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All That Wheezes Is Not Asthma

  • Christopher Gilbert
Published/Copyright: July 1, 2013

A 37-year old man was evaluated for severe asthma. Computed tomography of the chest revealed diffuse, end-expiratory tracheal narrowing (images A and B), suggesting severe tracheobronchomalacia. End-inspiration (image A) showed a slightly crescent-shaped yet widely patent trachea (red arrow). At end-expiration (image B), the trachea (red arrow) demonstrated severe dynamic collapse. In images A and B, the esophagus is identified (blue arrow). Tracheobronchomalacia was confirmed bronchoscopically (images C and D). During inspiration, a relatively normal tracheal diameter and distally visible main carina were seen (image C). During forced expiration (image D), flattening of the cartilaginous tracheal rings anteriorly and anterior bowing of the posterior tracheal wall occurred, producing airway collapse. The main carina was no longer visible secondary to near complete closure of the airway. Silicone Y stent placement improved symptoms and spirometric values, prompting tracheobronchoplasty evaluation.

Tracheobronchomalacia is characterized by excessive dynamic airway collapse due to weakening of tracheal or bronchial cartilaginous support. The true incidence of tracheobronchomalacia remains undefined; however, patients' symptoms are commonly misclassified as asthma or chronic bronchitis.1 Diagnosis is confirmed with radiographic imaging and bronchoscopy. Suspected tracheobronchomalacia requires referral and evaluation by trained interventional pulmonologists, thoracic surgeons, or both.


From Penn State Milton S. Hershey Medical Center in Pennsylvania. Dr Gilbert holds a master's degree in pharmacolgy
Address correspondence to Christopher Gilbert, DO, MS, Department of Pulmonary, Allergy, and Critical Care Medicine, Bronchoscopy and Interventional Pulmonology, Mail Code H0141, 500 University Dr, Hershey, PA 17033-0850. E-mail:

  1. Financial Disclosures: None reported.

Reference

1 Carden KA Boiselle PM Waltz DA Ernst A . Tracheomalacia and tracheobronchomalacia in children and adults: an in-depth review. Chest. 2005;127(3):984-1005.10.1378/chest.127.3.984Search in Google Scholar PubMed

Received: 2012-11-17
Revised: 2012-12-16
Accepted: 2013-01-02
Published Online: 2013-07-01
Published in Print: 2013-07-01

© 2013 The American Osteopathic Association

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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