A Curious Case of Recurrent Pneumonia
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Emily R. Thomas
A 52-year-old woman presented to the emergency department in February 2012 with a productive cough of 2 months duration and recurrent pneumonia. The patient had a history of recurrent bacterial pneumonias and stage IIIC squamous cell esophageal cancer that was managed with chemotherapy and radiotherapy. Chest imaging (panel A) revealed a right lower lobe infiltrate consistent with a possible early pneumonia. Because of the large amount of expectoration, computed tomography was performed, results of which revealed a large tracheoesophageal fistula approximately 1 cm proximal to the carina (panel B). The patient was sent to a tertiary care facility for treatment and was lost to follow-up.
In adults, 50% of acquired tracheoesophageal fistulas manifest in the context of a mediastinal malignancy.1 Mediastinal malignancies, which have an incidence of 4.5% in US adults, are caused by esophageal cancer in 77% of cases.2 Tracheoesophageal fistula is considered an urgent oncologic complication.3 Physicians should therefore consider tracheoesophageal fistula in the differential diagnosis for pneumonia in patients with a history of mediastinal cancer, particularly esophageal cancer.

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Financial Disclosures: None reported.
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Authors interested in contributing to “Clinical Images” should refer to the JAOA's “Information for Authors” at http://www.jaoa.org/misc/ifora.xhtml. Manuscripts should be submitted at http://mc04.manuscriptcentral.com/jaoa.
References
1 Diddee R Shaw IH . Acquired tracheo-oesophageal fistula in adults. Contin Educ Anaesth Crit Care Pain. 2006;6(3):105-108.10.1093/bjaceaccp/mkl019Search in Google Scholar
2 Burt M Diehl W Martini N et al. . Malignant esophagorespiratory fistula: management options and survival. Ann Thorac Surg.1991;52(6):1222-1228.10.1016/0003-4975(91)90005-BSearch in Google Scholar
3 Quint LF . Thoracic complications and emergencies in oncologic patients. Cancer Imaging. 2009;9(A):S75-S82.10.1102/1470-7330.2009.9031Search in Google Scholar PubMed PubMed Central
© 2012 The American Osteopathic Association
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
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- Letters
- Holding Rhetoric to a New Standard: What's the P Value of That Statement, Senator?
- Joining Forces: Military Perspectives for Osteopathic Medical Education
- Editorial
- Introducing the JAOA's New Online Manuscript Tracking System
- The Somatic Connection
- Self-Treatment of Myofascial Trigger Points Relieves Chronic Pelvic Pain
- Empirical Measurement of the Effects of Myofascial Release in Cervical and Lumbar Regions
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