Association between maternal-fetal Doppler velocimetry and fetal lung maturity
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J. J. Piazze
Abstract
Aims: To correlate maternal-fetal Doppler velocimetry parameters to indices of fetal lung maturity (FLM).
Methods: Fifty-five consecutive third trimester pregnancies in which a pulsed-wave Doppler study, including uterine resistance index (Ut RI), umbilical artery pulsatility index (UA PI), middle cerebral artery pulsatility index (MCA PI) and the UA/MCA ratio was performed within 24 hours before amniocentesis and within a week from birth. FLM was determined by amniotic fluid lamellar bodies count (LBs).
Results: A positive correlation between MCA PI and LBs (p < 0.007, r = 0.44) was found. MCA PI showed a trend to lower values in fetuses that developed RDS at birth (1.3±0.5 vs. 1.7±0.4, NS). LBs significantly decreased as Ut RI increased (O.R.: 0.98, C.I. 0.97–0.99, p < 0.05). A mean Ut RI > 0.64 was correlated to delayed FLM (LBs < 20,000/μl; sensitivity: 90.9%, specificity: 90.3%; positive predictive value: 76.9%, negative predictive value: 96.6%).
Comment: In third trimester pregnancies abnormal uterine artery waveforms may be associated to a delayed FLM, as expressed by decreased amniotic fluid LBs.
Copyright © 2003 by Walter de Gruyter GmbH & Co. KG
Articles in the same Issue
- Author Index
- Subject Index
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- Maternal erythrocyte malondialdehyde level in preeclampsia prediction: a longitudinal study
- Effect of fetal macrosomia on human placental glucose transport and utilization in insulin-treated gestational diabetes
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- Fatal intracranial hemorrhage in a pregnant patient with autoimmune thrombocytopenic purpura
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- Mucopolysaccharidosis type VII as a cause of recurrent non-immune hydrops fetalis
- Higher risk of persistent pulmonary hypertension of the newborn after cesarean
- Congress Calendar
Articles in the same Issue
- Author Index
- Subject Index
- Contents
- MRI during pregnancy
- Magnetic resonance imaging and ultrasound in the assessment of the fetal central nervous system
- Maternal erythrocyte malondialdehyde level in preeclampsia prediction: a longitudinal study
- Effect of fetal macrosomia on human placental glucose transport and utilization in insulin-treated gestational diabetes
- Association between maternal-fetal Doppler velocimetry and fetal lung maturity
- Does the thrifty phenotype result from chronic glutamate intoxication? A hypothesis
- Fetal hand movements and facial expression in normal pregnancy studied by four-dimensional sonography
- Stable microbubble test and click test to predict respiratory distress syndrome in preterm infants not requiring ventilation at birth
- Staphylococcal scalded skin syndrome in two very low birth weight infants
- Umbilical glutathione levels are higher after vaginal birth than after cesarean section
- Gastrointestinal contrast studies in high-risk neonates with suspected necrotising enterocolitis – a note of caution
- Fatal intracranial hemorrhage in a pregnant patient with autoimmune thrombocytopenic purpura
- Pregnancy complicated with pure red cell aplasia: a case report
- Mucopolysaccharidosis type VII as a cause of recurrent non-immune hydrops fetalis
- Higher risk of persistent pulmonary hypertension of the newborn after cesarean
- Congress Calendar
