In-line filters in central venous catheters in a neonatal intensive care unit
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Agnes van den Hoogen
, Tannette G. Krediet , Cuno S.P.M. Uiterwaal , Jeroen F.G.A. Bolenius , Leo J. Gerards and André Fleer
Abstract
Nosocomial sepsis remains an important cause of morbidity in neonatal intensive care units. Central venous catheters (CVCs) and parenteral nutrition (TPN) are major risk factors. In-line filters in the intravenous (IV) administration sets prevent the infusion of particles, which may reduce infectious complications. We randomized infants to in-line filter (for clear fluids and lipid emulsions) or no filter placement. Sepsis, nursing time and costs were assessed. IV sets without filters were changed every 24 h, IV-sets with filters every 96 h. Of 442 infants with a CVC, 228 were randomized to filter placement, 214 to no filter. No differences were found in clinical characteristics, CVC-use, and catheter days. Nosocomial sepsis occurred in 37 (16.2%) infants with filters, in 35 (16.3%) in the group without filter (NS). Nursing time to change the IV-administration sets was 4 min shorter in the filter-group (P<0.05). Costs of materials used were comparable.
In conclusion, the incidence of sepsis when using filters was not reduced but the nursing time for changing the intravenous sets was reduced without a difference in costs.
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©2006 by Walter de Gruyter Berlin New York
Articles in the same Issue
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Articles in the same Issue
- WAPM-Newsletter No 1/2006 7thWORLD CONGRESS OF PERINATAL MEDICINE in Zagreb, September 21–24, 2005
- Cerebral palsy and fetal inflammatory response syndrome: a review
- A sonographic short cervix as the only clinical manifestation of intra-amniotic infection
- Suppression of IL-2 and IFN-γ production in women with spontaneous preterm labor
- Does practice make perfect? An age-matched study on grand multiparity in Flanders, Belgium
- Efficacy of a strategy to prevent neonatal early-onset group B streptococcal (GBS) sepsis
- Four-dimensional ultrasonography of the fetal heart using a novel Tomographic Ultrasound Imaging display
- Normal standards for fetal neurobehavioral developments – longitudinal quantification by four-dimensional sonography
- Selective surfactant prophylaxis in preterm infants born at ≤31 weeks' gestation using the stable microbubble test in gastric aspirates
- In-line filters in central venous catheters in a neonatal intensive care unit
- Integrating the role of infection in prediction and prevention of preterm delivery
- Studies on the prevalence of human papillomavirus in pregnant women in Japan
- Unilateral pulmonary agenesis
- Posterior reversible leucoencephalopathy syndrome: a rare complication of preeclampsia
- Isolated spontaneous fetal heart rate decelerations: prognostic significance
- Combination of vasa praevia, true umbilical cord knot and a subserosal hemorrhage
- Neonatal pneumopericardium
- Congress Calendar
- Roster of Perinatal Societies