9. Control of cell growth by nitric oxide: the role of cGMP-dependent and -independent events occurring at various steps of growth factor-activated signalling processes

Chapters in this book

1. Frontmatter i
2. Contents v
3. Preface ix
4. Contributors xi
5. Abbreviations xxi
6. 1. Nitric oxide, mitochondria and cytotoxicity 1
7. 2. Nitric oxide and its congeners in mitochondria: implications for apoptosis 11
8. 3. Interactions between nitric oxide and cytochrome-c oxidase in turnover 23
9. 4. Nitric oxide interactions with mitochondria and oxygen metabolism 31
10. 5. Resistance factors for nitrosative and oxidative stress 41
11. 6. S-Nitrosylation of thiol groups in haemoglobins from various species 47
12. 7. Differential inhibitory action of nitric oxide and peroxynitrite on the R2 subunit of ribonucleotide reductase 60
13. 8. Hydroxyguanidines as modifiers of cell proliferation and death: a possible role for nitric oxide 71
14. 9. Control of cell growth by nitric oxide: the role of cGMP-dependent and -independent events occurring at various steps of growth factor-activated signalling processes 81
15. 10. Nitric oxide controls cell proliferation during Drosophila development 93
16. 11. Cytoprotective actions of nitric oxide in hepatic inflammation 99
17. 12. Activation of nuclear factor-κB and activator protein- I, and steady-state level of mRNA encoding tumour necrosis factor-α and inducible nitric oxide synthase in rat liver during different types of cell proliferation 107
18. 13. The mechanism of nitric oxide-induced apoptosis in the pancreatic β-cell may involve cGMP and protein kinase G 113
19. 14. Normal and pathological expression of nitric oxide synthase in the central nervous system 123
20. 15. The role of astroglial cell-derived nitric oxide and prostanoids in death and repair mechanisms in the brain 135
21. 16. Role of nitric oxide and nerve growth factor in the mechanisms of neurotoxicity induced by the HIV-1 coat protein gp l 20 in rat 145
22. 17. Mechanisms of neurotoxicity induced by the HIV-1 coat protein, gp l 20, in human neuroblastoma cells in culture 155
23. 18. Nitric oxide mediates differentiation and survival of neuronal cells 169
24. 19. Neuromodulatory and neuroprotective actions of nitric oxide in the striatum 177
25. 20. Microdialysis study in vivo of the nitric oxide/cGMP pathway in the hippocampus and cerebellum of adult and aged rats 191
26. 21. Mechanisms of neuronal apoptosis elicited by glutamate or nitric oxide donors 213
27. 22. Evidence that nitric oxide induces apoptotic cell death in the lateral geniculate nucleus of dark-reared rabbits 219
28. 23. Nitric oxide and prostaglandins in inflammation 227
29. 24. A further insight into the mechanism of lipoxygenase inhibition by nitric oxide 235
30. 25. The role of nitric oxide in T-cell functions 243
31. 26. CD95-induced calcium release and apoptosis are regulated by nitric oxide via a cGMP dependent pathway in human γδ T-lymphocytes 247
32. 27. Nitric oxide-initiated apoptotic cell death: activating and antagonistic signalling components 257
33. 28. Nitric oxide-induced apoptosis of RAW264.7 peritoneal macrophages: relationship between apoptosis and integrin expression profiles 269
34. 29. Nitric oxide, p53 and cancer 275
35. 30. The role of nitric oxide in Bacillus Calmette-Guérin-mediated anti-tumour effects in human bladder cancer 281
36. 31. Nitric oxide priming inhibits nitric oxide-mediated apoptosis 291
37. Subject Index 299