Yale University Press
Wetware
About this book
How does a single-cell creature, such as an amoeba, lead such a sophisticated life? How does it hunt living prey, respond to lights, sounds, and smells, and display complex sequences of movements without the benefit of a nervous system? This book offers a startling and original answer.
In clear, jargon-free language, Dennis Bray taps the findings of the new discipline of systems biology to show that the internal chemistry of living cells is a form of computation. Cells are built out of molecular circuits that perform logical operations, as electronic devices do, but with unique properties. Bray argues that the computational juice of cells provides the basis of all the distinctive properties of living systems: it allows organisms to embody in their internal structure an image of the world, and this accounts for their adaptability, responsiveness, and intelligence.
In Wetware, Bray offers imaginative, wide-ranging and perceptive critiques of robotics and complexity theory, as well as many entertaining and telling anecdotes. For the general reader, the practicing scientist, and all others with an interest in the nature of life, the book is an exciting portal to some of biology’s latest discoveries and ideas.
Topics
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Frontmatter
i -
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Contents
vii -
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Preface
ix -
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One. Clever Cells
1 -
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Two. Simulated Life
27 -
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Three. Protein Switches
54 -
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Four. Protein Signals
71 -
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Five. Cell Wiring
89 -
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Six. Neural Nets
109 -
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Seven. Cell Awareness
132 -
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Eight. Molecular Morphing
144 -
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Nine. Cells Together
167 -
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Ten. Genetic Circuits
179 -
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Eleven. Robots
195 -
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Twelve. The Juice
209 -
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Thirteen. Amoeba Redux
226 -
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Glossary
243 -
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Sources and Further Reading
251 -
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Index
259