Chapter 10. Cyclosporine: Synthetic Studies, Structure- Activity Relationships, Biosynthesis and Mode of Action

Chapters in this book

1. Frontmatter I
2. Foreword V
3. Contents VII
4. Chapter 1. Bioactive Peptides - Recent Advances and Trends 1
5. Chapter 2. Gramicidin S Synthetase 33
6. Chapter 3. Formation of TV-methylated Peptide Bonds in Peptides and Peptidols 57
7. Chapter 4. Peptide Bond Synthesis by Enzyme-Catalyzed Acyl-Transfer 81
8. Chapter 5. Genetics of Siderophore Biosynthesis and Transport 103
9. Chapter 6. Discovery of new β-Lactam and β-Lactam like Antibiotics from Bacteria 131
10. Chapter 7. Glycopeptide Antibiotics of the Vancomycin Group 159
11. Chapter 8. Peptide Phytotoxins from Plant Pathogenic Fungi 179
12. Chapter 9. Chemical Synthesis and Bioactivity of Gramicidin S and Related Reptides 205
13. Chapter 10. Cyclosporine: Synthetic Studies, Structure- Activity Relationships, Biosynthesis and Mode of Action 245
14. Chapter 11. Biosynthesis and Chemical Synthesis of Bleomycin 289
15. Chapter 12. Small Molecular Protease Inhibitors and Their Biological Effects 311
16. Chapter 13. Directed Biosynthesis of Neoviridogriseins 365
17. Chapter 14. Biochemical, Genetical and Biotechnical Aspects of Antibiotic Production via Immobilised Biocatalysis 379
18. Chapter 15. Compilation of Peptide Structures - A Biogenetic Approach 411
19. List of Contributors 509
20. Index 511
21. Backmatter 523