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A Curious Case of Recurrent Pneumonia

  • Emily R. Thomas
Published/Copyright: October 1, 2012

A 52-year-old woman presented to the emergency department in February 2012 with a productive cough of 2 months duration and recurrent pneumonia. The patient had a history of recurrent bacterial pneumonias and stage IIIC squamous cell esophageal cancer that was managed with chemotherapy and radiotherapy. Chest imaging (panel A) revealed a right lower lobe infiltrate consistent with a possible early pneumonia. Because of the large amount of expectoration, computed tomography was performed, results of which revealed a large tracheoesophageal fistula approximately 1 cm proximal to the carina (panel B). The patient was sent to a tertiary care facility for treatment and was lost to follow-up.

In adults, 50% of acquired tracheoesophageal fistulas manifest in the context of a mediastinal malignancy.1 Mediastinal malignancies, which have an incidence of 4.5% in US adults, are caused by esophageal cancer in 77% of cases.2 Tracheoesophageal fistula is considered an urgent oncologic complication.3 Physicians should therefore consider tracheoesophageal fistula in the differential diagnosis for pneumonia in patients with a history of mediastinal cancer, particularly esophageal cancer.


Address correspondence to Emily R. Thomas, DO, Assistant Professor, West Virginia School of Osteopathic Medicine, 400 N Lee St, Lewisburg, WV 24901-1128. E-mail:

  1. Financial Disclosures: None reported.

  2. Authors interested in contributing to “Clinical Images” should refer to the JAOA's “Information for Authors” at http://www.jaoa.org/misc/ifora.xhtml. Manuscripts should be submitted at http://mc04.manuscriptcentral.com/jaoa.

References

1 Diddee R Shaw IH . Acquired tracheo-oesophageal fistula in adults. Contin Educ Anaesth Crit Care Pain. 2006;6(3):105-108.10.1093/bjaceaccp/mkl019Search in Google Scholar

2 Burt M Diehl W Martini N et al. . Malignant esophagorespiratory fistula: management options and survival. Ann Thorac Surg.1991;52(6):1222-1228.10.1016/0003-4975(91)90005-BSearch in Google Scholar

3 Quint LF . Thoracic complications and emergencies in oncologic patients. Cancer Imaging. 2009;9(A):S75-S82.10.1102/1470-7330.2009.9031Search in Google Scholar PubMed PubMed Central

Received: 2012-03-23
Revised: 2012-05-29
Accepted: 2012-06-05
Published Online: 2012-10-01
Published in Print: 2012-10-01

© 2012 The American Osteopathic Association

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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