There is ample evidence that language users, including second-language (L2) users, can predict upcoming information during listening and reading. Yet it is still unclear when, how, and why language users engage in prediction, and what the relation is between prediction and learning. This volume presents a collection of current research, insights, and directions regarding the role of prediction in L2 processing and learning. The contributions in this volume specifically address how different (L1-based) theoretical models of prediction apply to or may be expanded to account for L2 processing, report new insights on factors (linguistic, cognitive, social) that modulate L2 users’ engagement in prediction, and discuss the functions that prediction may or may not serve in L2 processing and learning. Taken together, this volume illustrates various fruitful approaches to investigating and accounting for differences in predictive processing within and across individuals, as well as across populations.