Prenatal and perinatal risk factors for autism
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Larry Burd
Abstract
Aim: To identify pre- and perinatal risk factors for autism.
Method: Case control study. We matched names of patients from North Dakota who met DSM criteria for autism, a pervasive developmental disorder, and autisticdisorder with their birth certificates. Five matched controls were selected for each case.
Results: Univariate analysis of the 78 cases and 390 controls identified seven risk factors. Logistic modeling to control for confounding produced a five variable model. The model parameters were χ2 = 36.6 and p <0.001. The five variables in the model were decreased birth weight, low maternal education, later start of prenatal care, and having a previous termination of pregnancy. Increasing father's age was associated with increased risk of autism.
Conclusion: This methodology may provide an inexpensive method for clinics and public health providers to identify risk factors and to identify maternal characteristics of patients with mental illness and developmental disorders.
Copyright (c)1999 by Walter de Gruyter GmbH & Co. KG
Articles in the same Issue
- Contents
- Author Index
- Subject Index
- Birth of St. Mary (St. Anne’s parturition) in the light of messages from medical education: Three examples from Croatian sacral heritage
- Are color and pulsed Doppler sonography safe in early pregnancy?
- European Community Multi-Center Trial “Fetal ECG Analysis During Labor”: ST plus CTG analysis
- Prenatal and perinatal risk factors for autism
- Rupture of membranes before 26 weeks of gestation: Outcome of 148 consecutive cases
- Coagulation and fibrinolysis in viable mid-trimester pregnancies of normal, intrauterine growth retardation, chromosomal anomalies and hydrops fetalis and their eventual obstetric outcome
- Determinants of energy expenditure in ventilated preterm infants
- Perinatal outcome and management of single fetal death in twin pregnancy: A case series and review
- Comparison between creatine kinase brain isoenzyme (CKBB) activity and Sarnat score for prediction of adverse outcome following perinatal asphyxia
- Neonatal outcome in small for gestational age infants: Do they really better?
- Chronic lung disease and survival in 4 tertiary neonatal units
- Follow-up studies of newborn-babies with congenital ventriculomegaly
Articles in the same Issue
- Contents
- Author Index
- Subject Index
- Birth of St. Mary (St. Anne’s parturition) in the light of messages from medical education: Three examples from Croatian sacral heritage
- Are color and pulsed Doppler sonography safe in early pregnancy?
- European Community Multi-Center Trial “Fetal ECG Analysis During Labor”: ST plus CTG analysis
- Prenatal and perinatal risk factors for autism
- Rupture of membranes before 26 weeks of gestation: Outcome of 148 consecutive cases
- Coagulation and fibrinolysis in viable mid-trimester pregnancies of normal, intrauterine growth retardation, chromosomal anomalies and hydrops fetalis and their eventual obstetric outcome
- Determinants of energy expenditure in ventilated preterm infants
- Perinatal outcome and management of single fetal death in twin pregnancy: A case series and review
- Comparison between creatine kinase brain isoenzyme (CKBB) activity and Sarnat score for prediction of adverse outcome following perinatal asphyxia
- Neonatal outcome in small for gestational age infants: Do they really better?
- Chronic lung disease and survival in 4 tertiary neonatal units
- Follow-up studies of newborn-babies with congenital ventriculomegaly
