Analog-Based Drug Discovery
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Analog-Based Drug Discovery
The Chemistry and Human Health Division Committee has reviewed the project proposal Analog-Based Drug Discovery and has approved the project as one of the divisional activities. The international team-work started in January 2003. The project is part of the work of the Subcommittee on Medicinal Chemistry and Drug Development.
Analogs of drugs play an important role in the evolution of drug discoveries. Statistically, every second drug is an analog, therefore, it is of interest to analyze the relationship of these drugs to the pioneer discoveries and to each other.
The goal of this project is publication of a reference book for medicinal chemists and students that provides an easily usable overview of drug-analogs and their role in medicinal chemistry.
The book will consist of the following chapters, to be written by the persons listed:
Introduction (Robin Ganellin)
Optimizing Drug Therapy by Analogs (Janos Fischer)
Analogs as Means of Discovering New Drugs (Camille G. Wermuth)
Drug Likeness and Analog-Based Drug Discovery (John Proudfoot)
Case Studies
Lacidipine (Giovanni Gaviraghi)
Pantoprazole (Jorg Senn-Bilfinger)
Esomeprazole (Per Lindberg)
Moxifloxacin (Uwe Petersen)
Azithromycin (Miljenko Dumic)
Drospirenone (Rudolf Wiechert)
Bisphosphonates (Eli Breuer)
Glucocorticoids (Zoltan Tuba)
Table of Drug-Analogs (Janos Fischer)
Subject Index
According to the schedule, the final manuscript will be ready by 30 June 2004. Proposals and further case studies are welcome.
For more information, contact the Task Group Chairman Janos Fischer<j.fischer@richter.hu>.
www.iupac.org/projects/2002/2002-051-1-700.html
Page last modified 17 March 2004.
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Articles in the same Issue
- Masthead
- From the Editor
- Contents
- Advancing the Business of IUPAC
- “The Times They Are A-Changing” and COCI Will Need to Sing Some New Songs
- One Step Further in IUPAC’s Campaign to Promote Sustainability and Chemistry
- Green Chemistry in Russia
- The Scientific Journey of Marini Bettolo from Italy to Uruguay
- Jens Christian Skou
- IUPAC Officers Meet with Chemistry Leaders in Kazan
- Post Genomic Chemistry
- Analog-Based Drug Discovery
- Glossary for Chemists of Terms Used in Toxicology–Revision and Updating
- Structure and Properties of Polymer/Clay Nano-Composite Materials
- Postgraduate Course in Polymer Science
- Functional Networks and Gels
- Macromolecule-Metal Complexes
- Mission and Challenges of Polymer Science and Technology
- IUPAC Solubility Data on the Internet
- Flow Analysis
- Organic Chemistry
- Interfaces and Interphases in Multicomponent Materials
- Molecular Characterization of Polymers: From Conventional Bulk Methods to Separation Procedures
- Medicinal Chemistry in Asia
- DNA Supramolecular Assemblies
- Biodegradable Polymers and Plastics
- Emulsion Polymerization and Latex Technology
- CHEMRAWN XV Chemistry for Water
- Coordination and Organometallic Chemistry
- Carbohydrates
- Organometallic Chemistry
- Chemical Thermodynamics
- Heteroatom Chemistry
- Mark Your Calendar
