Home Physical Sciences 8 Montreal, Canada, June 15–20, 1986
book: 8 Montreal, Canada, June 15–20, 1986
Book
Licensed
Unlicensed Requires Authentication

8 Montreal, Canada, June 15–20, 1986

  • Edited by: B. A. Cooper and V. M. Whitehead
Part of the multi-volume work
Chemistry and Biology of Pteridines
Language: English
Published/Copyright: 1986
Download eBook (PDF)
Become an author with De Gruyter Brill
Explore this Subject How to publish with us

Topics

  • Publicly Available

    Frontmatter

    I
    Download PDF
  • Publicly Available

    Preface

    V
    Bernard A. Cooper and V. Michael Whitehead
    Download PDF
  • Publicly Available

    Acknowledgments

    VII
    Download PDF
  • Publicly Available

    Contents

    IX
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    How it all Began: A Brief History of the Pteridine Symposia

    1
    Adrien Albert
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Gowland Hopkins Lecture: The Mechanisms of Action of Folate and Pterin Requiring Enzymes

    13
    S.J. Benkovic, L.J. Slieker, S.C. Daubner, L.F. Courtney, T.A. Dix, S.O. Pember, L.M. Bloom, C.A. Fierke, R.J. Mayer, J.-T. Chen and K. Taira
    Download PDF
  • Section A: Chemistry of Pterins and Folates
  • Requires Authentication Unlicensed
    Licensed

    Side-Chain Chemistry of Pteridines

    31
    W. Pfleiderer, Y. Kang, R. Soyka, W. Hutzenlaub, M. Wiesenfeldt and W. Leskopf
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    A General Method for the Synthesis of 10-Substituted-10-Deaza Folate Analogues

    45
    M.G. Nair, Tahereh R. Toghiyani, B. Ramamurthy, R.L. Kisliuk and Y. Gaumont
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Synthesis and Properties of Pyrimidodiazepines as Ring-Strained Probes of Pterin Utilizing Enzymes

    51
    S.W. Bailey, D.C. Pike and J.E. Ayling
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Summary: Pterin and Folate Chemistry

    55
    E. C. Taylor
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    A Facile Method for Preparing 2,4-Diamino-5,8-Dideazapterins

    57
    J.B. Hynes, A. Pathak, C.H. Panos and C.C. Okeke
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Synthesis of 5,10-Dideaza-5,6,7,8-Tetrahydrofolic Acid (DDATHF) and Analogs

    61
    Edward C. Taylor, George S. K. Wong, Stephen R. Fletcher, Peter J. Harrington, G. Peter Beardsley and Chuan J. Shih
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Synthetic Routes to Methotrexate- and Folic Acid-Polyglutamates of High Chemical and Enantiomeric Purity

    65
    M. Przybylski, R. Renkel and P. Fonrobert
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    In Vivo and In Vitro Evaluations of 5-[4-(Substituted Aryl)-1- Piperazinyl]-6-Alkyl-2,4-Pyrimidinediamines as Antitumor Agents

    69
    L.M. Werbel, J. Hung, J.A. Besserer, T.J. Boritzki, W.R. Leopold and D.W. Fry
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Electrochemical Oxidation of Tetrahydropterin Derivatives

    73
    S. Kwee
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    A Practical Synthesis of (6R)- and (6S)-5,6,7,8-Tetrahydrobiopterins

    77
    Sadao Matsuura, Takashi Sugimoto and Shizuaki Murata
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Chemical Synthesis and Properties of Quinonoid (6R)-Dihydrobiopterin

    81
    Sadao Matsuura, Shizuaki Murata and Takashi Sugimoto
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Pyrazine-Ring Conformations of Tetrahydropterins and Quinonoid-Dihydropterins

    85
    J. E. Gready
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Hydrogenation of Silylated Pterins in Benzene Solution

    91
    P.H. Boyle and M.J. Kelly
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    N(5)-Alkylation of Polyacetylated 5,6,7,8-Tetrahydroneopterins

    95
    S. Antoulas and M. Viscontini
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Oxidations Photosensitized by Pterins and Diaminopteridines

    99
    M. Aubailly and R. Santus
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Structure of the Riboflavin Synthase/Lumazine Synthase Complex. Arrangement and Chain Folding of Subunits in the Icosahedral Capsid

    103
    R. Ladenstein, H. D. Bartunik, M. Schneider, R. Huber, K. Schott and A. Bacher
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Use of C18 Silica Cartridges to Purify and Characterize Pterins

    107
    K. Bruce Jacobson and J. Ferre
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Synthesis and Structure-Activity Relationships of Tetrahydrobiopterin Cofactor Analogues

    111
    E. C. Bigham, G. K. Smith and J. F. Reinhard
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Synthesis, Purification and Properties of a New Class of Pteridine Derivatives

    115
    J. Ferré, J. J. Yim, W. Pfleiderer and K.B. Jacobson
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Summary: Chemistry of Pterins

    121
    John B. Hynes
    Download PDF
  • Section B: Biosynthesis and Biochemistry of Pterins
  • Requires Authentication Unlicensed
    Licensed

    Biosynthesis of Tetrahydrobiopterin and Related Compounds in Drosophila melanogaster

    125
    G.M. Brown, J.P. Primus and A.C. Switchenko
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Tetrahydrobiopterin Biosynthesis in Man

    141
    H.-Ch. Curtius, S. Takikawa, A. Niederwieser and S. Ghisla
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Biosynthesis of Tetrahydrobiopterin in the Bovine Adrenal Medulla

    151
    Gary K. Smith, David S. Duch and Charles A. Nichol
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Biosynthesis of Tetrahydrobiopterin in Rat Brain

    169
    Sheldon Milstien and Seymour Kaufman
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Summary: Biosynthesis of Tetrahydrobiopterin

    183
    G.M. Brown
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Metabolic Role of Tetrahydrobiopterin

    185
    Seymour Kaufman
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Spectroscopic Studies on Tyrosine 3-Monooxygenase from Bovine Adrenal Medulla: A Blue Iron Protein

    201
    J. Haavik, K.K. Andersson, L. Petersson and T. Flatmark
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Queuine-Lacking tNRAs in Relation to the Grade of Malignancy of Specific Tumors, Possible Role of Pteridines

    205
    W. Kersten, E. Zubrod, B. Emmerich and P. Maubach
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Pteridine Synthesis During Interaction of Interleukin 2 with T Lymphocytes - Modulator Function in IL-2 Signal Transmission

    209
    I. Ziegler, J. Ellwart and U. Schwulera
    Download PDF
  • Section C: Biology of Pterins
  • Requires Authentication Unlicensed
    Licensed

    Dopamine Neurons in Culture: A Model System for Examination of Neuronal Biopterin Metabolism

    215
    Gregory Kapatos and Louis A. Chiodo
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Role of the Pituitary in the Regulation of Tetrahydrobiopterin Biosynthesis in the Non-Neuronal Tissues

    219
    D.S. Duch, S.W. Bowers and C.A. Nichol
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Distribution of GTP Cyclohydrolase-I, Neopterin, and Biopterin in the Human Brain

    223
    T. Nagatsu, M. Sawada, M. Akino, M. Masada, T. Sugimoto and S. Matsuura
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Enzymatic Synthesis of 6,7-Dimethyl-8-Ribityllumazine

    227
    A. Bacher, G. Neuberger and R. Volk
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    A Model for Hyperphenylal aninaemia Due to Tetrahydrobiopterin Deficiency

    231
    R.G.H. Cotton
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Effect of Biopterin and its Reduced Derivatives on Cultured Human Lymphocytes

    235
    S. Webber and D.L. Jaye
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Developmental Aspects of Biopterin Metabolism in Human

    239
    J.L. Dhondt, J.M. Hayte, G. Forzy, M. Delcroix, J.P. Farriaux and C. Largillière
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Screening for Biopterin Defects Among Hyperphenylalaninemic Patients: Report of a Canadian Program After 3 Years

    243
    F. Mohyuddin, C.A. Rupar and M.C. Evers
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Need for Therapy in utero of Fetuses with Tetrahydrobiopterin Deficiency

    247
    Y. Sawada, H. Shintaku, I. Suyama, G. Isshiki, Y. Hase, Y. Okano, H. Yamamoto, T. Tsuruhara and T. Oura
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Pteridine Metabolism in Patients Suffering from Amyotrophic Lateral Sclerosis

    251
    H.-J. Zeitler, B. Andondonskaja-Renz, G. Küther and A. Struppler
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Urinary Neopterin in Cocaine-Abusing Individuals

    257
    R.W. Guynn, K. Biehl, D.K. Merrill and K.J. Krajewski
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Features of Neopterin Determination in Clinical Use

    263
    E.R. Werner, D. Fuchs, A. Hausen, G. Reibnegger, H. Wachter and J.F.K. Huber
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Diurnal Variation in Urinary Pterin Excretion in Man

    267
    Anne E. Pheasant
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Relationship between Pteridines and Colour Dimorphism in the Scorpion Fly

    271
    M. Tsusué and M. Nakagoshi
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Pteridine Biosynthesis and Manifestation of Pigment Phenotypes in Normal and Neoplastic Cells of Goldfish in Vitro

    275
    M. Masada, J. Matsumoto and M. Akino
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Light Depending Regulations of Pteridines in the Retina

    279
    G. Cremer-Bartels and K. Krause
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Differences in the Regulation of Tetrahydrobiopterin Biosynthesis in Neuronal Cells in Culture

    283
    J. H. Woolf, C. A. Nichol and D. S. Duch
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    NADPH- and NADH-Specific Dihydropteridine Reductase in Teratocarcinoma Cells in Culture: Effect of Nerve Growth Factor Treatment of the Cells on the Enzyme Activities

    287
    Nobuo Nakanishi, Kenichi Ozawa, Shozo Yamada, Kaoruko Akiba and Naoyoshi Sato
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Reversibility of α-Diketo Reductase Activity by Sepiapterin Reductase

    291
    S. Katoh, T. Sueoka and S. Yamada
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Non-Enzymatic Synthesis of "Drosopterins" from Dihydropterin and 2-Amino-4-0xo-6-Acetyl-3H, 9H-7,8-Dihydropyrimido [4,5b] [1,4]Diazepine

    295
    D. R. Paton and G. M. Brown
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    BH4 Biosynthesis: 1H-NMR Evidence for the Pyruvoyl-Tetrahydropterin-Synthase Catalyzed Formation of 6-Pyruvoyl-Tetrahydropterin from Dihydroneopterin Triphosphate

    299
    S. Ghisla, S. Takikawa, P. Steinerstauch, Th. Hasler and H.-Ch. Curtius
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Catabolism of Tetrahydrobiopterin in Man

    305
    A. Niederwieser, A. Matasović, Th. Kuster, W. Staudenmann, W. Pfleiderer and Susanne Scheibenreiter
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Pteridine Biosynthesis in Human Amniocytes and Chorionic Villi

    309
    J. Ferré and E.W. Naylor
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Role of the Kidney in Biopterin Metabolism

    315
    J.L. Dhondt, J.M. Hayte, C. Noël, M. Dracon, G. Lelievre and A. Tacquet
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Tetrahydrobiopterin-Producing Enzyme Activities in Liver of Animals and Man

    319
    Th. Hasler and A. Niederwieser
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Effect of 3-Hydroxykynurenine on GTP Cyclohydrolase Activity and on the Pteridine Pattern in Drosophila melanogaster

    323
    Francisco J. Silva and José L. Ménsua
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Tetrahydrobiopterin Metabolism in Normal Brain, Senile Dementia of the Alzheimer Type and Down's Syndrome

    327
    J.M. Anderson, C.G.B. Hamon, R.A. Armstrong and J.A. Blair
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Summary: Biology of Pteridines

    331
    M.A. Parniak
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Biosynthesis of Pteridines and Metabolism of Aromatic Amino Acids in Drosophila melanogaster

    335
    Y. Bel and J. Ferré
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Inhibition of tRNA Transglycosylases by Pteridines as a Mean for Metabolic Control of Gene Expression

    339
    H. Kersten, H.-J. Aschhoff, P. Böhm and E. Zubrod
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Modulation of Dopamine Synthesis by Nerve Terminal Autoreceptors: A Role for Tetrahydrobiopterin?

    347
    Matthew P. Galloway and Robert A. Levine
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    A Monoclonal Antibody Reacting with All Three Aromatic Amino Acid Hydroxylases

    351
    R.G.H. Cotton, I.G. Jennings, R. Kuskinsky, C.W. Chow, E. Haan, W.J. McAdam, C. Bell, F. Morgan, H. Nakata and A.C. Cuello
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Alterations in Cofactor-Dependent Activity of Phenylalanine Hydroxylase as a Function of pH

    355
    M.A. Parniak and S. Kaufman
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Interaction of a Monoclonal Antibody with Rat Liver Phenylalanine Hydroxylase

    359
    M.A. Parniak, I.G. Jennings and R.G.H. Cotton
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Effect of Dietary Iron on the Activity of Rat Liver Phenylalanine Hydroxylase

    363
    Michael D. Davis and Seymour Kaufman
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Strict Requirement of Fe2+ for Tryptophan 5-Monooxygenase from Mouse Mastocytoma, P-815

    369
    Hiroyuki Hasegawa and Arata Ichiyama
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Tetrahydrobiopterin and the Regulation of Catecholamine Synthesis in Bovine Adrenal Medullary Chromaffin Cells

    373
    Robert A. Levine and Katrina L. Kelner
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Cofactor Activity of Tetrahydropterins for Tyrosine Hydroxylation in PC12 Pheochromocytoma Cells

    377
    D.S. Duch, J.F. Reinhard, M.P. Edelstein, J.Y. Chao and C.A. Nichol
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Summary: Pterin-Dependent Biological Reactions

    381
    Robert A. Levine
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Tetrahydrobiopterin Deficiency. Analysis from an International Survey

    385
    Jean-Louis Dhondt
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Cofactor Specificity of 6,6-Disubstituted Tetrahydropterins, and their Potential in the Treatment of Neurological Disorders

    391
    J.E. Ayling, S.W. Bailey and S.B. Dillard
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Normal Concentrations of Tetrahydrobiopterin in the Cerebrospinal Fluid of Patients with Dihydropteridine Reductase Deficiency

    395
    K. Hyland, I. Smith and D. W. Howells
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Prenatal Diagnosis of Tetrahydrobiopterin Deficiency

    399
    A. Niederwieser, H. Shintaku, Th. Hasler, H.-Ch. Curtius, H. Lehmann, D. Leupold, O. Guardamagna, A. Ponzone and H. Schmidt
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Defective Biopterin Biosynthesis in a Chinese Infant

    403
    C.R. Scriver, C.L. Clow, P. Kaplan, G.V. Watters, C. Laberge, Fazl Mohyuddin and S. Milstien
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Correlation of Dihydropterine Reductase Cross Reacting Material with Non-Responsiveness to a Tetrahydrobiopterin Load

    407
    R.G.H. Cotton, I.G. Jennings, G. Bracco, A. Ponzone and O. Guardamagna
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Neopterin and Dihydroneopterins in Serum of Controls and Patients with Various Diseases. Circadian Rhythm of Neopterin. Influence of Cortisol?

    411
    H. Rokos, Hildegard Frisius and R. Kunze
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Neopterin Content and GTP-Cyclohydrolase Activity of Blood Cells of Controls and Patients Positive for LAV/HTLV-III Antibodies

    415
    K. Rokos, R. Kunze, W. Lange and M.A. Koch
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Neopterin in Bone Marrow Transplant Monitoring: An Improvement in its Use for GVHD Diagnosis

    419
    P. Mura, A. Piriou, D. Reiss, F. Guilhot, E. Benz-Lemoine and J. Tanzer
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Importance of Neopterin Determination in Individuals at Risk for AIDS

    427
    D. Fuchs, A. Hausen, G. Reibnegger, E.R. Werner, H. Wachter, H.G. Blecha, H. Roessler, B. Unterweger, H. Hinterhuber, P. Hengster, T. Schulz, M.P. Dierich and D. Renner
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Biochemical Aspects of Pteridines During Interaction Between Activated T-Lymphocytes and Monocytes/Macrophages in Patients

    431
    B. Andondonskaja-Renz and H.-J. Zeitler
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Summary: Pterins and Human Illness

    443
    D. Fuchs and H. Wachter
    Download PDF
  • Section D: Folates and Pterins in Mammalian Tissues
  • Requires Authentication Unlicensed
    Licensed

    Folates in Tissues and Cells. Support for a "Two-Tier" Hypothesis of Regulation of One-Carbon Metabolism

    447
    Carlos L. Krumdieck and Isao Eto
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Elevation in the Rate of Cellular Folate Catabolism in Mid-Pregnancy in the Rat

    467
    J.M. Scott, E. Wilson and D.G. Weir
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Red Blood Cell as a Storage Site for Folic Acid

    471
    Stephen E. Steinberg
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Methotrexate and Biopterin Levels in Blood Following Low Dose Administration for Psoriasis

    475
    R.J. Leeming, R.M. Conlon, A. Pollock and J. Kumari
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Summary: Folates in Tissue and Cells

    479
    D.G. Priest
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Folate Rescue of N2O-Induced Inhibition in Murine Lymphocytes

    481
    J. G. Hilton, B. A. Cooper and W. Lapp
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Folate Absorption and Metabolism in Alcohol Fed Rats

    485
    J.M. Noronha and V. Kesavan
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Chronic and Acute Effects of Ethanol on Renal Clearance and Urinary Excretion of Folate in Rats

    489
    K.E. McMartin, B.H. Eisenga, T.D. Collins and L. Bairnsfather
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Effect of Chronic Anticonvulsant Treatment on Folate Concentrations in the Rat

    495
    G.F. Carl
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Alcohol Induced Methyl Group Wastage as a Possible Cause of Fatty Liver

    505
    A.M. Molloy, J.M. Scott and D.G. Weir
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Folate Catabolism in the Syrian Golden Hamster

    509
    D. Al-Haddad, A.E. Pheasant, J.A. Blair and C.G.B. Hamon
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Level of Folate Catabolism in Normal Human Populations, Suggesting that the Current Level of RDA for Folate is Excessive

    513
    J.M. McPartlin, D.G. Weir, G. Courtney, H. McNulty and J.M. Scott
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Microdetermination of Folate Monoglutamates in Serum by High-Performance Liquid Chromatography with Electrochemical Detection

    517
    K. Iwai, K. Inoue and M. Kohashi
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Folate Status in Psychiatric Patients: Relationship with CSF Neurotransmitter Metabolites

    523
    T. Bottiglieri, M. Laundy, M.W.P. Carney, T.K.N. Chary, B.K. Toone and E.H. Reynolds
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Folate, Thiamine and Vitamin B12 Levels in Outpatient Epileptics

    527
    M. I. Botez
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Effect of Aspirin Ingestion on Folate Bioavailability Evaluated by Rat Liver Bioassay

    531
    K. Hoppner and B. Lampi
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Brush Border Pteroylpolyglutamate Hydrolase in Pig Jejunum

    539
    C.J. Chandler, T.T.Y. Wang and C.H. Halsted
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Use of CI-920 in the Characterization of the Methotrexate Transport Defect in a Resistant Human Leukemic CCRF-CEM Cell Line

    543
    G. Jansen, J.H. Schornagel, G. Rijksen and J. de Gier
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Effect of Oxidative Stress on Methotrexate (MTX) Transport by Rat Hepatocytes

    547
    Myung S. Rhee, Aiga Pupons, Zenia Nimec and John Galivan
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Folate Transport by Pig Intestinal Brush Border Vesicles

    551
    A.M. Reisenauer
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Depressed Folate Transfer Across the Mammary Gland Secondary to Iron Deficiency in the Rat

    555
    D.L. O’Connor, M.F. Picciano, A.R. Sherman and S.L. Burgert
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Studies on the Mechanism of Folate Transport in Isolated Hepatocytes

    559
    Donald W. Horne
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Analysis of the pH and Na+ Dependence of Intestinal Folate Transport

    563
    I.H. Rosenberg, J. Zimmermann and J. Selhub
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Intestinal Transport of Folate. Characterization of the Transport Events at the Brush Border and the Basolateral Membranes

    567
    H. M. Said and W. B. Strum
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Synthesis of Some Novel Probes of Folate Transport and Binding

    571
    Robert J. Kempton, Laura A. Sams, Kathleen M. Harpring, Amy G. Smith, Frank Kohrs, Elmer Price and James H. Freisheim
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Photoaffinity Probes of Dihydrofolate Reductase and of the Membrane Carrier for Folate Analogues

    575
    E.M. Price, P.L. Smith and J.H. Freisheim
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Use of Biosynthetic Radioactive Folylpolyglutamates to Study Intestinal Digestion and Absorption of Folate

    579
    B. Darcy-Vrillon, J. Selhub and I.H. Rosenberg
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Selective Inhibition of Bacterial Carboxypeptidase G and Pancreatic Conjugase by 2-Mercaptomethylglutaric Acid

    583
    T.I. Kalman, V.K. Nayak and A.R.V. Reddy
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Summary: Folate Absorption and Transport

    587
    I.H. Rosenberg
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Studies on Glycine-N-Methyltransferase

    593
    Conrad Wagner and Robert J. Cook
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Folate Binding Protein from Pediococcus Cerevisiae Strains Possessing Active Transport Systems for Folates

    597
    Frederika Mandelbaum-Shavit
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Immobilized Folate Binding Protein from Cow's Milk Used for Quantitation of Folate

    603
    S.I. Hansen, E. Nexø and J. Holm
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Characterization of Rabbit Antibodies Against the Folate Binding Protein from Cow's Milk

    607
    M. Høier-Madsen, S.I. Hansen and J. Holm
    Download PDF
  • Section E: Enzymology of Folates
  • 1. Thymidylate Synthase
  • Requires Authentication Unlicensed
    Licensed

    Genetic and Chemical Studies on Thymidylate Synthase

    613
    Frank Maley, Frederick K. Chu, Deborah K. West and Gladys F. Maley
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Active Site Probes of Thymidylate Synthetase

    631
    Arthur D. Broom and In-Young Yang
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Resonance-Raman Spectroscopic Identification of the Transient Intermediates Formed in the Native Ternary Complex with Thymidylate Synthase

    639
    A.L. Fitzhugh, S. Kaufman, S. Fodor and T.G. Spiro
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Reversal of the Cytotoxicity of Folate-Based Thymidylate Synthase Inhibitors in Cultures L1210 Cells

    645
    A.L. Jackman, A.H. Calvert and R.G. Moran
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Thymidylate Synthase Activity in the Tapeworm, Hymenolepis diminuta

    651
    J. Cieśla, Z. Zieliński, W. Rode and B. Machnicka
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Identification of Poly G Bound to Thymidylate Synthase

    655
    J. Thorndike and R.L. Kisliuk
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Methotrexate Derivates of Deoxyuridylate Showing Inhibitory Properties for Thymidylate Synthetase from Lactobacillus casei

    659
    S. Webber, R. Nazarbaghi and J.M. Whiteley
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Comparison of Thymidylate Synthase Isolated from Mouse Normal and Tumour Tissues

    663
    Z. Zieliński, J. Cieśla, B. Kędzierska and W. Rode
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Thymidylate Synthase Interaction with Analogues of dUMP and 5-Fluorid- 2'-Deoxyuridine-5'-Phosphate with Modified Phosphate Groups

    667
    W. Rode, B. Kędzierska, T. Kulikowski and D. Shugar
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    An In Vitro System for Studies on Inhibition of the Thymidylate Cycle

    671
    H. Rebandel, Y. Gaumont and R.L. Kisliuk
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    N10-Propargyl-5,8-Dideazafolic Acid Polyglutamates as Inhibitors of Thymidylate Synthase and their Intracellular Formation

    675
    E. Sikora, A.L. Jackman, D.R. Newell, K.R. Harrap, A.H. Calvert, T.R. Jones, K. Pawelczak and B. Rzeszotarska
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Sequential CMF in Metastatic Breast Cancer: An Attempt to Increase Effectiveness by Means of Biochemical Modulation

    681
    P. Pronzato, L. Repetto, D. Amoroso, A. Ardizzoni, G. Bertelli, P.F. Conte, V. Fusco, M. Gulisano and R. Rosso
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Model Studies of Thymidylate Synthase Reaction

    687
    Paul F.C. van der Meij, Ellen Hilhorst, Tjoe B.R.A. Chen, Eduard R. de Waard and Upendra K. Pandit
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Synergistic Interaction Between Folinic Acid and the Fluoropyrimidines

    691
    Khandan Keyomarsi and Richard G. Moran
    Download PDF
  • 2. Methionine Biosynthesis
  • Requires Authentication Unlicensed
    Licensed

    Methionine Biosynthesis

    697
    Rowena G. Matthews, David A. Jencks, Verna Frasca and Keith D. Matthews
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Impaired Formylation and Uptake of Tetrahydrofolate by Rat Small Gut Following Cobalamin Inactivation

    709
    Janet Perry, Rosemary Deacon, M. Lumb and I. Chanarin
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Heterogeneity in Functional Methionine Synthase Deficiency

    713
    David Watkins and David S. Rosenblatt
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Summary: Methionine Biosynthesis

    717
    E. L. R. Stokstad
    Download PDF
  • 3. Folyl Polyglutamate Synthetase
  • Requires Authentication Unlicensed
    Licensed

    Folylpoly-γ-glutamate Synthetase

    719
    B. Shane
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Cytotoxic Effects and Inhibition of Folylpolyglutamate Synthetase by Folate Analogs Containing 2, Omega-Diaminoalkanoic Acids

    729
    John J. McGuire and James R. Piper
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    An Upstream Gene Regulates the Expression of Folylpolyglutamate Synthetase-Dihydrofolate Synthetase in Escherichia coli

    733
    Andrew L. Bognar, Charles Osborne and Barry Shane
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Occurence and Synthesis of Pteroyl-γ-glutamyl-γ-glutamyl-poly-α-glutamates in Escherichia coli

    737
    R. Ferone, M. Hanlon, S. Singer and D. Hunt
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Summary: Folylpolyglutamate Synthesis

    741
    Edwin A. Cossins
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Metabolism of Pteroylpolyglutamates

    743
    Roy L. Kisliuk
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Dihydropteroyl Hexaglutamate and T4 Phage Baseplate Assembly

    757
    Boguslaw Szewczyk, Krystyna Szewczyk and Lloyd M. Kozloff
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Effects of Polyglutamylation on Folate Cofactor and Antifolate Activity in the Thymidylate Synthase Cycle of Permeabilized Murine Leukemia L1210 Cells

    763
    Thomas I. Kalman
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Summary: Pteroylpolyglutamate metabolism

    767
    R. E. MacKenzie
    Download PDF
  • 4. Dihydrofolate Reductase
  • Requires Authentication Unlicensed
    Licensed

    Recent Advances in the Study of Dihydrofolate Reductase

    769
    Raymond L. Blakley and James R. Appleman
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The 2.8 Å Structure of a Type II Plasmid Encoded Dihydrofolate Reductase

    789
    D.A. Matthews, S.L. Smith, D.P. Baccanari, J.J. Burchall, S.J. Oatley and J. Kraut
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Mutations in the Human Dihydrofolate Reductase

    793
    B. I. Schweitzer, S. Srimatkandada, S.K. Dube and J.R. Bertino
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Theoretical Studies of the Structure, Conformational and Electronic Properties of Anticancer Folate Inhibitors

    799
    W.J. Welsh and V. Cody
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Binding of Inhibitors with Spin-Labeled Side Chains to Dihydrofolate Reductase (DHFR) from Several Species

    803
    R.L. Blakley, R.F. Kulinski, J.R. Appleman and J.R. Piper
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Affinity Labeling of Dihydrofolate Reductase with an Iodoacetyl Lysine Analogue of Methotrexate

    807
    T.J. Delcamp, A. Rosowsky, P.L. Smith, J.E. Wright and J.H. Freisheim
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Escherichia coli Dihydrofolate Reductase Isolated as a Folate Complex

    811
    S.S. Joyner and D.P. Baccanari
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Dihydrofolate Reductase from Soybean Seedlings

    815
    S. Ratnam, T.J. Delcamp and J.H. Freisheim
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Use of Antibodies as Structural Probes of Dihydrofolate Reductases and Enzyme-Ligand Complexes

    819
    M. Ratnam, T.J. Delcamp and J.H. Freisheim
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Cooperativity in Inhibitor Binding to Neisseria gonorrhoeae Dihydrofolate Reductase

    823
    Robert L. Tansik and David P. Baccanari
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    pH Studies of the Reaction Catalyzed by Dihydrofolate Reductase from E. coli

    827
    John F. Morrison and Stuart R. Stone
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Effects of pH on Reactions Catalyzed by Dihydrofolate Reductase from Chicken Liver

    831
    John F. Morrison and Stuart R. Stone
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Unconjugated Dihydropterin Substrates for Bovine Liver Dihydrofolate Reductase

    835
    G.K. Smith, S.D. Banks, E.C. Bigham and C.A. Nichol
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Enzymatic Characterization of Recombinant Human Dihydrofolate Reductase Produced in E. coli

    839
    D. Stüber, H. Bujard, E. Hochuli, H.P. Kocher, I. Kompis, K. Talmadge, E.K. Weibel, F.K. Winkler and R.L. Then
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Levels of Folates and Methotrexate Polyglutamate Formation in Chinese Hamster Ovary Cells Lacking Dihydrofolate Reductase

    843
    P. Joannon, H. Goldberg, V.M. Whitehead, D.S. Rosenblatt, M.J. Vuchich and D. Beaulieu
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Methotrexate in Adjuvant Arthritis

    847
    John Galivan, Mary-Catherine Rehder and Suresh Kerwar
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Computer Graphic Modeling in Drug Design: Conformational Analysis and Active-Site Modeling of Lipophilic Diaminopyrimidines

    851
    Vivian Cody
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Effect of Antifolates 10-Methyl- and 10-Ethyl-10-Deaza-Aminopterin on a Human Breast Cancer Cell Line

    855
    Frederika Mandelbaum-Shavit
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Biochemical and Cytotoxic Effects of the Erythro- and Threo-Isomers of Gamma-Fluoro-Methotrexate

    861
    John J. McGuire, John Galivan and James K. Coward
    Download PDF
  • 5. Other Folate Enzymes
  • Requires Authentication Unlicensed
    Licensed

    C1-Tetrahydrofolate-Synthase, a Multifunctional Enzyme Involved in Purine Metabolism, and its Related Monofunctional Enzymes

    865
    K.W. Shannon, T.R. Whitehead, C. Staben and J.C. Rabinowitz
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Interaction of Tetrahydropteroylpolyglutamates with 10-Formyltetra-Hydrofolate Synthetase

    887
    V. Schirch, B. Strong, G. Joshi, R. Lura and T. Dennis
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Summary: Folates in C 1 Metabolism

    891
    V. Schirch
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Chemical Aspects of Dimethylglycine Dehydrogenase and Sarcosine Dehydrogenase

    893
    Robert J. Cook, Peter Gettins and Conrad Wagner
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Folate Normalizes Elevated PRPP Levels of Folate-Deficient HL-60 Cells

    897
    J. Ghitis, C. Schreiber and S. Waxman
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Stereochemistry of Hydride Transfer to NADP+ by Methylene Tetrahydrofolate Dehydrogenase from Pig Liver

    901
    Jacalyn Green, Rowena G. Matthews and Robert E. MacKenzie
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Effects of Thyroxine Status on Hepatic Levels of 10-Formyltetrahydrofolic Acid: NADP Oxidoreductase

    905
    J.M. Keating, H. Choe and E.L.R. Stokstad
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Interaction of Homocysteine with Methionine Synthetase

    909
    Garry P. Lewis
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Minor Form of Human Hepatic Betaine: Homocysteine S-Methyltransferase

    913
    William E. Skiba, Marilyn S. Wells, John H. Mangum and William M. Awad
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Studies of Cobalamin-Dependent Methionine Synthase from Escherichia coli B

    917
    Verna Frasca, William R. Dunham, Richard H. Sands, Barbara Stephenson Riazzi and Rowena G. Matthews
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Inhibition of Methylenetetrahydrofolate Reductase by Adenosyl Methionine

    921
    David A. Jencks and Rowena G. Matthews
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Regulation of Folate Homeostasis

    925
    C. Osborne, K. Lowe, B. Shane, D. J. Cichowicz, D. Sussman and G. Milman
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    An Endogenous Inhibitor of Neurospora Folylpolyglutamate Synthetase

    929
    E.A. Cossins and P.Y. Chan
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Folylpolyglutamate Hydrolase from Beef Liver

    933
    P. J. Vickers, R. Di Cecco, Z. B. Pristupa and K. G. Scrimgeour
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Use of Mammalian Cell Transformation to Isolate Genomic Sequences Encoding Human Folylpolyglutamate Synthetase (FPGS) and Dihydrofolate Reductase (DHFR)

    937
    Shirley M. Taylor, Norman Davidson and Richard G. Moran
    Download PDF
  • Section F: Methotrexate and Other Anti-Folates
  • Requires Authentication Unlicensed
    Licensed

    Antifolates: Expanding Horizons in 1986

    945
    Bruce A. Chabner, Carmen J. Allegra and Jacob Baram
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Deaza Derivatives of Tetrahydrofolic Acid. A New Class of Folate Antimetabolite

    953
    G. Peter Beardsley, Edward C. Taylor, Gerald B. Grindey and Richard G. Moran
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Structure Activity Relationships of Novel Triazine Antifolates

    959
    C. Dias Selassie, C. Hansch, Y.C. Zheng, H. Zhu, T. Khwaja, J. Freisheim and T.J. Delcamp
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Effect of 7-Hydroxymethotrexate on the Antitumor Activity and Host Toxicity of Methotrexate In Vivo

    963
    P.A. Newton, R.A. Finch and T.L. Avery
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Summary: The Biology of Antifolates

    967
    J. Gallivan
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Crystal Structure of Methotrexate and its Conformational Comparison with Related Structures

    969
    Paul A. Sutton and Vivian Cody
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Effect of Methotrexate on Reduced Folates and Thymidylate Synthesis During Growth of L1210 Cells

    973
    D.G. Priest, V. Kesavan and M.T. Doig
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Dihydrofolate Reductase from Human Osteosarcoma Cells Resistant to Methotrexate

    977
    Judith K. Sato and Theodore J. DeFrank
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Evidence for Direct Inhibition of Metabolic Pathways as a Mechanism of Action of Methotrexate

    981
    C.J. Allegra, J. Baram and B.A. Chabner
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Inhibition of Dihydrofolate Reductase and Thymidylate Synthase by Methotrexate Polyglutamate Analogues Lacking "Internal" α-Carboxyl Groups

    985
    A. Rosowsky, R.A. Forsch, M.M. Wick, J.H. Freisheim, P.V. Danenberg and T.I. Kalman
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    The Antifolate Activity of Poly-γ-Glutamyl Derivatives of Methotrexate, 10-Deazaaminopterin and 10-Ethyl-10 Deazaaminopterin

    989
    R.L. Kisliuk, Y. Gaumont, P. Kumar, M.G. Nair and B.T. Kaufman
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Polyglutamation of the Thymidylate Synthase Inhibitor, N10-Propargyl-5,8-Dideazafolic Acid (CB 3717), in Organs of Ehrlich Ascites Carcinoma-Bearing Mice

    993
    M. Manteuffel-Cymborowska, B. Kamińska and B. Grzelakowska-Sztabert
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    5,8-Dideazafolates as Substrates for Folypoly-γ-Glutamate Synthetase from Pig Liver

    997
    J. B. Hynes, D. J. Cichowicz and B. Shane
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    5-Substituted-5-Deaza Analogues of Classical Antifolates

    1001
    J. R. Piper, G. S. McCaleb, J. A. Montgomery and F. M. Sirotnak
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Azido-Substituted Antifolate Drugs: Synthesis, Structure, and Activity

    1005
    P.K. Bryant, K.P. Wong, J. Colby, C.H. Schwalbe, M.F.G. Stevens, R.J. Griffin and E.A. Bliss
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Summary: Novel Antifolates

    1009
    Robert C. Jackson
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Author Index

    1011
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Subject Index

    1017
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    List of Participants

    1033
    Download PDF
  • Requires Authentication Unlicensed
    Licensed

    Backmatter

    1051
    Download PDF

Publishing information
Pages and Images/Illustrations in book
eBook published on:
July 22, 2019
eBook ISBN:
9783110856262
Hardcover published on:
October 1, 1986
Hardcover ISBN:
9783110107715
Edition:
Reprint 2019
Pages and Images/Illustrations in book
Front matter:
28
Main content:
1050
Other:
Num. figs.
https://doi.org/10.1515/9783110856262
eBook ISBN: 9783110856262
Hardcover ISBN: 9783110107715
Safety & product resources
Sign up now to receive a 20% welcome discount
Institutional Access
How does access work?
Winner of the OpenAthens UX Award 2026
Winner of the OpenAthens UX Award 2026
Have an idea on how to improve our website?
Please write us.
© 2026 De Gruyter Brill
Downloaded on 6.3.2026 from https://www.degruyterbrill.com/document/doi/10.1515/9783110856262/html
Scroll to top button