Abstract
Measurement of features from the chaos theory or as popularly known, the concept of nonlinear dynamics, as indicatives of several pathological conditions and cognition states using the electroencephalography (EEG) signal is very popular. In this paper, the analysis of scalp EEG signals of normal subjects and brain tumour patients using the nonlinear dynamic features has been presented. The nonlinear dynamic features that represent the dimensional and waveform complexities of the signal being analyzed have been considered. The statistical analysis of the selected nonlinear dynamic features has been presented. The results show that the nonlinear dynamic features significantly discriminate the brain tumour group from the normal group.
Acknowledgment
Authors would like to express their gratitude to the Institute of Neurology at the Madras Medical College, Chennai, India for providing the data for the research work.
Research funding: None declared.
Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
Competing interests: Authors state no conflict of interest.
References
1. GBD 2016 Brain and Other CNS Cancer Collaborators. Global, regional, and national burden of brain and other CNS cancer, 1990-2016: a systematic analysis for the Global Burden of Disease Study. Lancet Neurol 2016;18:376–93.Search in Google Scholar
2. Forbes, LJL, Warburton, F, Richards, MA, Ramirez, AJ. Risk factors for delay in symptomatic presentation: a survey of cancer patients. Br J Cancer 2014;111:581–8.10.1038/bjc.2014.304Search in Google Scholar
3. American Brain Tumor Association (ABTA). About brain tumors - a primer for patients and caregivers; 2015. Available from: https://www.abta.org/wp-content/uploads/2018/03/about-brain-tumors-a-primer-1.pdf.Search in Google Scholar
4. Musella, A. Brain tumor symptoms survey results; 2010–2019. Available from: http://www.virtualtrials.com/braintumorsymptomssurvey.cfm.Search in Google Scholar
5. Husing, B, Jancke, L, Tag, B. Impact assessment of neuroimaging - Final Report. Amsterdam: IOS Press; 2006.10.3218/3151-5Search in Google Scholar
6. Walter, G. The location of cerebral tumors by electroencephalography. Lancet 1936;228:305–8.10.1016/S0140-6736(01)05173-XSearch in Google Scholar
7. Hartman, AM, Lesser, RP. Brain tumors and other space-occupying lesions. In: Niedermeyer, E, Lopes Da Silva, F, editors. Electroencephalography basic principles, clinical applications, and related fields. Philadelphia: Lippincott Williams & Wilkins; 2011:321–74 pp.Search in Google Scholar
8. Ko, DY. EEG in brain tumors; 2018. Available from: https://emedicine.medscape.com/article/1137982-overview#showall.Search in Google Scholar
9. Nagata, K, Gross, CE, Kindt, GW, Geier, MJ, Adey, GR. Topographic electroencephalographic study with power ratio index mapping in patients with malignant brain tumors. Neurosurgery 1985;17:613–9.10.1227/00006123-198510000-00014Search in Google Scholar PubMed
10. Silipo, R, Deco, G, Bartsch, H. Brain tumor classification based on EEG hidden dynamics. Intelligent Data Anal 1999;3:287–306.10.3233/IDA-1999-3404Search in Google Scholar
11. Habl, M, Bauer, Ch, Ziegaus, Ch, Lang, EW, Schulmeyer, F. Analyzing brain tumor related EEG signals with ICA algorithms. Artificial neural networks in medicine and biology. London: Springer; 2000:131–6 p.10.1007/978-1-4471-0513-8_18Search in Google Scholar
12. Karameh, FN, Dahleh, MA. Automated classification of EEG signals in brain tumor diagnostics. Proceedings of the 2000 American control conference. Piscataway, NJ: IEEE; 2000:4169–73 p.10.1109/ACC.2000.877006Search in Google Scholar
13. Chetty, S, Venayagamoorthy, GK. A neural network based detection of brain tumours using electroencephalography. Proceedings of IASTED international conference artificial intelligence and soft computing. Canada: ACTA Press; 2002:391–6 p.Search in Google Scholar
14. Boldyreva, GN, Sharova, EV, Koptelov, IuM., Shchepetkov, AN, Nikitin, KV, Kornienko, VN, et al.. Study of the genesis of pathological EEG patterns in tumor and traumatic lesions of the human brain. Hum Physiol 2005;31:18–25.10.1007/s10747-005-0003-6Search in Google Scholar
15. Murugesan, M, Sukanesh, R. Automated detection of brain tumor in EEG signals using artificial neural networks. In: Proceedings of 2009 international conference on advances in computing, control, and telecommunication technologies; 2009:284–8 pp.10.1109/ACT.2009.77Search in Google Scholar
16. Sharanreddy, M, Kulkarni, PK. Detection of primary brain tumor present in EEG signal using wavelet transform and neural network. Int J Biol Med Res 2013;4:2855–9.Search in Google Scholar
17. Stam, CJ. Nonlinear dynamical analysis of EEG and MEG: review of an emerging field. Clin Neurophysiol 2005;116:2266–301.10.1016/j.clinph.2005.06.011Search in Google Scholar PubMed
18. Rodriguez-Bermudez, G, Garcia-Laencina, PJ. Analysis of EEG signals using nonlinear dynamics and chaos: a review. Appl Math Inf Sci 2015;9:2309–21.Search in Google Scholar
19. Pritchard, WS, Duke, DW, Krieble, KK. Dimensional analysis of resting human EEG. II: surrogate-data testing indicates nonlinearity but not low-dimensional chaos. Psychophysiology 1995;32:486–91.10.1111/j.1469-8986.1995.tb02100.xSearch in Google Scholar
20. Babloyantz, A, Destexhe, A. Low-dimensional chaos in an instance of epilepsy. Proc Natl Acad Sci Neurobiol 1986;83:3513–7.10.1073/pnas.83.10.3513Search in Google Scholar
21. Jelles, B, van Birgelen, JH, Slaets, JPJ, Hekster, REM, Jonkman, EJ, Stam, CJ. Decrease of non-linear structure in the EEG of Alzheimer’s patients compared to healthy controls. Clin Neurophysiol 1999;110:1159–67.10.1016/S1388-2457(99)00013-9Search in Google Scholar
22. Heimans, JJ, Reijneveld, JC. Factors affecting the cerebral network in brain tumor patients. J Neuro Oncol 2012;108:231–7.10.1007/s11060-012-0814-7Search in Google Scholar PubMed PubMed Central
23. Picot, A, Charbonnier, S, Caplier, A. Monitoring drowsiness on-line using a single encephalographic channel. In: Barros de Mello, CA, editor. Biomedical Engineering. Croatia: In-Tech; 2009:145–64 pp.10.5772/7882Search in Google Scholar
24. Cacioppo, JT, Tassinary, LG, Berntson, GG. Handbook of psychophysiology. 3rd ed. Cambridge: Cambridge University Press; 2007.Search in Google Scholar
25. Lofhede, J. Classification of burst and suppression in the neonatal EEG. Thesis. Gothenburg, Sweden: Chalmers University of Technology; 2007.Search in Google Scholar
26. Gudmundsson, S, Runarsson, TP, Sigurdsson, S, Eiriksdottir, G, Johnsen, K. Reliability of quantitative EEG features. Clin Neurophysiol 2007;118:2162–71.10.1016/j.clinph.2007.06.018Search in Google Scholar PubMed
27. Ruiz, RAS, Ranta, R, Louis-Dorr, V. EEG montage analysis in the Blind Source Separation framework. Biomed Signal Process Control 2011;6:77–84.10.1016/j.bspc.2010.06.007Search in Google Scholar
28. D’Alessandro, M, Esteller, R, Vachtsevanos, G, Hinson, A, Echauz, J, Litt, B. Epileptic seizure prediction using hybrid feature selection over multiple intracranial EEG electrode contacts: a report of four patients. IEEE Trans Biomed Eng 2003;50:603–15.10.1109/TBME.2003.810706Search in Google Scholar
29. Esteller, R, Vachtsevanos, G, Echauz, J, Litt, B. A comparison of waveform fractal dimension algorithms. IEEE T Circuits-I 2001;48:177–83.10.1109/81.904882Search in Google Scholar
30. Sevcik, C. A procedure to estimate the fractal dimension of waveforms. Complexity Int 1998;5:1–18.Search in Google Scholar
31. Polychronaki, GE, Ktonas, PY, Gatzonis, S, Siatouni, A, Asvestas, PA, Tsekou, H, et al.. Comparison of fractal dimension estimation algorithms for epileptic seizure onset detection. J Neural Eng 2010;7:1–18.10.1109/BIBE.2008.4696822Search in Google Scholar
32. Abarbanel, HDI, Brown, R, Sidorowich, JJ, Tsimring, LS. The analysis of observed chaotic data in physical systems. Rev Modern Phys 1993;65:1331–92.10.1103/RevModPhys.65.1331Search in Google Scholar
33. Henriquez, P, Alonso, JB, Ferrer, MA, Travieso, CM, Godino-Llorente, JI, Diaz-de-Maria, F. Characterization of healthy and pathological voice through measures based on nonlinear dynamics. IEEE Transact Audio Speech Lang Process 2009;17:1186–95.10.1109/TASL.2009.2016734Search in Google Scholar
34. Henry, B, Lovell, N, Camacho, F. Nonlinear dynamics time series analysis. In: Akay, M, editor. Nonlinear biomedical signal processing volume II - dynamic analysis and modeling. New York: IEEE Press Series on Biomedical Engineering; 2001:1–39 pp.Search in Google Scholar
35. Lehnertz, K, Elger, CE. Can epileptic seizures be predicted? Evidence from nonlinear time series analysis of brain electrical activity. Phys Rev Lett 1998;80:5019–22.10.1103/PhysRevLett.80.5019Search in Google Scholar
36. Pincus, SM, Gladstone, IM, Ehrenkranz, RA. A regularity statistic for medical data analysis. J Clin Monitor 1991;7:335–45.10.1007/BF01619355Search in Google Scholar
37. Richman, JS, Moorman, JR. Physiological time-series analysis using approximate entropy and sample entropy. Am J Physiol Heart Circ Physiol 2000;278:H2039–49.10.1152/ajpheart.2000.278.6.H2039Search in Google Scholar
38. Bandt, C, Pompe, B. Permutation entropy: a natural complexity measure for time series. Phys Rev Lett 2002;88:1–4.10.1103/PhysRevLett.88.174102Search in Google Scholar
39. Chon, KH, Scully, CG, Lu, S. Approximate entropy for all signals. IEEE Eng Med Biol Mag 2009;28:18–23.10.1109/MEMB.2009.934629Search in Google Scholar
40. Riedl, M, Muller, A, Wessel, N. Practical considerations of permutation entropy: a tutorial review. Eur Phys J Spec Top 2013;222:249–62.10.1140/epjst/e2013-01862-7Search in Google Scholar
41. Breakspear, M, Terry, JR. Detection and description of non-linear interdependence in normal multichannel human EEG data. Clin Neurophysiol 2002;113:735–53.10.1016/S1388-2457(02)00051-2Search in Google Scholar
42. Pereda, E, Cruz, DM, Manas, S, Garrido, JM, Lopez, S, Gonzalez, JJ. Topography of EEG complexity in human neonates: effect of the postmenstrual age and the sleep state. Neurosci Lett 2006;394:152–7.10.1016/j.neulet.2005.10.036Search in Google Scholar PubMed
43. Jeong, J, Gore, JC, Peterson, BS. A method for determinism in short time series, and its application to stationary EEG. IEEE Trans Biomed Eng 2002;49:1374–9.10.1109/TBME.2002.804581Search in Google Scholar PubMed
44. Montgomery, DC, Runger, GC. Applied statistics and probability for Engineers. 3rd ed. New York: John Wiley & Sons; 2003.Search in Google Scholar
45. Krakovska, A, Stolc, S. Fractal complexity of EEG signal. Measurement Sci Rev 2006;6:63–6.Search in Google Scholar
© 2020 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Frontmatter
- Research Articles
- Nonlinear analysis of scalp EEGs from normal and brain tumour subjects
- Dimensionality reduction for EEG-based sleep stage detection: comparison of autoencoders, principal component analysis and factor analysis
- EEG signal classification based on SVM with improved squirrel search algorithm
- The effect of attentional focusing strategies on EMG-based classification
- Identification of dental pain sensation based on cardiorespiratory signals
- ScatT-LOOP: scattering tetrolet-LOOP descriptor and optimized NN for iris recognition at-a-distance
- A detailed and comparative work for retinal vessel segmentation based on the most effective heuristic approaches
- Visual enhancement of brain cancer MRI using multiscale dyadic filter and Hilbert transformation
- Raspberry Pi implemented with MATLAB simulation and communication of physiological signal-based fast chaff point (RPSC) generation algorithm for WBAN systems
- Short Communication
- How yarn orientation limits fibrotic tissue ingrowth in a woven polyester heart valve scaffold: a case report
Articles in the same Issue
- Frontmatter
- Research Articles
- Nonlinear analysis of scalp EEGs from normal and brain tumour subjects
- Dimensionality reduction for EEG-based sleep stage detection: comparison of autoencoders, principal component analysis and factor analysis
- EEG signal classification based on SVM with improved squirrel search algorithm
- The effect of attentional focusing strategies on EMG-based classification
- Identification of dental pain sensation based on cardiorespiratory signals
- ScatT-LOOP: scattering tetrolet-LOOP descriptor and optimized NN for iris recognition at-a-distance
- A detailed and comparative work for retinal vessel segmentation based on the most effective heuristic approaches
- Visual enhancement of brain cancer MRI using multiscale dyadic filter and Hilbert transformation
- Raspberry Pi implemented with MATLAB simulation and communication of physiological signal-based fast chaff point (RPSC) generation algorithm for WBAN systems
- Short Communication
- How yarn orientation limits fibrotic tissue ingrowth in a woven polyester heart valve scaffold: a case report