Plasma adrenomedullin levels in pregnancies with appropriate for gestational age and small for gestational age infants
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C. Yamashiro
Abstract
Aims: To evaluate whether maternal and fetal plasma adrenomedullin levels in pregnancies with small for gestational age (SGA) infants are different from those in pregnancies with appropriate for gestational age (AGA) infants. Methods: Maternal and fetal circulating adrenomedullin levels were compared between 62 pregnancies with AGA (43 delivered vaginally and 19 delivered by elective cesarean section) and 28 pregnancies with SGA (20 delivered vaginally and 8 delivered by elective cesarean section) at birth. Plasma adrenomedullin levels were measured from maternal and cord venous blood samples using a radioimmunoassay. Umbilical artery blood pH was also measured. Results: There were no significant differences for maternal total adrenomedullin levels, mature adrenomedullin levels, and its ratio among the groups. There were also no significant differences for fetal total adrenomedullin levels, mature adrenomedullin levels, and its ratio among the groups. In the AGA group delivered vaginally, fetal mature/total adrenomedullin ratio (mean ± standard error, 16.6 ± 0.7%) was significantly higher than the maternal ratio (13.8 ± 0.6%) (p < 0.05). In the SGA group delivered vaginally, fetal mature/total adrenomedullin ratio (18.5 ± 1.0%) was also significantly higher than the maternal ratio (14.5 ± 0.6%) (p < 0.05). There was no significant difference in umbilical artery blood pH among the groups. Conclusions. These results suggest that maternal and fetal plasma circulating adrenomedullin levels may play a role in maternal and fetal cardiovascular adaptation during delivery in pregnancies with both AGA and SGA infants.
Copyright © 2001 by Walter de Gruyter GmbH & Co. KG
Articles in the same Issue
- Author Index
- Subject Index
- Contents
- Fetal and maternal energy metabolism during labor in relation to the available caloric substrate
- Incidence of meconium aspiration syndrome in term meconium-stained babies managed at birth with selective tracheal intubation
- Predicting preterm delivery and lowering very preterm delivery rate
- Comparative effects of chronic exposure to glucose or sodium butyrate on surfactant development in fetal rabbits
- Eigenvector based spatial filtering of fetal biomagnetic signals
- Localization and quantification of adhesion molecule expression in the lower uterine segment during premature labor
- Is intrapartum vibroacoustic stimulation an effective predictor of fetal acidosis?
- Plasma adrenomedullin levels in pregnancies with appropriate for gestational age and small for gestational age infants
- Tissue concentrations of cytokines in the lower uterine segment during preterm parturition
- Effect of labor on maternal dehydration, starvation, coagulation, and fibrinolysis
- Changes in light-induced fluorescence of cervical collagen in guinea pigs during gestation and after sodium nitroprusside treatment
- Cardiotocography or Doppler in making delivery decision?
- Book review
- Congress Calendar
Articles in the same Issue
- Author Index
- Subject Index
- Contents
- Fetal and maternal energy metabolism during labor in relation to the available caloric substrate
- Incidence of meconium aspiration syndrome in term meconium-stained babies managed at birth with selective tracheal intubation
- Predicting preterm delivery and lowering very preterm delivery rate
- Comparative effects of chronic exposure to glucose or sodium butyrate on surfactant development in fetal rabbits
- Eigenvector based spatial filtering of fetal biomagnetic signals
- Localization and quantification of adhesion molecule expression in the lower uterine segment during premature labor
- Is intrapartum vibroacoustic stimulation an effective predictor of fetal acidosis?
- Plasma adrenomedullin levels in pregnancies with appropriate for gestational age and small for gestational age infants
- Tissue concentrations of cytokines in the lower uterine segment during preterm parturition
- Effect of labor on maternal dehydration, starvation, coagulation, and fibrinolysis
- Changes in light-induced fluorescence of cervical collagen in guinea pigs during gestation and after sodium nitroprusside treatment
- Cardiotocography or Doppler in making delivery decision?
- Book review
- Congress Calendar
