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Markers of Endothelial Dysfunction
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Mathias M. Müller
Published/Copyright:
June 1, 2005
Abstract
The endothelium is a functional barrier between vessel wall and blood stream. Assuming the total human vascular and capillary system occupies a surface area of more than 1,000 m2 which is covered by 1013 endothelial cells, the complex role of the endothelium for hemostasis and immunological and metabolic processes becomes obvious. Dysfunction of the endothelium is a critical factor in the pathogenesis of vascular diseases and thrombus formation.
This paper provides a brief review of physiological endothelial functions and summarizes measurable changes in products released from endothelial cells under pathological conditions which were associated with endothelial dysfunction.
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Published Online: 2005-06-01
Published in Print: 2000-02-05
Copyright © 2000 by Walter de Gruyter GmbH & Co. KG
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Articles in the same Issue
- IFCC WorldLab '99
- Markers of Endothelial Dysfunction
- Standardization and Quality Control of PCR Analyses
- Histochemical and Immunocytochemical Approaches to the Study of Oxidative Stress
- Sniffing out the Truth: Clinical Diagnosis Using the Electronic Nose
- Oncogenes and Thyroid Cancer
- Paraneoplastic Syndromes of the Nervous System
- Genetic Modifying Factors in β-Thalassemia
- The Genetics of Multiple Sclerosis
- Near-Infrared Reflectance Spectroscopy for Noninvasive Monitoring of Metabolites
- Ribozyme Gene Therapy for Autosomal Dominant Retinal Disease
- Oxidized Lipoproteins and Endothelium
- Experiences with External Quality Assessment (EQA) in Molecular Diagnostics in Clinical Laboratories in Germany
- Unravelling Genetic Data by Arrayed Primer Extension
- Evaluation of RNA Isolation Methods and Reference Genes for RT-PCR Analyses of Rare Target RNA
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