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Serum sickness-like syndrome after immunoglobulin M-enriched polyclonal immunoglobulin

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Published/Copyright: November 22, 2010
Drug Metabolism and Personalized Therapy
From the journal Volume 25 Issue 1-4

Abstract

Medication reactions, infectious etiologies, graft vs. host disease, serum sickness, and serum sickness-like reaction are the most common conditions that cause skin fever and rashes in immunosuppressed patients. In addition to this long list of diseases, severity of the primary disease and deterioration in the patient’s health status can make the diagnosis difficult. Furthermore, cutaneous and histological similarities in these mentioned conditions can be confounding. Here, we present a 16-year-old male patient with acute myeloid leukemia suffering from skin rashes and fever that appeared following a chemotherapy course leading to bone marrow suppression. We aim to discuss the differential diagnosis and share the diagnostic challenges that we already have experienced after immunoglobulin M-enriched polyclonal immunoglobulin.

Keywords: immunoglobulin M-enriched polyclonal immunoglobulin; immunosuppressed; serum sickness; serum sickness-like reaction
Corresponding author: Fatih Mehmet Azik, Department of Pediatric Hematology, Ankara Children’s Hematology Oncology Hospital, Diskapı, 06110 Ankara, Turkey Phone: +90-312-3172669, Fax: +90-312-3187363
Published Online: 2010-11-22
Published in Print: 2010-12-01

©2010 by Walter de Gruyter Berlin New York

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  4. Reviews
  5. P-Glycoprotein- and cytochrome P-450-mediated herbal drug interactions
  6. Effect of metal ions on some pharmacologically relevant interactions involving fluoroquinolone antibiotics
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  9. Preemptive dose reduction of warfarin in patients initiating metronidazole
  10. Short Communication
  11. Linezolid interaction with serotonin reuptake inhibitors: report of two cases and incidence assessment
  12. Case Report
  13. Serum sickness-like syndrome after immunoglobulin M-enriched polyclonal immunoglobulin
https://doi.org/10.1515/DMDI.2010.005
Keywords for this article
immunoglobulin M-enriched polyclonal immunoglobulin; immunosuppressed; serum sickness; serum sickness-like reaction

Articles in the same Issue

  1. Publisher's Note
  2. Publisher's Note
  3. Publisher's Note
  4. Reviews
  5. P-Glycoprotein- and cytochrome P-450-mediated herbal drug interactions
  6. Effect of metal ions on some pharmacologically relevant interactions involving fluoroquinolone antibiotics
  7. Original Articles
  8. Prediction of drug clearance in children 3 months and younger: an allometric approach
  9. Preemptive dose reduction of warfarin in patients initiating metronidazole
  10. Short Communication
  11. Linezolid interaction with serotonin reuptake inhibitors: report of two cases and incidence assessment
  12. Case Report
  13. Serum sickness-like syndrome after immunoglobulin M-enriched polyclonal immunoglobulin
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