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Effect of high amniotic fluid pressure on fetal circulation

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Published/Copyright: June 1, 2005
Journal of Perinatal Medicine
From the journal Volume 28 Issue 3

Abstract

The purpose of this study was to investigate the effects of high amniotic fluid pressure (AFP) created by amnioinfusion on fetal circulation. Five pregnant goats whose fetuses had a mean gestational age of 131 ± 2 days (term 145 days) were used. After a 30 minute control period, 1500 ml of warm saline was infused to the amniotic cavity over a period of 30 minutes. The AFP gradually increased during amnioinfusion and remained 2–3 mmHg above the control level for 3 hours after amnioinfusion. Fetal arterial pH (FpH) tended to decrease, and there was a significant negative correlation between the FpH and AFP (r= −0.723). Fetal arterial pO2 also tended to decrease and negatively correlated to the AFP (r= −0.59). On the other hand, fetal arterial pCO2 tended to increase and positively correlated with the AFP (r = 0.75). Although amnioinfusion is useful for improving the status of a distressed fetus, the fetal condition may be jeopardized at the same time. Therefore, careful monitoring of the AFP and fetal status is recommended during amnioinfusion.

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Published Online: 2005-06-01
Published in Print: 2000-07-04

Copyright (c)2000 by Walter de Gruyter GmbH & Co. KG

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