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Pregnancy complicated with pure red cell aplasia: a case report

  • Y. Makino , M. Nagano , K. Tamura and T. Kawarabayashi
Published/Copyright: June 1, 2005
Journal of Perinatal Medicine
From the journal Volume 31 Issue 6

Abstract

A 31-year-old Japanese pregnant woman had no remarkable previous medical and family histories except for artificial abortion in 1993. A full-term normal infant was subsequently delivered in 1998. In this pregnancy, she began to experience general fatigability with a hemoglobin concentration of 8.5 g/dl at 19 weeks of gestation. Although she had been treated with intravenous iron, the hemoglobin decreased to 6.0 g/dl. She was referred to our hospital at 34 weeks of gestation. The laboratory data were as follows on this admission; hemoglobin 5.1 g/dl, RBC 128 × 104/l, reticulocytes 1.1%, WBC 7.1 × 109/l, platelet count 229 × 109/l, folic acid 5.6 ng/ml, serum vitamin B12 200 pg/ml, ferritin 184 ng/ml, parvovirus B19 (−). A bone marrow aspiration revealed normal granulopoiesis and megakaryocytes, but almost complete absence of erythropoietic precursors. A diagnosis of pure red cell aplasia was made due to these findings.

Treatment with prednisone (50 mg/day) and blood transfusion was started before delivery. She was delivered transvaginally at 37 weeks of gestation. The neonate was a normal female infant without anemia (hemoglobin 17.9 g/dl) and the 1 minute Apgar score was 8. Her hemoglobin level rose to 12.1 g/dl spontaneously two weeks after delivery.

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Published Online: 2005-06-01
Published in Print: 2003-11-20

Copyright © 2003 by Walter de Gruyter GmbH & Co. KG

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