Abstract
Background: To evaluate the diagnostic value of the 3rd hour plasma glucose level in the 100 g oral glucose tolerance test (OGTT).
Methods: Records of all pregnant patients with abnormal 50 g glucose challenge test (GCT) between January 2005 and December 2013 were reviewed (n=1963). The 100 g OGTT results were analyzed separately for both Carpenter & Couston (CC) and National Diabetes Data Group (NDDG) criteria.
Results: The number of patients diagnosed with gestational diabetes mellitus (GDM) was 297 (15.1%) according to CC criteria and 166 (8.4%) according to NDDG criteria. The 1st hour plasma glucose level showed the highest correlation with GDM diagnosis (ρ=0.595 for CC and ρ=0.567 for NDDG). However, the 3rd hour plasma glucose level showed the weakest correlation with GDM diagnosis (ρ=0.216 for CC and ρ=0.213 for NDDG). The 3rd hour value of 100 g OGTT was one of the two elevated measurements in 10.8% of patients when CC criteria are used and in 13.8% of patients when NDDG criteria are used.
Conclusion: Omitting 3rd hour plasma glucose measurement in 100 g OGTT results in unacceptable rates of underdiagnosed patients.
References
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The authors stated that there are no conflicts of interest regarding the publication of this article.
©2016 by De Gruyter
Articles in the same Issue
- Frontmatter
- Editorial
- Obesity and gestational diabetes in pregnancy: an evolving epidemic
- Original articles - Diabetes
- Is omitting the 3rd hour measurement in the 100 g oral glucose tolerance test feasible?
- Maternal hypoglycemia on 50 g glucose challenge test: outcomes are influenced by fetal gender
- Biological and biochemical characteristics of a Mediterranean population with Gestational Diabetes Mellitus
- Maternal and perinatal outcomes after bariatric surgery: a case control study
- A population-based comparison between actual maternal weight gain and the Institute of Medicine weight gain recommendations in singleton pregnancies
- The relationship between cesarean section rate in term singleton pregnancies, maternal weight, and weight gain during pregnancy
- Antenatal body mass index (BMI) and weight gain in pregnancy – its association with pregnancy and birthing complications
- A clinical study which relates to a theoretical simulation of the glucose transport in the human placenta under various diabetic conditions
- Academy’s Corner
- American medical education: the evolution of excellence
- Original articles - Obstetrics
- Is epidural analgesia during labor related to retained placenta?
- Preventing intellectual disability during pregnancy: what are the potentially high yield targets?
- Evaluation of measured postpartum blood loss after vaginal delivery using a collector bag in relation to postpartum hemorrhage management strategies: a prospective observational study
- Original articles - Fetus
- Mutation analysis and prenatal diagnosis in a Chinese family with succinic semialdehyde dehydrogenase and a systematic review of the literature of reported ALDH5A1 mutations
- Original articles - Newborn
- Neurological disease or intellectual disability among sons of female Swedish dental personnel
- Seeking the best training model for difficult conversations in neonatology
- Meconium aspiration syndrome in infants of HIV-positive women: a case-control study
- Dopamine treatment does not need speed recovery of newborns from transient tachypnea
- Congress Calendar
- Congress Calendar
Articles in the same Issue
- Frontmatter
- Editorial
- Obesity and gestational diabetes in pregnancy: an evolving epidemic
- Original articles - Diabetes
- Is omitting the 3rd hour measurement in the 100 g oral glucose tolerance test feasible?
- Maternal hypoglycemia on 50 g glucose challenge test: outcomes are influenced by fetal gender
- Biological and biochemical characteristics of a Mediterranean population with Gestational Diabetes Mellitus
- Maternal and perinatal outcomes after bariatric surgery: a case control study
- A population-based comparison between actual maternal weight gain and the Institute of Medicine weight gain recommendations in singleton pregnancies
- The relationship between cesarean section rate in term singleton pregnancies, maternal weight, and weight gain during pregnancy
- Antenatal body mass index (BMI) and weight gain in pregnancy – its association with pregnancy and birthing complications
- A clinical study which relates to a theoretical simulation of the glucose transport in the human placenta under various diabetic conditions
- Academy’s Corner
- American medical education: the evolution of excellence
- Original articles - Obstetrics
- Is epidural analgesia during labor related to retained placenta?
- Preventing intellectual disability during pregnancy: what are the potentially high yield targets?
- Evaluation of measured postpartum blood loss after vaginal delivery using a collector bag in relation to postpartum hemorrhage management strategies: a prospective observational study
- Original articles - Fetus
- Mutation analysis and prenatal diagnosis in a Chinese family with succinic semialdehyde dehydrogenase and a systematic review of the literature of reported ALDH5A1 mutations
- Original articles - Newborn
- Neurological disease or intellectual disability among sons of female Swedish dental personnel
- Seeking the best training model for difficult conversations in neonatology
- Meconium aspiration syndrome in infants of HIV-positive women: a case-control study
- Dopamine treatment does not need speed recovery of newborns from transient tachypnea
- Congress Calendar
- Congress Calendar