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Medical textile implants: hybrid fibrous constructions towards improved performances

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Published/Copyright: March 12, 2024
Biomedical Engineering / Biomedizinische Technik
From the journal Biomedical Engineering / Biomedizinische Technik Volume 69 Issue 4

Abstract

Objectives

One main challenge for textile implants is to limit the foreign body reaction (FBR) and in particular the fibrosis development once the device is implanted. Fibrotic tissue in-growth depends on the fiber size, the pore size, and the organization of the fibrous construction. Basically, non-woven fibrous assemblies present a more favorable interface to biological tissues than do woven structures. However, they are mechanically less strong. In order to combine both strength and appropriate topography properties, the design of a hybrid fibrous construct was considered and discussed in this work.

Methods

Two polyethylene terephthalate (PET) weaves (satin and plain) were assembled with a non-woven PET mat, using an ultrasound welding process.

Results

The physical and mechanical properties of the construction as well as its ability to interact with the biological environment were then evaluated. In particular, the wettability of the obtained substrate as well as its ability to interact with mesenchymal stem cells (MSC) at 24 h (adhesion) and 72 h (proliferation) in vitro were studied.

Conclusions

The results show that the non-woven layer helps limiting cell proliferation in the plain weave construction and promotes conversely proliferation in the satin construction.

Keywords: hybrid textile valve; composite fabric design; hybrid textile; textile biomaterials; textile surface topography; foreign body reaction
Corresponding author: Foued Khoffi, Laboratoire de Génie Textile (LGTex), Ksar-Hellal, Tunisia, Phone: +216 73 450 999, E-mail:

  1. Research ethics: Not applicable.

  2. Informed consent: Not applicable.

  3. Author contributions: The authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  4. Competing interests: The authors state no conflict of interest.

  5. Research funding: None declared.

  6. Data availability: Not applicable.

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Received: 2023-07-22
Accepted: 2024-02-21
Published Online: 2024-03-12
Published in Print: 2024-08-27

© 2024 Walter de Gruyter GmbH, Berlin/Boston

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  5. Ergonomic RFID tag placement on surgical instruments – a preliminary user study
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https://doi.org/10.1515/bmt-2023-0335
Keywords for this article
hybrid textile valve; composite fabric design; hybrid textile; textile biomaterials; textile surface topography; foreign body reaction

Articles in the same Issue

  1. Frontmatter
  2. Review
  3. Actuators and transmission mechanisms in rehabilitation lower limb exoskeletons: a review
  4. Research Articles
  5. Ergonomic RFID tag placement on surgical instruments – a preliminary user study
  6. Medical textile implants: hybrid fibrous constructions towards improved performances
  7. Effect of calcium phosphate/bovine serum albumin coated Al2O3–Ti biocomposites on osteoblast response
  8. Self-supervised context-aware correlation filter for robust landmark tracking in liver ultrasound sequences
  9. Assessment of brain tumor detection techniques and recommendation of neural network
  10. A new approach for heart disease detection using Motif transform-based CWT’s time-frequency images with DenseNet deep transfer learning methods
  11. Structural EEG signal analysis for sleep apnea classification
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