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Reference regions of two or more dimensions
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James C. Boyd
Published/Copyright:
June 1, 2005
Abstract
Despite being proposed over 30 years ago, the multivariate reference region (MRR) remains an interpretive tool with uncertain value in clinical practice. This paper reviews the mathematical theory of the MRR, presents topics in the clinical application of MRRs, and examines the advantages and disadvantages of MRRs. Finally, some thoughts are offered regarding future directions for work in this field.
Published Online: 2005-6-1
Published in Print: 2004-7-5
Copyright © 2004 by Walter de Gruyter GmbH & Co. KG
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- Reference values: from philosophy to a tool for laboratory medicine
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- Selecting clinically relevant populations for reference intervals
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- Proposal for guidelines to establish common biological reference intervals in large geographical areas for biochemical quantities measured frequently in serum and plasma
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