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Pleural fluid/serum immunoglobulin ratio is a diagnostic marker for congenital chylothorax in utero

  • Kiyomi Tsukimori , Naoyuki Nakanami , Kotaro Fukushima , Takazumi Yoshimura , Shunji Hikino and Hitoo Nakano
Published/Copyright: July 19, 2006
Journal of Perinatal Medicine
From the journal Volume 34 Issue 4

Abstract

Objective: To distinguish congenital chylothorax from other causes of hydrothorax in utero.

Methods: Serum and pleural fluid samples from 8 fetuses with congenital chylothorax and 5 control fetuses with other causes of hydrothorax were tested for total protein, albumin, IgG, IgA, and IgM.

Results: Fetuses with congenital chylothorax had higher levels of IgG in pleural fluid, but not the other four proteins, than control fetuses (P<0.05). There were no significant differences in serum proteins among fetuses. When we examined pleural fluid to serum ratios, the IgG ratio in fetuses with congenital chylothorax was significantly higher than that of control fetuses (P<0.05). The IgG ratio in chylothorax was greater than 0.6 regardless of lymphocyte count.

Conclusion: Pleural fluid/serum IgG ratio may be a diagnostic marker for congenital chylothorax in utero.

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Corresponding author: Kiyomi Tsukimori MD, PhD Department of Obstetrics and Gynecology Graduate School of Medical Sciences, Kyushu University Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan Tel.: +81-92-642-5395, Fax: +81-92-642-5414,

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Published Online: 2006-07-19
Published in Print: 2006-08-01

©2006 by Walter de Gruyter Berlin New York

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  9. Maturation of the autonomic nervous system: differences in heart rate variability in premature vs. term infants
  10. Four chamber view plus three-vessel and trachea view for a complete evaluation of the fetal heart during the second trimester
  11. Pleural fluid/serum immunoglobulin ratio is a diagnostic marker for congenital chylothorax in utero
  12. Fetal brain sparing is strongly related to the degree of increased placental vascular impedance
  13. Outcome of fetuses in women with pregestational diabetes mellitus
  14. Outcome of fetuses in women with pregestational diabetes mellitus
  15. Inhaled nitric oxide therapy might reduce the need for hyperventilation therapy in infants with persistent pulmonary hypertension of the newborn
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  17. Infective puerperal endocarditis caused by Escherichia coli
  18. Correlation between plasma and urinary caffeine levels in preterm infants
  19. Fetal ascites secondary to urinary hydrocolpos
  20. Congress Calendar
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