Arterial Tissue of Arsenic, Selenium and Iron in Blackfoot Disease Patients
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Chin Thin Wang
Abstract
In order to identify arsenic as one of the major factors that cause Blackfoot disease on the southwest coast of Taiwan, an atomic absorption spectrophotometric method was used to determine arsenic, selenium and iron concentrations in the tissue of plantar digital arteries. Samples from 31 patients with Blackfoot disease and 30 controls with road traffic accident or occupational injuries were studied.
The results indicate that the arterial tissue from Blackfoot disease patients had higher arsenic concentration (3.06±1.42 μg/g) than that from healthy controls (0.59±0.28 μg/g). The variability was very large 418% at p<0.001. It was also noted that the concentrations of selenium (1.23±0.41 μg/g and 1.05±0.13 μg/g in patients and controls respectively; with variability 17.1%) and iron (72.7±34.9 μg/g and 35.2±16.5 μg/g in patients and controls respectively; with variability 106.5%) were both higher than those of controls. However, only the iron concentration was significantly different (p<0.05).
Copyright © 2001 by Walter de Gruyter GmbH & Co. KG
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- The Impact of Cardiac Natriuretic Peptide Determination on the Diagnosis and Management of Heart Failure
- Models for Combining Random and Systematic Errors. Assumptions and Consequences for different Models
- Nucleosomes in Serum as a Marker for Cell Death
- Comparative Nuclear Magnetic Resonance Studies of Water Permeability of Red Blood Cells from Maternal Venous Blood and Newborn Umbilical Cord Blood
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- Oxidative Stress and Male IGF-1, Gonadotropin and Related Hormones in Diabetic Patients
- New PCR-Based Method for the Sp1 Site Polymorphism in the COL1A1 Gene
- Comparability of Serum and Plasma Concentrations of Haemostasis Activation Markers
- Importance of Validation of Immunoassays for Intact Proinsulin
- Plant Sterol-Enriched Margarine Lowers Plasma LDL in Hyperlipidemic Subjects with low Cholesterol Intake: Effect of Fibrate Treatment
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- Evaluation of Aution Max AX-4280 Automated Urine Test-Strip Analyser
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