Medicinal Chemistry in Drug Discovery, India
The increase in Medicinal Chemistry and Drug Discovery employment in Indian and Southeast Asian pharmaceutical companies and in the Contract Research Organizations collaborating with US and European companies has created a need for chemists and drug discovery scientists to acquire state-of-the-art knowledge of medicinal chemistry and other drug discovery areas. This course will emphasize the design strategy that takes into account drug metabolism and pharmacokinetics (DMPK), and toxicophore. The course will be based on the successful first year program in 2013 and the Drew University Residential School on Medicinal Chemistry, taught annually since 1986 on the Drew University campus in Madison, New Jersey. MCI 2015 will comprise 4.5 days of content, including 18-20 1-hour lectures on topics covering all aspects of medicinal chemistry from target selection and validatation, to hit identification, hit-to-lead chemistry, and lead optimization. New lectures on preclinical toxicity and clinical development will be added for the 2015 program. Four case history presentations of successful drug discovery programs will also be included. The course will be taught mainly by faculty from the US, with some local Indian faculty members also participating. The plan is to increase the number of Indian faculty members in subsequent years. The performance and value of the course will be assessed after the end of the three-year period, and a decision whether to continue in the same format made at that time. The desired outcome will be to enroll 80-100 attendees each year, and provide them with a strong introduction to the practice of medicinal chemistry in drug discovery. We are actively seeking the participation of other emerging or developing countries such as Singapore, Malaysia, South Africa, etc.
Following the success of the four-day Residential Course in Medicinal Chemistry (see Chem Int, March 2014, p.20), the current program is designed to educate drug discovery and early clinical development scientists from industry and academia, including the areas of medicinal chemistry, formulation chemistry, metabolism, and toxicology, on the importance of interplay among the different areas and their team efforts to execute a successful drug discovery and development process. The next Course is planned for February 2015.
For more information, contact the Task Group Chair Balu Balasubramanian <neel.balu@gmail.com>
©2014 by Walter de Gruyter Berlin/Boston
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Articles in the same Issue
- Masthead - Full issue pdf
- From the Editor
- Contents
- Features
- Planetary Boundaries and Chemical Pollution: A Grail Quest?
- Research Integrity: Science Community Needs to Address Threats by Research Assessments
- IUPAC and ICSU—A Comment
- Invitation to host the ICSU Secretariat for the Committee on Freedom and Responsibility in the conduct of Science (CFRS)
- Drug Design and Development: A Research Center More Than Twenty Years in the Making
- Youth Views on Sustainability: Size Matters, But So Does Speed
- IUPAC Wire
- Mort Hoffman Receives Chemistry Education Award
- Vânia G. Zuin is awarded the CHEMRAWN VII Prize for Atmospheric and Green Chemistry
- Sébastien Perrier received the 2014 IUPAC- Samsung Young Polymer Scientist Award
- DSM Materials Sciences Award 2014 goes to Prof. Jian Ping Gong
- 2015 IUPAC-SOLVAY International Award for Young Chemists announced
- In Memoriam: Gerrit den Boef
- The Project Place
- Critically evaluated rate parameters for chain-length-dependent termination in radical polymerization of styrene and n-alkyl methacrylates
- Guidelines for assigning values and calculating uncertainties to the standard atomic weights
- Nano-pesticides in the Environment
- Medicinal Chemistry in Drug Discovery, India
- Biological Context by TextData-mining
- IUPAC Recommendations for the definition, preferred symbol for all transport properties
- End-of-line hyphenation of systematic chemical names
- Making an imPACt
- Single-molecule fluorescence imaging by total internal reflection fluorescence microscopy (IUPAC Technical Report)
- Updates to the International System of Units (SI) brochure (8th edition)
- Variation in the terrestrial isotopic composition and atomic weight of argon (IUPAC Technical Report)
- Provisional Recommendations
- Nomenclature and Graphic Representations for Chemically Modified Polymers
- Conference Call
- Big Data for International Scientific Programmes
- CD3—A Celebration More Than 20 Years in the Making
- Solid State Chemistry
- Where 2B & Y
- Highlights in Medicinal Chemistry
- European Polymer Congress
- Point of Care Testing
- Research Integrity
- Mark Your Calendar
- Index 2014
- Stamps International
- The International Year of Crystallography (2014): A Philatelic Celebration
