Stable microbubble test and click test to predict respiratory distress syndrome in preterm infants not requiring ventilation at birth
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H. H. Fiori
Abstract
Aims: To determine the usefulness of the stable microbubble test (SMT) and of the click test (CT) on gastric aspirates obtained soon after birth to predict respiratory distress syndrome (RDS) in preterm babies not requiring ventilation at birth.
Patients and methods: The study was carried out with a cohort between 24 and 34 weeks of gestational age. Gastric secretions were collected before 1 hour of life and frozen for further analysis.
Results: 110 neonates were studied. For a cut-off value ≤ 10 microbubbles/mm2 (mb/mm2) the sensitivity and specificity to predict RDS were 73.9% and 92%, respectively, in the SMT. The best SMT cut-off point to predict RDS was ≤ 15 mb/mm2 (sensitivity = 82.6%;specificity = 85.1%) if equal weight was given to false-positive and false-negative results. CT (104 samples) showed a sensitivity of 100% and a specificity of 45.1% to predict RDS. The overall accuracy of the SMT was better than the overall accuracy of the CT (87.5% vs. 64.4%; p < 0.001) to predict RDS.
Conclusions: The SMT is more accurate than the CT to predict RDS in infants below 35 weeks of gestational age and may be helpful to select patients to receive surfactant.
Copyright © 2003 by Walter de Gruyter GmbH & Co. KG
Articles in the same Issue
- Author Index
- Subject Index
- Contents
- MRI during pregnancy
- Magnetic resonance imaging and ultrasound in the assessment of the fetal central nervous system
- Maternal erythrocyte malondialdehyde level in preeclampsia prediction: a longitudinal study
- Effect of fetal macrosomia on human placental glucose transport and utilization in insulin-treated gestational diabetes
- Association between maternal-fetal Doppler velocimetry and fetal lung maturity
- Does the thrifty phenotype result from chronic glutamate intoxication? A hypothesis
- Fetal hand movements and facial expression in normal pregnancy studied by four-dimensional sonography
- Stable microbubble test and click test to predict respiratory distress syndrome in preterm infants not requiring ventilation at birth
- Staphylococcal scalded skin syndrome in two very low birth weight infants
- Umbilical glutathione levels are higher after vaginal birth than after cesarean section
- Gastrointestinal contrast studies in high-risk neonates with suspected necrotising enterocolitis – a note of caution
- Fatal intracranial hemorrhage in a pregnant patient with autoimmune thrombocytopenic purpura
- Pregnancy complicated with pure red cell aplasia: a case report
- Mucopolysaccharidosis type VII as a cause of recurrent non-immune hydrops fetalis
- Higher risk of persistent pulmonary hypertension of the newborn after cesarean
- Congress Calendar
Articles in the same Issue
- Author Index
- Subject Index
- Contents
- MRI during pregnancy
- Magnetic resonance imaging and ultrasound in the assessment of the fetal central nervous system
- Maternal erythrocyte malondialdehyde level in preeclampsia prediction: a longitudinal study
- Effect of fetal macrosomia on human placental glucose transport and utilization in insulin-treated gestational diabetes
- Association between maternal-fetal Doppler velocimetry and fetal lung maturity
- Does the thrifty phenotype result from chronic glutamate intoxication? A hypothesis
- Fetal hand movements and facial expression in normal pregnancy studied by four-dimensional sonography
- Stable microbubble test and click test to predict respiratory distress syndrome in preterm infants not requiring ventilation at birth
- Staphylococcal scalded skin syndrome in two very low birth weight infants
- Umbilical glutathione levels are higher after vaginal birth than after cesarean section
- Gastrointestinal contrast studies in high-risk neonates with suspected necrotising enterocolitis – a note of caution
- Fatal intracranial hemorrhage in a pregnant patient with autoimmune thrombocytopenic purpura
- Pregnancy complicated with pure red cell aplasia: a case report
- Mucopolysaccharidosis type VII as a cause of recurrent non-immune hydrops fetalis
- Higher risk of persistent pulmonary hypertension of the newborn after cesarean
- Congress Calendar
