Pulmonary hemorrhage in neonates of early and late gestation
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Vineet Bhandari
Abstract
Our objectives in this study of pulmonary hemorrhage (PH) were to define common characteristics of infants who develop PH, identify factors associated with PH and report the outcome. Neonates (42/2980 admissions) with PH and matched controls were identified. Early gestation ≤35 weeks) infants with PH [EGPH] (n = 34; 12 survived) had occurrence of PH at 3.6 ± 1.1 (mean ± sem) days and were significantly associated with multiple births (p = 0.03), RDS (p < 0.01) and use of Survanta (p < 0.02). Among EGPH, small for gestational age (SGA) infants (n = 7) had a 100% mortality rate. Late gestation (≥ 36 weeks) infants with PH [LGPH] (n = 8; 6 survived) had occurrence of PH at 0.7 ± 0.3 days and were significantly associated with low 1 minute (p = 0.04) and 5 minutes (p = 0.01) Apgar scores. All infants were managed with increases in mean airway pressure (MAP) and/or use of cocaine/epinephrine through the endotracheal tube. We have identified 2 groups of neonates with distinct factors associated with PH; use of 1:10,000 epinephrine (0.1 ml/kg) and/or 4% cocaine (4 mg/kg) may be useful adjuncts to increases in MAP for management of PH.
Copyright (c)1999 by Walter de Gruyter GmbH & Co. KG
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Articles in the same Issue
- Cord occlusion techniques for selective termination in monochorionic twins
- Comparison of vaginal and cesarean section delivery for fetuses in breech presentation
- Neonatal cerebral Doppler: Arterial and venous flow velocity measurements using color and pulsed Doppler system
- MMP/TIMP imbalance in amniotic fluid during PROM: an indirect support for endogenous pathway to membrane rupture
- Pulmonary hemorrhage in neonates of early and late gestation
- Nucleated red blood cells in cord blood of singleton term and post-term neonates
- Neonatal lung function in very immature infants with and without RDS
- Doppler sonographic findings for hypertension in pregnancy and HELLP syndrome
- Vitamin E status of infants at birth
- Successful transcutaneous arterial embolization of a giant hemangioma associated with high-output cardiac failure and Kasabach-Merritt syndrome in a neonate: A case report
- 1H NMR as a non-invasive probe of amniotic fluid in insulin dependant diabetes mellitus
