The emerging roles for histone demethylases in the modulation of signaling pathways

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Luisa Di Stefano
Luisa Di Stefano received her PhD in Life Science in 2004 at the European Institute of Oncology in Milan (Italy), where she identified and characterized novel members of the E2F family of transcription factors. As part of her postdoctoral work at the Massachusetts General Hospital Cancer Center and Harvard Medical School in Boston (USA), she studied the role of the histone demethylase dLsd1 in Drosophila. She is currently a group leader at the LBCMCP, Université Paul Sabatier in Toulouse (France). Her research focuses on the identification of novel dLsd1 partners important for development and tumorigenesis.
and Nicholas J. Dyson
Nicholas J. Dyson, PhD, has been a faculty member at the Massachusetts General Hospital Cancer Center and Harvard Medical School (Boston, USA) for over 20 years. His research focuses on the RB tumor suppressor and related proteins. His accomplishments include the discovery that pRB is targeted by human papillomavirus E7 proteins, the finding that pRB and p107/p130 are required for the regulation of different sets of E2F-target genes, and the identification and analysis of Drosophila E2F, DP and RB family members. Dr. Dyson is currently the Scientific Director of the MGH Cancer Center.