Butyrylcholinesterase activity and metabolic syndrome in obese patients
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Vânia M. Alcântara
Abstract
Total butyrylcholinesterase activity (EC 3.1.1.8) was previously suggested as a marker for metabolic syndrome. The present study examined total butyrylcholinesterase activity and the relative and absolute activities of two butyrylcholinesterase electrophoretic bands (C 4/5 and C OF) in 99 obese individuals (body mass index ≥30kg/m 2) presenting the CHE2 C5 − phenotype of the CHE2 gene. Anthropometric, hormonal and biochemical variables already associated with metabolic syndrome were also examined. The data from these obese individuals of the CHE2 C5− phenotype show that total butyrylcholinesterase activity and the absolute activities of the C 4/5 and C OF electrophoretic bands are associated with metabolic syndrome and with variables related to it. These butyrylcholinesterase activities do not behave as independent risk factors for metabolic syndrome, but can be considered as secondary markers for this syndrome in obese individuals with the CHE2 C5− phenotype.
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©2005 by Walter de Gruyter Berlin New York
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Articles in the same Issue
- Effect of stress doses of hydrocortisone on S-100B vs. interleukin-8 and polymorphonuclear elastase levels in human septic shock
- Conjugated linoleic acid suppresses the secretion of atherogenic lipoproteins from human HepG2 liver cells
- Determination of debrisoquine and 4-hydroxydebrisoquine by high-performance liquid chromatography: application to the evaluation of CYP2D6 genotype and debrisoquine metabolic ratio relationship
- Assessment of iodine intake in mildly iodine-deficient pregnant women by a new automated kinetic urinary iodine determination method
- Butyrylcholinesterase activity and metabolic syndrome in obese patients
- The non-thyroidal illness syndrome after coronary artery bypass grafting: a 6-month follow-up study
- Advanced oxidation protein products (AOPP) for monitoring oxidative stress in critically ill patients: a simple, fast and inexpensive automated technique
- Quality control in urinary stone analysis: results of 44 ring trials (1980–2001)
- External Quality Assessment in The Netherlands: time to introduce commutable survey specimens. Lessons from the Dutch “Calibration 2000” project
- Evaluation of a high-sensitivity turbidimetric immunoassay for serum C-reactive protein: application to the study of longitudinal changes throughout normal pregnancy
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- Preanalytical variability in laboratory testing: influence of the blood drawing technique
- Soluble transferrin receptor and transferrin receptor-ferritin index in iron deficiency anemia and anemia in rheumatoid arthritis
- Elevated plasma cysteinylglycine levels caused by cilastatin-associated antibiotic treatment
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- Reply to W.G. Wood. Questionable results – who directs the EQAS organisers? Clin Chem Lab Med 2004;42:1073
- The predictive power of serum κ/λ ratios for discrimination between monoclonal gammopathy of undetermined significance and multiple myeloma
- 4th Conference on Hyperhomocysteinemia: Saarbrücken, Germany, April, 14–16, 2005, Saarland University
