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Congestive heart failure as an initial manifestation of reninoma
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Min Jung Cho
Published/Copyright:
November 1, 2011
Abstract
Reninoma or juxtaglomerular cell tumor (JCT) of the kidney is a rare but curable cause of severe hypertension. We report a case of reninoma in an 18-year-old woman. Interestingly, she initially presented with dilated cardiomyopathy, without any relevant history or signs of hypertension. Malignant hypertension, one of the cardinal signs of JCT, did not become apparent in the patient until several months later. Following a thorough evaluation, we detected a small mass in the left renal cortex as well as elevated plasma renin activity, which suggested the presence of a renin-producing tumor in the kidney. The patient’s blood pressure and plasma renin activity rapidly declined after a successful laparoscopic partial nephrectomy. We postulate that hyperreninemic-hyperaldosteronism followed by fluid retention caused a sudden severe increase in ventricular afterload and subsequent congestive heart failure in this patient.
Received: 2011-6-7
Accepted: 2011-9-3
Published Online: 2011-11-01
Published in Print: 2011-12-01
©2011 by Walter de Gruyter Berlin Boston
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Keywords for this article
aldosterone;
cardiac failure;
hypertension;
juxtaglomerular cell tumor;
renin
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