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Usefulness of Chromogranin A as a Marker for Detection of Relapses of Carcinoid Tumours
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Robert A. Pirker
Published/Copyright:
June 1, 2005
Abstract
It is well known that peptide-producing endocrine tumours cosecrete immunoreactive chromogranin A with their characteristic hormones. Into this study 187 patients with the diagnosis malignant carcinoids or other malignancies were entered. Using chromogranin A at a cut-off level of 30.3 U/ml it was possible to discriminate between patients in remission and patients suffering a relapse with a sensitivity of 91.7% and a specificity of 96.4 %, which may be of important diagnostic value. In our study that lasted over one year we could clearly show that the measurement of chromogranin A is impressively superior to 5-hydroxyindoleacetic-acid for detecting a relapse of carcinoids.
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Published Online: 2005-06-01
Published in Print: 1998-11-01
Walter de Gruyter GmbH & Co. KG
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- Usefulness of Chromogranin A as a Marker for Detection of Relapses of Carcinoid Tumours
- Comparison of Tissue Polypeptide Antigen (TPA) with Cancer Antigen 15-3 (CA 15-3) and Carcino-embryonic Antigen (CEA) in Follow-up of Breast Cancer
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- IFCC Committee on Standardization of Markers of Cardiac Damage: Premises and Project Presentation
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