis – patient with mutations in the renin-angiotensin system gene AGTR1
  43. Symptomatic and lethal congenital primary cardiac rhabdomyoma
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